Protein Alignment DNApol-iota and polh-1

DIOPT Version :9

• Sequence 1: NP_001287227.1
• Gene: DNApol-iota / 40965
• FlyBaseID: FBgn0037554
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: NP_497480.2
• Gene: polh-1 / 175337
• WormBaseID: WBGene00018721
• Length: 584
• Species: Caenorhabditis elegans
• Alignment Length: 624
• Identity: 143/624 - (22%)
• Similarity: 255/624 - (40%)
• Gaps: 141/624 - (22%)

  Fly    14 QRTIIHLDMDYFYAQVEEIRDPTLRSKALGIQQ------KNIVVTCNYVARAKGVTKLMLIAEAQ 72
            :|.|..:|||.||||||:..:|:|..:.:.:.|      :..::..:|.||..||.:.|.:|||:
 Worm     2 KRVISLIDMDCFYAQVEQRDNPSLWGQPVIVVQHSRQGIEGGILAVSYEARPFGVKRGMTVAEAK 66

  Fly    73 RICPDLVL--------VNGEDLAPYRQMSQRIFDLLLNYTP--LVEKLGFDENFMDVTA-----L 122
            ..||.:.:        |:..|:..||..|..:|.:|.||..  ::||...||.|:|::|     |
 Worm    67 LKCPQISICHVPIGEYVDKADIQKYRDASAEVFRVLNNYDSQIIIEKASVDEAFLDLSAYTNQKL 131

  Fly   123 VELRQAHVAEALLRPPVGH---TYPADGTPLS------------------NCDCGCAQRLAIGT- 165
            .|||:....|..|:..:.:   |:.|.|..:.                  ||.......:|..|
 Worm   132 QELRENEGLEEFLQAAITYLPTTHLATGEDVKENEHLREDVLLEYIENARNCTENLLLLIAAVTV 196

  Fly   166 -RIAQEIREELKLRLGITCCAGIAYNKLLAKLVGSSHEPNQQTVLVSTYAEQFMR--ELGDLKRV 227
             :|.|:|.||.:    ..|.||:..||::||||.:.|:|.|||::...|..:.:|  .:||::..
 Worm   197 EQIRQQIHEETQ----FFCSAGVGNNKMMAKLVCARHKPRQQTLIPWFYVREILRLTPIGDVRGF 257

  Fly   228 TG-IGQKTQCLLLEAGMSSVEQLQQCDMDVMRKKFGFETATRLRDLAFGRDTSLVRPSGKPKTIG 291
            .| :|.:.|.:|   .::.:.:|.:.|:..:.:.|. .....||.:|.|.....|||..:..:|.
 Worm   258 GGKMGNRIQEML---NITLMGELLEVDISQLIETFP-NQHEYLRSVAEGHCDEPVRPRKESSSIA 318

  Fly   292 M-EDACKPISVRTDVEERFRM--LLKRLVEQVAEDGRVPIAIKVVLRKFDSQKKSSHRETKQANI 353
            : ::....:|:|:.:|.:..:  |.|.|.:::|.|                  ::.::.|.: |:
 Worm   319 VSKNFPGKLSIRSVLELKKWLDGLTKELAKRLATD------------------QAENKRTAE-NL 364

  Fly   354 LPSLFKTSMCPGETGVSKVQLADGAQDKLLKIVM----RLFERIVDMSKPFN------------- 401
            :.||.               ..||...|.|||..    .|||:|....|..|
 Worm   365 VYSLL---------------TEDGKPQKTLKITSYHPDTLFEQIWAAMKGLNKTNATKNEDSGPW 414

  Fly   402 ---ITLLGLAFSKFQER-KVGSSSIANFLIKKADLEVQSITSLTNTSLTSPTAESPTSDECAFRS 462
               |..:.|:.::||.. ...:.||..:|.:|...:.:...::.:        |:...::..|..
 Worm   415 TPPILNISLSATRFQPGIPAQNRSIHEWLYEKKTRKSRRKAAIYD--------ENDGREDVIFVE 471

  Fly   463 SPTTFKPSDQFYRRRATTASPVPMLLDNGSESAATNSD----------FSDFSETEVEPSPKKSR 517
            .|...|..:...:...|....:.:..|:..:.....:|          ||..:...:.|..||..
 Worm   472 PPEKLKKPNPTPKSTGTDGDFIVLGSDSDDDVVQPKTDDNWIFVDGKKFSKMAWRHLPPDIKKHY 536

  Fly   518 IGRLLVSKRSRLAADVG----------DSAAEVASPSKL 546
            ..|:.:.:...|.:..|          |:|.:...|..|
 Worm   537 QHRIALEEARALKSKTGGSRKRAGAHTDNAQKPKKPKSL 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-iota	NP_001287227.1	PolY_Pol_iota	18..411	CDD:176457	116/462 (25%)
polh-1	NP_497480.2	PolY	7..426	CDD:391962	116/460 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0389
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593931at2759
OrthoFinder	1	1.000	-	-		FOG0001835
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4551
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850