DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18249 and CG7896

DIOPT Version :9

Sequence 1:NP_001163549.1 Gene:CG18249 / 40964 FlyBaseID:FBgn0037553 Length:559 Species:Drosophila melanogaster
Sequence 2:NP_651754.1 Gene:CG7896 / 43552 FlyBaseID:FBgn0039728 Length:1392 Species:Drosophila melanogaster


Alignment Length:627 Identity:149/627 - (23%)
Similarity:234/627 - (37%) Gaps:192/627 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    47 VAYSATPALQ-------------------LRELHLRNCSRQSITWLVLQLTPG------------ 80
            ||.:|.|.|:                   :|.|...:.||.:||    .:|||            
  Fly   298 VALAAVPGLKHLNLSSNMLQQLDYTHMQVVRSLESLDISRNTIT----TITPGTFREMGALKYLD 358

  Fly    81 -------------------LRTLVIRNCATYHISKESLRPVENLTSLQMQGTSLGVLRDQIFNAV 126
                               |:||:|::.....:...:|..:..|||||:....:..|..:|..::
  Fly   359 LSLNSLRTIEDDALEGLDSLQTLIIKDNNILLVPGSALGRLPQLTSLQLDYNRVAALSAEILGSL 423

  Fly   127 PRLEI--LQLSQNFIHTVHVAAFQGLSKLRLLGLQGNAIAEI-------LSSTLDPLM------- 175
            ...:|  |.||:|.|..:...:||..|.|..|.|.||::|.|       |.|||..|.       
  Fly   424 QAGDITTLSLSRNVIRELPPGSFQMFSSLHTLDLSGNSLAVINADTFAGLESTLMALKLSQNRLT 488

  Fly   176 ----------ELVHLDLSRNELTTLPQNIFAKNKKLQTLLLNGNPLRILMPDVLGSLPNLRLLDL 230
                      ||..||||.|.||.||..||.:.:.:|:|.|:||.|..|...:...|..|:::||
  Fly   489 GLGGAPWVLPELRSLDLSGNTLTELPSTIFEELENVQSLNLSGNHLTPLTGALFKPLDRLQVIDL 553

  Fly   231 GHAAELEVMTLNLTNVQNLVLEG-SSLSSLVINGGFIKLQAGNNELNHLQVG---NKSSVIEMDL 291
            ...        |:..:...:|.| ..|..:.:|         :|:|..||.|   |..::..:||
  Fly   554 SGC--------NIRQISGDLLAGLQDLKHIYLN---------DNQLQELQDGSFVNLWNISSIDL 601

  Fly   292 HGNLLNGNDTAALLRGMWNLQRLDLSKNRIEALP----QHGSG---LDASGTQELLILPS----- 344
            ..|.:....:.|.:..| .||:|||..|::.|..    ..|:|   ||.|..|...:.||     
  Fly   602 SNNRIGSIRSGAFVNVM-KLQKLDLHGNQLSAFKGEYFNTGTGIEELDISDNQLSYLFPSSFRIH 665

  Fly   345 --LKFLNLANNQLVRLPPESPILSSRLSYL---DLSHNLMLTLDVAILRSLSVLKGLYVEGNRLN 404
              |:.:..|||:....|.|   |.|.|.||   |||||.:.|::......|..|:.|.|..|:|:
  Fly   666 PRLREIRAANNKFSFFPAE---LISTLQYLEHIDLSHNQLKTIEELDFARLPRLRVLLVANNQLD 727

  Fly   405 TINYQKLHEE---------HPDLSELG--------------LHDN---PWSSGLYRKMFL----- 438
            .::....|..         |.:|..:|              |..|   ..|.|::.:..|     
  Fly   728 MVSEMAFHNSTQLQILDLAHNNLDRIGERTFEGLVRLEQLNLEGNRLSELSDGVFERTKLQMLEN 792

  Fly   439 -------------------YFTDRGVHL------QARPQNRVLNKSSRVDIDWPPNEGQAEAQKM 478
                               :|....|.|      :....:.::....|:|:.:.|...:|....:
  Fly   793 INLAHNRFEYAPLNALQRQFFFVSSVDLSHNKIKELPGDDSIMVNIKRIDLSFNPLSSKAVHNVL 857

  Fly   479 DPPGVTGIHPYWTLRDI------LAFVTLLVVMIILLMNLYH 514
            :.|.        |:|::      :..:.||....:..:||.|
  Fly   858 NEPK--------TVRELSLAGTGIENLELLETPFLQFLNLSH 891

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18249NP_001163549.1 leucine-rich repeat 57..80 CDD:275380 7/22 (32%)
LRR_8 104..163 CDD:290566 21/60 (35%)
leucine-rich repeat 105..128 CDD:275380 7/22 (32%)
LRR_RI 107..438 CDD:238064 112/403 (28%)
leucine-rich repeat 129..152 CDD:275380 8/24 (33%)
leucine-rich repeat 153..176 CDD:275380 12/46 (26%)
LRR_8 176..232 CDD:290566 24/55 (44%)
leucine-rich repeat 177..200 CDD:275380 12/22 (55%)
leucine-rich repeat 201..224 CDD:275380 8/22 (36%)
leucine-rich repeat 225..258 CDD:275380 7/33 (21%)
leucine-rich repeat 259..310 CDD:275380 12/53 (23%)
leucine-rich repeat 311..344 CDD:275380 13/39 (33%)
LRR_8 343..403 CDD:290566 24/69 (35%)
leucine-rich repeat 345..368 CDD:275380 7/22 (32%)
leucine-rich repeat 369..390 CDD:275380 9/23 (39%)
leucine-rich repeat 393..417 CDD:275380 7/32 (22%)
CG7896NP_651754.1 LRR_8 109..172 CDD:290566
leucine-rich repeat 109..132 CDD:275380
LRR_RI <132..338 CDD:238064 8/39 (21%)
leucine-rich repeat 133..161 CDD:275380
LRR_8 160..220 CDD:290566
leucine-rich repeat 162..185 CDD:275380
leucine-rich repeat 186..209 CDD:275380
leucine-rich repeat 210..233 CDD:275380
LRR_8 232..290 CDD:290566
leucine-rich repeat 234..257 CDD:275380
leucine-rich repeat 258..281 CDD:275380
LRR_RI 273..535 CDD:238064 65/240 (27%)
LRR_8 281..338 CDD:290566 8/39 (21%)
leucine-rich repeat 282..329 CDD:275380 5/30 (17%)
LRR_8 328..388 CDD:290566 13/63 (21%)
leucine-rich repeat 330..353 CDD:275380 8/26 (31%)
leucine-rich repeat 354..377 CDD:275380 0/22 (0%)
leucine-rich repeat 378..401 CDD:275380 5/22 (23%)
leucine-rich repeat 402..425 CDD:275380 7/22 (32%)
leucine-rich repeat 428..451 CDD:275380 8/22 (36%)
LRR_8 429..487 CDD:290566 20/57 (35%)
leucine-rich repeat 452..473 CDD:275380 7/20 (35%)
leucine-rich repeat 477..497 CDD:275378 2/19 (11%)
LRR_8 498..558 CDD:290566 24/67 (36%)
leucine-rich repeat 500..523 CDD:275380 12/22 (55%)
LRR_RI 502..769 CDD:238064 80/287 (28%)
leucine-rich repeat 524..547 CDD:275380 8/22 (36%)
leucine-rich repeat 548..571 CDD:275380 6/30 (20%)
LRR_8 572..630 CDD:290566 19/67 (28%)
leucine-rich repeat 572..595 CDD:275380 8/31 (26%)
leucine-rich repeat 596..619 CDD:275380 5/23 (22%)
LRR_8 619..678 CDD:290566 19/58 (33%)
leucine-rich repeat 620..643 CDD:275380 8/22 (36%)
leucine-rich repeat 644..667 CDD:275380 6/22 (27%)
LRR_8 666..726 CDD:290566 22/62 (35%)
leucine-rich repeat 668..691 CDD:275380 9/25 (36%)
leucine-rich repeat 692..715 CDD:275380 8/22 (36%)
LRR_8 714..774 CDD:290566 11/59 (19%)
leucine-rich repeat 716..739 CDD:275380 6/22 (27%)
leucine-rich repeat 740..761 CDD:275380 3/20 (15%)
leucine-rich repeat 764..789 CDD:275380 5/24 (21%)
leucine-rich repeat 790..810 CDD:275380 0/19 (0%)
leucine-rich repeat 818..850 CDD:275380 5/31 (16%)
leucine-rich repeat 863..883 CDD:275378 3/19 (16%)
LRR_RI <878..1070 CDD:238064 5/14 (36%)
LRR_8 884..944 CDD:290566 3/8 (38%)
LRR_4 884..925 CDD:289563 3/8 (38%)
leucine-rich repeat 884..907 CDD:275380 3/8 (38%)
leucine-rich repeat 908..933 CDD:275380
leucine-rich repeat 934..955 CDD:275380
leucine-rich repeat 958..982 CDD:275380
leucine-rich repeat 983..1055 CDD:275380
leucine-rich repeat 1009..1033 CDD:275380
leucine-rich repeat 1058..1085 CDD:275380
TPKR_C2 1121..1168 CDD:301599
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453784
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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