Protein Alignment CG18249 and CG7896

DIOPT Version :10

• Sequence 1: NP_001163549.1
• Gene: CG18249 / 40964
• FlyBaseID: FBgn0037553
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_651754.1
• Gene: CG7896 / 43552
• FlyBaseID: FBgn0039728
• Length: 1392
• Species: Drosophila melanogaster
• Alignment Length: 627
• Identity: 149/627 - (23%)
• Similarity: 234/627 - (37%)
• Gaps: 192/627 - (30%)

  Fly    47 VAYSATPALQ-------------------LRELHLRNCSRQSITWLVLQLTPG------------ 80
            ||.:|.|.|:                   :|.|...:.||.:||    .:|||
  Fly   298 VALAAVPGLKHLNLSSNMLQQLDYTHMQVVRSLESLDISRNTIT----TITPGTFREMGALKYLD 358

  Fly    81 -------------------LRTLVIRNCATYHISKESLRPVENLTSLQMQGTSLGVLRDQIFNAV 126
                               |:||:|::.....:...:|..:..|||||:....:..|..:|..::
  Fly   359 LSLNSLRTIEDDALEGLDSLQTLIIKDNNILLVPGSALGRLPQLTSLQLDYNRVAALSAEILGSL 423

  Fly   127 PRLEI--LQLSQNFIHTVHVAAFQGLSKLRLLGLQGNAIAEI-------LSSTLDPLM------- 175
            ...:|  |.||:|.|..:...:||..|.|..|.|.||::|.|       |.|||..|.
  Fly   424 QAGDITTLSLSRNVIRELPPGSFQMFSSLHTLDLSGNSLAVINADTFAGLESTLMALKLSQNRLT 488

  Fly   176 ----------ELVHLDLSRNELTTLPQNIFAKNKKLQTLLLNGNPLRILMPDVLGSLPNLRLLDL 230
                      ||..||||.|.||.||..||.:.:.:|:|.|:||.|..|...:...|..|:::||
  Fly   489 GLGGAPWVLPELRSLDLSGNTLTELPSTIFEELENVQSLNLSGNHLTPLTGALFKPLDRLQVIDL 553

  Fly   231 GHAAELEVMTLNLTNVQNLVLEG-SSLSSLVINGGFIKLQAGNNELNHLQVG---NKSSVIEMDL 291
            ...        |:..:...:|.| ..|..:.:|         :|:|..||.|   |..::..:||
  Fly   554 SGC--------NIRQISGDLLAGLQDLKHIYLN---------DNQLQELQDGSFVNLWNISSIDL 601

  Fly   292 HGNLLNGNDTAALLRGMWNLQRLDLSKNRIEALP----QHGSG---LDASGTQELLILPS----- 344
            ..|.:....:.|.:..| .||:|||..|::.|..    ..|:|   ||.|..|...:.||
  Fly   602 SNNRIGSIRSGAFVNVM-KLQKLDLHGNQLSAFKGEYFNTGTGIEELDISDNQLSYLFPSSFRIH 665

  Fly   345 --LKFLNLANNQLVRLPPESPILSSRLSYL---DLSHNLMLTLDVAILRSLSVLKGLYVEGNRLN 404
              |:.:..|||:....|.|   |.|.|.||   |||||.:.|::......|..|:.|.|..|:|:
  Fly   666 PRLREIRAANNKFSFFPAE---LISTLQYLEHIDLSHNQLKTIEELDFARLPRLRVLLVANNQLD 727

  Fly   405 TINYQKLHEE---------HPDLSELG--------------LHDN---PWSSGLYRKMFL----- 438
            .::....|..         |.:|..:|              |..|   ..|.|::.:..|
  Fly   728 MVSEMAFHNSTQLQILDLAHNNLDRIGERTFEGLVRLEQLNLEGNRLSELSDGVFERTKLQMLEN 792

  Fly   439 -------------------YFTDRGVHL------QARPQNRVLNKSSRVDIDWPPNEGQAEAQKM 478
                               :|....|.|      :....:.::....|:|:.:.|...:|....:
  Fly   793 INLAHNRFEYAPLNALQRQFFFVSSVDLSHNKIKELPGDDSIMVNIKRIDLSFNPLSSKAVHNVL 857

  Fly   479 DPPGVTGIHPYWTLRDI------LAFVTLLVVMIILLMNLYH 514
            :.|.        |:|::      :..:.||....:..:||.|
  Fly   858 NEPK--------TVRELSLAGTGIENLELLETPFLQFLNLSH 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18249	NP_001163549.1	leucine-rich repeat	57..80	CDD:275380	7/22 (32%)
		LRR	105..433	CDD:443914	114/400 (29%)
		leucine-rich repeat	105..128	CDD:275380	7/22 (32%)
		leucine-rich repeat	129..152	CDD:275380	8/24 (33%)
		leucine-rich repeat	153..176	CDD:275380	12/46 (26%)
		leucine-rich repeat	177..200	CDD:275380	12/22 (55%)
		leucine-rich repeat	201..224	CDD:275380	8/22 (36%)
		leucine-rich repeat	225..258	CDD:275380	7/33 (21%)
		leucine-rich repeat	259..310	CDD:275380	12/53 (23%)
		leucine-rich repeat	311..344	CDD:275380	13/39 (33%)
		leucine-rich repeat	345..368	CDD:275380	7/22 (32%)
		leucine-rich repeat	369..390	CDD:275380	9/23 (39%)
		leucine-rich repeat	393..417	CDD:275380	7/32 (22%)
CG7896	NP_651754.1	PRK15370	20..>410	CDD:185268	24/115 (21%)
		leucine-rich repeat	109..132	CDD:275380
		leucine-rich repeat	133..161	CDD:275380
		leucine-rich repeat	162..185	CDD:275380
		leucine-rich repeat	186..209	CDD:275380
		leucine-rich repeat	210..233	CDD:275380
		leucine-rich repeat	234..257	CDD:275380
		PLN00113	237..>750	CDD:215061	127/476 (27%)
		leucine-rich repeat	258..281	CDD:275380
		leucine-rich repeat	282..329	CDD:275380	5/30 (17%)
		leucine-rich repeat	330..353	CDD:275380	8/26 (31%)
		leucine-rich repeat	354..377	CDD:275380	0/22 (0%)
		leucine-rich repeat	378..401	CDD:275380	5/22 (23%)
		leucine-rich repeat	402..425	CDD:275380	7/22 (32%)
		leucine-rich repeat	428..451	CDD:275380	8/22 (36%)
		leucine-rich repeat	452..473	CDD:275380	7/20 (35%)
		leucine-rich repeat	477..497	CDD:275378	2/19 (11%)
		leucine-rich repeat	500..523	CDD:275380	12/22 (55%)
		leucine-rich repeat	524..547	CDD:275380	8/22 (36%)
		leucine-rich repeat	548..571	CDD:275380	6/30 (20%)
		leucine-rich repeat	572..595	CDD:275380	8/31 (26%)
		leucine-rich repeat	596..619	CDD:275380	5/23 (22%)
		leucine-rich repeat	620..643	CDD:275380	8/22 (36%)
		leucine-rich repeat	644..667	CDD:275380	6/22 (27%)
		leucine-rich repeat	668..691	CDD:275380	9/25 (36%)
		LRR	<684..1020	CDD:443914	42/219 (19%)
		leucine-rich repeat	692..715	CDD:275380	8/22 (36%)
		leucine-rich repeat	716..739	CDD:275380	6/22 (27%)
		leucine-rich repeat	740..761	CDD:275380	3/20 (15%)
		leucine-rich repeat	764..789	CDD:275380	5/24 (21%)
		leucine-rich repeat	790..810	CDD:275380	0/19 (0%)
		leucine-rich repeat	818..850	CDD:275380	5/31 (16%)
		leucine-rich repeat	863..883	CDD:275378	3/19 (16%)
		leucine-rich repeat	884..907	CDD:275380	3/8 (38%)
		leucine-rich repeat	908..933	CDD:275380
		leucine-rich repeat	934..955	CDD:275380
		leucine-rich repeat	958..982	CDD:275380
		leucine-rich repeat	983..1055	CDD:275380
		leucine-rich repeat	1009..1033	CDD:275380
		leucine-rich repeat	1058..1085	CDD:275380
		LRRCT	1121..1168	CDD:214507