Protein Alignment CG18249 and lrrc15

DIOPT Version :10

• Sequence 1: NP_001163549.1
• Gene: CG18249 / 40964
• FlyBaseID: FBgn0037553
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001074151.1
• Gene: lrrc15 / 791200
• ZFINID: ZDB-GENE-031113-8
• Length: 564
• Species: Danio rerio
• Alignment Length: 522
• Identity: 116/522 - (22%)
• Similarity: 184/522 - (35%)
• Gaps: 206/522 - (39%)

  Fly     6 YILLGICGLTVSDALAVYDASGRFNLSASCPDSFCSLSDRPVAYSATPALQLRELHLRNCSRQSI 70
            ::::|:|.:..              :::|||:| |......:.                |...|:
Zfish     6 FVIIGMCAMKA--------------VASSCPES-CQCQVTKIV----------------CQGFSV 39

  Fly    71 TWLVLQLTPGLRTLVIRNCA----------------TYHISKES--------------------- 98
            ..:.|.:.|.:..|||.|.:                |..::|.|
Zfish    40 KEIPLPMPPTINALVISNTSIQSLKPSDFQTFAETLTLFVAKNSNITEVEPHTFDQAFNLNALGF 104

  Fly    99 ------------------------------------LRPVENLTSLQMQGTSLGVLRDQIFNAVP 127
                                                |.|:.|:..|.:....|..|.:..|..:.
Zfish   105 SGTMLTSLPDNLFQNLTALTTLTLSGNKLEVLPSSLLTPLANVNKLDLSKNLLSSLSEDAFRGLD 169

  Fly   128 RLEILQLSQNFIHTVHVAAFQGLSKLRLLGLQGNAIAEILSSTLDPLMELVHLDLSRNELTTLPQ 192
            :||:|.|.:|.|..:|.:.|||||.||.|.||.|.:.:|.:...|.|:.|..|.|..|::..||.
Zfish   170 QLEMLMLQRNSIKQLHSSTFQGLSHLRSLFLQQNQLTDIPAGLFDDLVNLEVLHLQDNKIEQLPA 234

  Fly   193 NIFAKNKKLQTLLLNGNPLRILMPDVLGSLPNLRLLDL-------------GHAA--EL------ 236
            |:|||.:.|:.|.|:.|.|.:|...:..|||||..:.|             |..|  ||
Zfish   235 NLFAKVQNLKKLYLSSNRLSLLPSGIFLSLPNLTHISLYDNRLSRLMPETFGTMALQELWLYDNL 299

  Fly   237 -----EVMTLNLTNVQNLVLEGSSLSSLVINGGFIKLQAGNNELNHLQVGNKSSVIEMDLHGNLL 296
                 |.:..||||::.||:..:.: ..:..|.|       |.|..|:        |:.||.|.|
Zfish   300 LTHLEENVFSNLTNIRLLVISRNRI-QYISPGAF-------NGLKELK--------EVSLHTNRL 348

  Fly   297 NGNDTAALLRGMWNLQRLDLSKNRIEALPQHGSGLDASGTQELLILPSLKFLNLANNQLVRLPPE 361
            . |....:.||                                  ||:|..:::.|||:.::|.:
Zfish   349 T-NIEPGIFRG----------------------------------LPNLANISIENNQIKQIPIQ 378

  Fly   362 SPILSSRLSYLDLSHNLMLTLDVAILRSLSVLKGLYVEGNRLNTINYQKLHEEHPDLSELGLHDN 426
            .....||||.|::.:|.:..|....|.:||:::         |.|                ||:|
Zfish   379 LLDGVSRLSLLEMQNNSLQNLPKDFLNTLSIVE---------NVI----------------LHEN 418

  Fly   427 PW 428
            ||
Zfish   419 PW 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18249	NP_001163549.1	leucine-rich repeat	57..80	CDD:275380	3/22 (14%)
		LRR	105..433	CDD:443914	95/350 (27%)
		leucine-rich repeat	105..128	CDD:275380	4/22 (18%)
		leucine-rich repeat	129..152	CDD:275380	11/22 (50%)
		leucine-rich repeat	153..176	CDD:275380	9/22 (41%)
		leucine-rich repeat	177..200	CDD:275380	10/22 (45%)
		leucine-rich repeat	201..224	CDD:275380	8/22 (36%)
		leucine-rich repeat	225..258	CDD:275380	13/58 (22%)
		leucine-rich repeat	259..310	CDD:275380	13/50 (26%)
		leucine-rich repeat	311..344	CDD:275380	1/32 (3%)
		leucine-rich repeat	345..368	CDD:275380	5/22 (23%)
		leucine-rich repeat	369..390	CDD:275380	6/20 (30%)
		leucine-rich repeat	393..417	CDD:275380	2/23 (9%)
lrrc15	NP_001074151.1	LRRNT	21..48	CDD:214470	7/43 (16%)
		leucine-rich repeat	53..73	CDD:275380	4/19 (21%)
		LRR	74..418	CDD:443914	98/419 (23%)
		leucine-rich repeat	171..194	CDD:275380	11/22 (50%)
		leucine-rich repeat	195..218	CDD:275380	9/22 (41%)
		leucine-rich repeat	219..242	CDD:275380	10/22 (45%)
		leucine-rich repeat	243..266	CDD:275380	8/22 (36%)
		leucine-rich repeat	267..289	CDD:275380	3/21 (14%)
		leucine-rich repeat	290..313	CDD:275380	5/22 (23%)
		leucine-rich repeat	314..337	CDD:275380	6/30 (20%)
		leucine-rich repeat	338..361	CDD:275380	10/65 (15%)
		leucine-rich repeat	362..385	CDD:275380	5/22 (23%)
		LRRCT	418..467	CDD:214507	3/3 (100%)