DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DNApol-iota and esco1

DIOPT Version :9

Sequence 1:	NP_001287227.1	Gene:	DNApol-iota / 40965	FlyBaseID:	FBgn0037554	Length:	737	Species:	Drosophila melanogaster
Sequence 2:	XP_005174247.1	Gene:	esco1 / 100333282	ZFINID:	ZDB-GENE-130530-818	Length:	933	Species:	Danio rerio

Alignment Length:	487	Identity:	97/487 - (19%)
Similarity:	158/487 - (32%)	Gaps:	151/487 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   281 VRPSGKPKTIGMEDACKPI---SVRT-------DVEERFRMLLKRLVEQVA--EDGRVPIAIKVV 333
            |...|..|.:......|||   :::|       .:|..:..|.....|::.  :..::.:|.|..
Zfish   103 VLKKGNKKYVSRVKREKPIISETIKTVAAMFPVQIEHNYGRLFDMQAEEITLPKPDKIHVANKSE 167

  Fly   334 LRKFDSQKKSSHRETKQANILPSLFKTSMCPGETGVSKVQLA-DGAQDKLLKI---VMRLFERIV 394
            ::.....:.|...|.|:.:..|             |.|:.:: |...|.:.|.   :..|| :::
Zfish   168 MQALHETQASKAEEQKELHAEP-------------VEKITVSVDAKVDVMSKSPPPLEALF-KVI 218

  Fly   395 DMSKPFNITLLGLAFSKFQERK----------VGSSSIANFLIKKADLEVQSITSLTNTSLTSPT 449
            ..|.....:..|...|...|.:          |.|:.:|...::.:|..:.....:.|..:...|
Zfish   219 QESSLTKHSFSGKDISDMDELEVVNTCSLQDSVQSTDVAKVFLQDSDAFLDDDVEIENCVVEIET 283

  Fly   450 AESPTSD----------ECA----FRSSPTTFK----------PSDQFYRRRATTASPVPMLLDN 490
            .|....|          ||.    ..|||:..:          |..|....:|.|.:.:..|.:.
Zfish   284 YEDLDGDQGEVSKKQTSECVTCKEVNSSPSLPQESATDSSQELPKKQAMNPQARTKARLAALAEE 348

  Fly   491 -------------------------------GSESAATNS------DFSDFSE-TEVEPSPKKSR 517
                                           |:....||.      :..|.|| |||..|...|.
Zfish   349 RAAAAKKPPPRHFNLLALCEEIADDIASDAPGASDKTTNEQQQEDHESEDVSECTEVSESKDASE 413

  Fly   518 IGRLLVSKRSRLAADVGDSAAEVASPSKLRVCDLRLNSRDSEKDF--PMST---------TPSTS 571
                  ||....:.|:.:|  :.||.||    |:..|...||.:.  |...         ||:..
Zfish   414 ------SKEVNESKDLSES--KDASESK----DVSENKEVSETETCEPEEVVSENTAPPGTPNEE 466

  Fly   572 TSAPAP-------RFRTVQ---PPNT----------LLQRIDGSLRFVTTRTASRLSSNASSTAS 616
            |:.|.|       ||...|   |..|          .|::::.....:|.....:|.|:..:.|.
Zfish   467 TADPRPEDGTPKKRFFLSQMSVPLKTQEKKKLSRFQRLRQVELQRDKLTWTRVKKLKSDQVNQAG 531

  Fly   617 SPLPSPMDDSIAMS-APSTTTLPFPSPTTTAV 647
            |     ..||.|.| :||..|.|...|||.:|
Zfish   532 S-----QKDSEASSVSPSPATTPAQVPTTESV 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-iota	NP_001287227.1	PolY_Pol_iota	18..411	CDD:176457	25/145 (17%)
esco1	XP_005174247.1	zf-C2H2_3	703..737	CDD:290589
esco1	XP_005174247.1	Acetyltransf_13	856..918	CDD:290591
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4551
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030