Protein Alignment CG18249 and CG4168

DIOPT Version :10

• Sequence 1: NP_001163549.1
• Gene: CG18249 / 40964
• FlyBaseID: FBgn0037553
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_609740.4
• Gene: CG4168 / 34889
• FlyBaseID: FBgn0028888
• Length: 1330
• Species: Drosophila melanogaster
• Alignment Length: 657
• Identity: 145/657 - (22%)
• Similarity: 246/657 - (37%)
• Gaps: 173/657 - (26%)

  Fly     1 MHFYKYILLGICGLTVSDALAVYDASGRFNLSASCPDSFCSLSDRPVAYSATPALQLR---ELHL 62
            :|..||:.|      .|:.::      :.|...|..::...||.....:|..|.|.|:   :|..
  Fly   434 LHHLKYLYL------TSNQIS------QLNNLPSFTENLRVLSLSGNNFSMIPVLGLKNYTQLSY 486

  Fly    63 RNCSRQSIT------WLVLQLTPGLRTLVIRNCATYHISKESLRPVENLTSLQMQGTSLGVLRDQ 121
            .|....|||      :.|......|:|:::||....|:...|...:|.:..:.:....:.:....
  Fly   487 LNMGYNSITDIPEGIFAVDSWGSNLQTILLRNNKITHLHLGSFAGLEQIQEISLSFNDITIHHPL 551

  Fly   122 IFNAVPR-LEILQLS------QNFIHTVHVAAFQGLSKLRLLGLQGNAIAEILSSTLDPLMELVH 179
            :|..|.| |:||:||      ::......:.|...||:|..|||..|.:.::.:.:...:.||.:
  Fly   552 VFENVSRTLKILELSFAVFPARSLESLDPLDALLPLSQLIWLGLDNNNLKQVSNESFAQMRELSY 616

  Fly   180 LDLSRNELTTLPQNIFAKNK--------------------------KLQTLLLNGNPLRILMPDV 218
            ::||.|:|.|||:.:|..:.                          .||||.|..|.||.:....
  Fly   617 INLSFNQLKTLPRGLFQSDAHSHLVEIDLSYNGLERLEAQTFHSLGDLQTLNLQSNRLRTIARHA 681

  Fly   219 LGSLPNLRLLDLGHAAELEV----MTLNLTNVQNLVLEGSSLSSLVINGGFIKLQAGNNEL---- 275
            ..:|..||.|||.:...:.:    .|: |.|:..|.|..:.|.||.:. .|:.:......|
  Fly   682 FHNLEFLRYLDLSYNRLVNISHGAFTV-LPNLAALDLMHNQLCSLSLK-SFLYVSNTTTPLRLNV 744

  Fly   276 --NHL-----QVGNKSSVIEMDLHGNLLNGNDTAALLRGMWNLQRLDLSKNRIEALPQHGSGLDA 333
              ||:     ::.:...:.::|:..|.:..:|:...|..  .|:.|:|:.|::.:|..|..|
  Fly   745 SHNHIASFYDELSSYMYIYQLDISHNHVTKSDSFTNLAN--TLRFLNLAHNQLGSLQSHAFG--- 804

  Fly   334 SGTQELLILPSLKFLNLANNQLVRLPPESPILSSRLSYLDLSHNLMLTLDVAILRSLSVLKGLYV 398
                   .|..|:.||:|:|.|..|...|....:.|..||||||.:..|.|....:|..|:.|.:
  Fly   805 -------DLEFLEILNVAHNNLTSLRRRSFQGLNSLQELDLSHNQLDQLQVEQFSNLRKLRILRI 862

  Fly   399 EGNRL---------NT-INYQKLHEEH------PDLSELGL--------HDNPWSSGLYRKMFLY 439
            ..|||         || :.:..:.|..      |..:::|.        |:|           |.
  Fly   863 NSNRLRALPREVFMNTRLEFLDIAENQLSVWPVPAFTDIGFTLRSIQMSHNN-----------LE 916

  Fly   440 FTDRGVHLQAR-------PQNRV----------LNKSSRVDIDWPPNEGQAEAQKMDPPGVTGIH 487
            :.|..:.:.::       .:||:          ||..:.:|:.             ..|.||
  Fly   917 YLDASMFINSQFLYDISLARNRITILPDNTFSFLNNLTNLDLS-------------QNPLVT--- 965

  Fly   488 PYWTLRDILAFVTLLVVMIILLMNLYHI--------------------LEEEGCLRRFRHWRRSR 532
              ..||::......|..:.:..|.||.:                    |...|.||..||...|.
  Fly   966 --TNLREVFVHTPRLRKLSLHHMGLYVLPPLKLPLLSYLDVSGNYLQELSPLGSLRHLRHVNVSH 1028

  Fly   533 TLGQNTS 539
            ....|.|
  Fly  1029 NKLTNAS 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18249	NP_001163549.1	leucine-rich repeat	57..80	CDD:275380	7/31 (23%)
		LRR	105..433	CDD:443914	94/399 (24%)
		leucine-rich repeat	105..128	CDD:275380	2/22 (9%)
		leucine-rich repeat	129..152	CDD:275380	7/28 (25%)
		leucine-rich repeat	153..176	CDD:275380	5/22 (23%)
		leucine-rich repeat	177..200	CDD:275380	9/48 (19%)
		leucine-rich repeat	201..224	CDD:275380	9/22 (41%)
		leucine-rich repeat	225..258	CDD:275380	11/36 (31%)
		leucine-rich repeat	259..310	CDD:275380	9/61 (15%)
		leucine-rich repeat	311..344	CDD:275380	8/32 (25%)
		leucine-rich repeat	345..368	CDD:275380	8/22 (36%)
		leucine-rich repeat	369..390	CDD:275380	9/20 (45%)
		leucine-rich repeat	393..417	CDD:275380	8/39 (21%)
CG4168	NP_609740.4	PRK15370	<69..>353	CDD:185268
		leucine-rich repeat	99..118	CDD:275380
		leucine-rich repeat	122..146	CDD:275380
		leucine-rich repeat	147..170	CDD:275380
		leucine-rich repeat	171..194	CDD:275380
		leucine-rich repeat	195..214	CDD:275380
		leucine-rich repeat	215..236	CDD:275380
		leucine-rich repeat	266..287	CDD:275380
		leucine-rich repeat	288..311	CDD:275380
		leucine-rich repeat	312..338	CDD:275380
		LRR	<338..651	CDD:443914	52/228 (23%)
		leucine-rich repeat	339..365	CDD:275380
		leucine-rich repeat	366..388	CDD:275380
		leucine-rich repeat	389..412	CDD:275380
		leucine-rich repeat	414..436	CDD:275380	0/1 (0%)
		leucine-rich repeat	437..459	CDD:275380	6/33 (18%)
		leucine-rich repeat	460..483	CDD:275380	6/22 (27%)
		leucine-rich repeat	484..510	CDD:275380	6/25 (24%)
		leucine-rich repeat	511..534	CDD:275380	6/22 (27%)
		leucine-rich repeat	535..589	CDD:275380	10/53 (19%)
		LRR	543..971	CDD:443914	106/470 (23%)
		leucine-rich repeat	590..613	CDD:275380	5/22 (23%)
		leucine-rich repeat	614..639	CDD:275380	9/24 (38%)
		leucine-rich repeat	640..663	CDD:275380	0/22 (0%)
		leucine-rich repeat	664..687	CDD:275380	9/22 (41%)
		leucine-rich repeat	688..711	CDD:275380	7/23 (30%)
		leucine-rich repeat	712..735	CDD:275380	6/23 (26%)
		leucine-rich repeat	740..783	CDD:275380	7/42 (17%)
		leucine-rich repeat	785..808	CDD:275380	8/32 (25%)
		leucine-rich repeat	809..832	CDD:275380	8/22 (36%)
		leucine-rich repeat	833..856	CDD:275380	10/22 (45%)
		leucine-rich repeat	857..879	CDD:275380	6/21 (29%)
		leucine-rich repeat	880..900	CDD:275380	2/19 (11%)
		leucine-rich repeat	905..928	CDD:275380	4/33 (12%)
		LRR	911..>1203	CDD:443914	27/154 (18%)
		leucine-rich repeat	929..952	CDD:275380	3/22 (14%)
		leucine-rich repeat	953..977	CDD:275380	6/41 (15%)
		leucine-rich repeat	978..1020	CDD:275380	7/41 (17%)
		leucine-rich repeat	1045..1068	CDD:275380
		leucine-rich repeat	1069..1090	CDD:275380
		leucine-rich repeat	1091..1114	CDD:275380
		leucine-rich repeat	1115..1161	CDD:275380
		leucine-rich repeat	1162..1190	CDD:275380
		PCC	1230..>1298	CDD:188093