Protein Alignment CG18249 and cDIP

DIOPT Version :10

• Sequence 1: NP_001163549.1
• Gene: CG18249 / 40964
• FlyBaseID: FBgn0037553
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_650951.1
• Gene: cDIP / 42512
• FlyBaseID: FBgn0038865
• Length: 554
• Species: Drosophila melanogaster
• Alignment Length: 375
• Identity: 96/375 - (25%)
• Similarity: 158/375 - (42%)
• Gaps: 43/375 - (11%)

  Fly    40 CSLSDRPVAYSATPALQLRELHLRNCSRQSITWLVLQLTPGLRTLVIRNCATYHISKESLRPVEN 104
            |:.::.|:....|  |::.||.:|.|..:.|.|....:  |...|||...:..||.
  Fly   103 CTFTNFPLRLFYT--LEVSELDMRGCGIRFIYWENFSI--GADKLVILLLSDNHIE--------- 154

  Fly   105 LTSLQMQGTSLGVLRDQIFNAVPRLEILQLSQNFIHTVHVAAFQGLSKLRLLGLQGNAIAEILSS 169
                        ||..:.|.....||.:.|::|.:..:...||..|.||:.|.|..|.:..:.:.
  Fly   155 ------------VLPTKTFRGAGNLEFIFLNRNKLGKLQAGAFDNLLKLQYLDLTENRLEALAAD 207

  Fly   170 TLDPLMELVHLDLSRNELTTLPQNIFAKNKKLQTLLLNGNPLRILMPDVL---GSLPNLRLLDLG 231
            ....|..|.|:.|:.|:|||:..::||.|..|.::.:..|.||.:.....   |....::.:||.
  Fly   208 VFAGLKSLRHVGLAGNQLTTIESDLFAHNPDLLSVAMQNNRLREVGEYAFRSRGRHHQMQYVDLS 272

  Fly   232 HAAELEVMTLNLTNVQNLVLEGSSLSSLVINGGFIKLQAGNNELNHLQVGNKSSVIEMDLHGNLL 296
            :..||.|:.||: |..||.....||..:.:.|....:...:|.:..|......::..:.|..|.|
  Fly   273 NNPELVVLLLNI-NATNLTARNCSLDRVNLYGSVTNVDLSDNRVRELYFPASEALEHLVLRNNSL 336

  Fly   297 NGNDTAALLRGMWNLQRLDLSKNRIEALPQHGSGLDASGTQELLILPSLKFLNLANNQLVRLPPE 361
              ...|:|.| :..|:.||::.|     |..|...|...|      |.|:.|.|.|...:.||.|
  Fly   337 --VQLASLSR-VPRLRHLDVADN-----PNLGQLPDGWRT------PHLEMLVLRNTGQMELPLE 387

  Fly   362 SPILSSRLSYLDLSHNLMLTLDVAILRSLSVLKGLYVEGNRLNTINYQKL 411
            :......|..||:|.|.:..:|.:...:|:.|...|:.||..|..:.:.:
  Fly   388 ALQGMQNLQKLDISGNNLTEIDPSAFPTLTQLTHFYIHGNNWNCFSLRNI 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18249	NP_001163549.1	leucine-rich repeat	57..80	CDD:275380	6/22 (27%)
		LRR	105..433	CDD:443914	80/310 (26%)
		leucine-rich repeat	105..128	CDD:275380	3/22 (14%)
		leucine-rich repeat	129..152	CDD:275380	7/22 (32%)
		leucine-rich repeat	153..176	CDD:275380	5/22 (23%)
		leucine-rich repeat	177..200	CDD:275380	10/22 (45%)
		leucine-rich repeat	201..224	CDD:275380	5/25 (20%)
		leucine-rich repeat	225..258	CDD:275380	12/32 (38%)
		leucine-rich repeat	259..310	CDD:275380	9/50 (18%)
		leucine-rich repeat	311..344	CDD:275380	8/32 (25%)
		leucine-rich repeat	345..368	CDD:275380	7/22 (32%)
		leucine-rich repeat	369..390	CDD:275380	6/20 (30%)
		leucine-rich repeat	393..417	CDD:275380	5/19 (26%)
cDIP	NP_650951.1	LRR	107..>410	CDD:443914	88/342 (26%)
		leucine-rich repeat	118..142	CDD:275380	7/25 (28%)
		leucine-rich repeat	143..166	CDD:275380	8/43 (19%)
		leucine-rich repeat	167..190	CDD:275380	7/22 (32%)
		leucine-rich repeat	191..214	CDD:275380	5/22 (23%)
		leucine-rich repeat	215..238	CDD:275380	10/22 (45%)
		leucine-rich repeat	239..265	CDD:275380	5/25 (20%)
		leucine-rich repeat	266..325	CDD:275380	15/59 (25%)
		leucine-rich repeat	326..347	CDD:275380	6/23 (26%)
		leucine-rich repeat	348..394	CDD:275380	16/56 (29%)
		leucine-rich repeat	395..418	CDD:275380	7/22 (32%)