Protein Alignment CG18249 and CG4950

DIOPT Version :10

• Sequence 1: NP_001163549.1
• Gene: CG18249 / 40964
• FlyBaseID: FBgn0037553
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_648855.2
• Gene: CG4950 / 39783
• FlyBaseID: FBgn0036587
• Length: 574
• Species: Drosophila melanogaster
• Alignment Length: 577
• Identity: 128/577 - (22%)
• Similarity: 241/577 - (41%)
• Gaps: 102/577 - (17%)

  Fly    23 YDASGRFNLSASCPDSFCSLSDRPVAYSAT-------PALQLRELHLRNCSRQSITWLVLQLTPG 80
            ||:.|..:::    ::||:::...|.:|..       |...::.:.....:...:.:.:.:..|.
  Fly    35 YDSMGYMDVN----EAFCTVTGFTVTHSQNVVIKNIPPGNMVKFMKFYESTLLYMPFHLFETFPY 95

  Fly    81 LRTLVIRNCATYHISKESLRPVENLTSLQMQGTSLGVLRDQIFNAVPRLEILQLSQNFIHTVHVA 145
            |:||.:.|.....:::.:.....|||.|.:...:|..::..:|.....|..|.||.|.|.::.|.
  Fly    96 LKTLDVSNTNILELTRNAFSAASNLTYLNLAYNNLTSIQTSVFIGANVLMRLDLSYNEISSLSVN 160

  Fly   146 AFQGLSKLRLLGLQGNAIAEILSSTLDPLMELVHLDLSRNELTTLPQNIFAKNKKLQTLLLNGNP 210
            ||.||..:..:.|.||.:.|:.:........|..:....|.||::...:|...::::.:.|:.|.
  Fly   161 AFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLTSIQPEVFRNMRRIKEVNLSNNR 225

  Fly   211 LRILMPDVLGSLPNLRLLDLGHAAELEVMTLNLTN-VQNLVLEGSSLSSLVING-GFIKLQAGNN 273
            |..:.||......:|..|.|.: .||:...|...| |..|.|:.:.|::|.||. .|::  |.:|
  Fly   226 LIFIHPDTFADAASLENLVLSY-NELKNFQLTEKNIVHQLHLDNNYLTNLTINATRFVR--ASHN 287

  Fly   274 ELNHLQVGNKSSVIEMDLHGNLLNGNDTAALLRGMWNLQRLDLSKNRIEALP-------QHGSGL 331
            :::.|.:.....:..:||..|.|:   :.:.:..:.::..||:|.|.|..|.       :...||
  Fly   288 QISELFLHQSLHIETLDLSANKLS---SISNITNITHMLYLDVSDNPIGPLNISTFSQLKRLRGL 349

  Fly   332 DASGTQELLILPSLKFLNLANNQLVRLPPESPILSSRLSYLDLSHN--LMLTLDVAILRSLSVLK 394
            :..||.    :..|||...:..:.             |..||||.|  .:|.||: .:..|:.||
  Fly   350 NLRGTG----IRELKFGMFSKQKY-------------LEELDLSFNNLTILNLDM-FVPYLTNLK 396

  Fly   395 GLYVEGNRLNTINYQK-LHEEHPDLSELGLHDNPWSSGLYRKMFLYFTDRGVHL---QARPQNRV 455
            ...::||.|..:...: ..|..|.|.:||:..|.::..     :|:      ||   .:.|::.|
  Fly   397 KFLIDGNGLTELQGNRTFSEAFPQLQKLGVSRNRFNCS-----YLH------HLLIPPSLPESVV 450

  Fly   456 LNKSSRVDIDWPPN---------------------EGQAEAQ------KMDPPGVTGIHP----- 488
            ||.....::|..|:                     |.:.|:|      ::|   :.|.|.
  Fly   451 LNIEPDTNLDETPHIRDVSCISQSQEVVNASFTAEESKLESQIQMLSKQLD---IVGSHSKNLEL 512

  Fly   489 YWTLRDILAFVT--LLVVMIILLMNLYHILEEEGCLRRFRHWRRSRTLGQNTSTTRN 543
            :.....|.|:|.  |::|.::.|:.|.::..:    |..|:.|.|.....|.:...|
  Fly   513 HLAFMQIFAYVMGGLVLVGVVSLITLRYLKNQ----RSGRYDRSSIVFRSNATMEAN 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18249	NP_001163549.1	leucine-rich repeat	57..80	CDD:275380	0/22 (0%)
		LRR	105..433	CDD:443914	86/339 (25%)
		leucine-rich repeat	105..128	CDD:275380	5/22 (23%)
		leucine-rich repeat	129..152	CDD:275380	11/22 (50%)
		leucine-rich repeat	153..176	CDD:275380	4/22 (18%)
		leucine-rich repeat	177..200	CDD:275380	5/22 (23%)
		leucine-rich repeat	201..224	CDD:275380	5/22 (23%)
		leucine-rich repeat	225..258	CDD:275380	11/33 (33%)
		leucine-rich repeat	259..310	CDD:275380	11/51 (22%)
		leucine-rich repeat	311..344	CDD:275380	10/39 (26%)
		leucine-rich repeat	345..368	CDD:275380	3/22 (14%)
		leucine-rich repeat	369..390	CDD:275380	9/22 (41%)
		leucine-rich repeat	393..417	CDD:275380	6/24 (25%)
CG4950	NP_648855.2	LRR	96..411	CDD:443914	85/338 (25%)
		leucine-rich repeat	96..119	CDD:275380	4/22 (18%)
		leucine-rich repeat	120..143	CDD:275380	5/22 (23%)
		leucine-rich repeat	144..167	CDD:275380	11/22 (50%)
		leucine-rich repeat	168..191	CDD:275380	4/22 (18%)
		leucine-rich repeat	192..215	CDD:275380	5/22 (23%)
		leucine-rich repeat	216..239	CDD:275380	5/22 (23%)
		leucine-rich repeat	240..299	CDD:275380	18/61 (30%)
		leucine-rich repeat	300..321	CDD:275380	4/23 (17%)
		leucine-rich repeat	322..345	CDD:275380	6/22 (27%)
		leucine-rich repeat	346..365	CDD:275380	7/22 (32%)
		leucine-rich repeat	370..394	CDD:275380	10/24 (42%)
		leucine-rich repeat	395..420	CDD:275380	6/24 (25%)