Protein Alignment CG18249 and CG42346

DIOPT Version :10

• Sequence 1: NP_001163549.1
• Gene: CG18249 / 40964
• FlyBaseID: FBgn0037553
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001036303.2
• Gene: CG42346 / 3355160
• FlyBaseID: FBgn0259677
• Length: 1817
• Species: Drosophila melanogaster
• Alignment Length: 502
• Identity: 119/502 - (23%)
• Similarity: 188/502 - (37%)
• Gaps: 149/502 - (29%)

  Fly    57 LRELHLRNCSRQSITWLVLQLTPGLRTLVIRNCATYHISKESLRPVENLTSLQMQGTSLGVLRDQ 121
            |||:.|.|...:.:...|.:..|.|:.|.|:..:...|..::...:||:..:.:|...|.||.|.
  Fly   653 LREVRLHNNRIRRVRRGVFEPLPSLQELHIQKNSIEDIEPQAFHTLENMQHINLQDNQLTVLEDI 717

  Fly   122 IFNAVPRLEILQLSQNFIHTVHVAAFQGLSK---------------------------------- 152
            ..:....|..:||..|::|.||...|....|
  Fly   718 FPDENSSLLSVQLEANYLHKVHPRTFSRQQKVQIMWLKDNQLTRVERSFFADTPQLGRLYLSDNK 782

  Fly   153 --------------LRLLGLQGNAIAEILSSTLDPLMELVHLDLSRNELTTLPQNIFAKNKKLQT 203
                          |:.|.|.||.:.::......||.:|..|.|:||.:..:....|||.|.|::
  Fly   783 IRDIEKDTFVNLLLLQFLDLSGNQLRQLRRDYFAPLQDLEELSLARNHIEAIEGYAFAKLKNLKS 847

  Fly   204 LLLNGNPLRILMPDVLGSLPNLRLLDLGHAA----------------EL----------EVMTLN 242
            |.|:.|||..|..|:..:...|..|:||:.:                ||          ::.||:
  Fly   848 LDLSHNPLVQLTRDIFSNEFPLNSLNLGNCSLRKLEQHAFKSLTNLNELNLERNQLNPADIQTLD 912

  Fly   243 LTNVQNLVLEGSSLS---SLVINGG---------------------------------------- 264
            :.|::.|:|..::.|   |:.|..|
  Fly   913 IPNLRRLLLSHNNFSYAGSVGIMAGMLDRLRSLQQLSMSNCSLGQIPDLLFAKNTNLVRLDLCDN 977

  Fly   265 ---------------FIKLQAGNNELN---HLQVGNKSSVIEMDLHGNLLNGNDTAALLRGMWNL 311
                           |.:|:...|||:   |:.:.|.|::..:||..|.|...|... |.|..||
  Fly   978 RLTQINRNIFSGLNVFKELRLCRNELSDFPHIALYNLSTLESLDLARNQLASIDFFK-LSGTLNL 1041

  Fly   312 QRLDLSKNRIEALPQHGSGLDASGTQELLILPSLKFLNLANNQLVRLPPESPILSSRLSYLDLSH 376
            ::|.|..|:|.||    ||.:|      :.|..|..::|:.|.|:.||......|..|..:.||:
  Fly  1042 RQLILRDNKITAL----SGFNA------VNLTQLDSVDLSGNLLLSLPANFLRHSINLQKVHLSN 1096

  Fly   377 NLMLTLDVAILRSLSV--LKGLYVEGNRLNTINYQKLHEEHPDLSEL 421
            |..|.:..:.|..:|:  |..|.:.||.:|.| |....|.:|.|.||
  Fly  1097 NRFLQIPSSALSDVSIPRLSWLNLTGNPINRI-YTVKEERYPYLKEL 1142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18249	NP_001163549.1	leucine-rich repeat	57..80	CDD:275380	6/22 (27%)
		LRR	105..433	CDD:443914	106/454 (23%)
		leucine-rich repeat	105..128	CDD:275380	5/22 (23%)
		leucine-rich repeat	129..152	CDD:275380	8/22 (36%)
		leucine-rich repeat	153..176	CDD:275380	7/22 (32%)
		leucine-rich repeat	177..200	CDD:275380	8/22 (36%)
		leucine-rich repeat	201..224	CDD:275380	8/22 (36%)
		leucine-rich repeat	225..258	CDD:275380	12/61 (20%)
		leucine-rich repeat	259..310	CDD:275380	17/108 (16%)
		leucine-rich repeat	311..344	CDD:275380	11/32 (34%)
		leucine-rich repeat	345..368	CDD:275380	7/22 (32%)
		leucine-rich repeat	369..390	CDD:275380	6/20 (30%)
		leucine-rich repeat	393..417	CDD:275380	8/23 (35%)
CG42346	NP_001036303.2	LRR	<301..606	CDD:443914
		leucine-rich repeat	303..325	CDD:275380
		leucine-rich repeat	327..350	CDD:275380
		leucine-rich repeat	351..461	CDD:275380
		leucine-rich repeat	399..422	CDD:275380
		leucine-rich repeat	462..485	CDD:275380
		LRR	486..>736	CDD:443914	22/82 (27%)
		leucine-rich repeat	486..509	CDD:275380
		leucine-rich repeat	510..533	CDD:275380
		leucine-rich repeat	534..556	CDD:275380
		leucine-rich repeat	557..580	CDD:275380
		leucine-rich repeat	581..604	CDD:275380
		leucine-rich repeat	605..628	CDD:275380
		PPP1R42	627..860	CDD:455733	50/206 (24%)
		leucine-rich repeat	629..652	CDD:275380
		leucine-rich repeat	653..676	CDD:275380	6/22 (27%)
		leucine-rich repeat	677..700	CDD:275380	4/22 (18%)
		leucine-rich repeat	701..748	CDD:275380	13/46 (28%)
		leucine-rich repeat	725..736	CDD:275378	4/10 (40%)
		leucine-rich repeat	749..772	CDD:275380	0/22 (0%)
		leucine-rich repeat	773..793	CDD:275380	0/19 (0%)
		leucine-rich repeat	821..844	CDD:275380	8/22 (36%)
		leucine-rich repeat	845..868	CDD:275380	8/22 (36%)
		LRR	869..1226	CDD:443914	68/286 (24%)
		leucine-rich repeat	869..892	CDD:275380	4/22 (18%)
		leucine-rich repeat	893..915	CDD:275380	4/21 (19%)
		leucine-rich repeat	916..944	CDD:275380	6/27 (22%)
		leucine-rich repeat	945..968	CDD:275380	0/22 (0%)
		leucine-rich repeat	969..992	CDD:275380	0/22 (0%)
		leucine-rich repeat	993..1014	CDD:275380	6/20 (30%)
		leucine-rich repeat	1017..1040	CDD:275380	7/23 (30%)
		leucine-rich repeat	1041..1064	CDD:275380	11/32 (34%)
		leucine-rich repeat	1089..1114	CDD:275380	7/24 (29%)
		leucine-rich repeat	1115..1162	CDD:275380	12/29 (41%)
		PPP1R42	1155..1317	CDD:455733
		leucine-rich repeat	1163..1186	CDD:275380
		leucine-rich repeat	1187..1210	CDD:275380
		leucine-rich repeat	1211..1233	CDD:275380
		leucine-rich repeat	1234..1257	CDD:275380
		leucine-rich repeat	1258..1279	CDD:275380
		leucine-rich repeat	1282..1306	CDD:275380