DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18249 and LOC1276943

DIOPT Version :10

Sequence 1:NP_001163549.1 Gene:CG18249 / 40964 FlyBaseID:FBgn0037553 Length:559 Species:Drosophila melanogaster
Sequence 2:XP_061507303.1 Gene:LOC1276943 / 1276943 VectorBaseID:AGAMI1_000227 Length:347 Species:Anopheles gambiae


Alignment Length:433 Identity:87/433 - (20%)
Similarity:142/433 - (32%) Gaps:136/433 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   155 LLGLQG--------NAIAEILSSTLDPLMELVHLDLSRN----ELTTLPQNIFAKNKKLQTLLLN 207
            ||.|.|        |....|::......:|.||||:|.|    :....|::        .|||:.
Mosquito    16 LLALTGCICRAQSKNFKCSIINEAGFCFIENVHLDVSTNGIGGDSIQFPRH--------PTLLIK 72

  Fly   208 GNPLRILMPDVLGSLPNLRLLDLGHAAELEVMTLNLTNVQNLVLEGSSLSSL-VINGGFIKLQ-- 269
            ...:.....|:...|.|.:.|.:          .|.|:::||.:..::|:.: |...|.::..  
Mosquito    73 SGAIPYFGKDIFALLGNTKQLHV----------YNQTSIRNLFIPVTNLTEINVQRNGLLEFDVE 127

  Fly   270 -AGNNELNHLQVGNKSSVIEMDLHGNLLNGNDTAALLRGMWNLQRLDLSKNRIE-------ALPQ 326
             ..|.||..|.:          :|..|:.   ....:|.:..|::|.|..|.:|       |...
Mosquito   128 PVENRELKMLSI----------VHNGLVT---VPRNIRFLVGLEKLYLYNNSLEYFDLEPLANAS 179

  Fly   327 HGSGLDASGTQELLILPSLKFLNLANNQLVRLPPESPILSSRLSYLDLSHNLMLTLDVAILRSLS 391
            |                |||.|::.:|.:..|...|.:...:|..|.||.               
Mosquito   180 H----------------SLKILSIYDNHIKTLDSRSALYFPKLQTLSLSK--------------- 213

  Fly   392 VLKGLYVEGNRLNTINYQKLHEEHPDLSELGLHDNPWSSGLYRKMFLYFTDRGVHLQARPQNRVL 456
                     |:|..:.|  ..|..|.::.:.|..|||:.|.......|...|.:        :|:
Mosquito   214 ---------NKLAFVPY--FEESFPAVTVVSLRKNPWNCGWLHTTMQYIEARKI--------QVV 259

  Fly   457 NKSSRVDIDWPPNEGQAEAQKMDPPGVTGIHPYWTLRDILAFVTLLVVMIILLMNLYHILEEEGC 521
            .|.:.....|                         :.:|....|:|..|..  .....|..|:..
Mosquito   260 RKDAACRDRW-------------------------ISEICCTYTVLDFMFD--RAAAQIRREQQL 297

  Fly   522 LRRFRHWRRS--RTLGQNTSTTRNSGRRLDEQD---SEQSSSE 559
            ||...|..|.  .|:.|..........:||:|.   ||:|.|:
Mosquito   298 LRNVTHENRRLVETVHQLADDLHRLQSQLDQQQQPASEKSISD 340

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18249NP_001163549.1 leucine-rich repeat 57..80 CDD:275380
LRR 105..433 CDD:443914 63/300 (21%)
leucine-rich repeat 105..128 CDD:275380
leucine-rich repeat 129..152 CDD:275380
leucine-rich repeat 153..176 CDD:275380 6/28 (21%)
leucine-rich repeat 177..200 CDD:275380 7/26 (27%)
leucine-rich repeat 201..224 CDD:275380 5/22 (23%)
leucine-rich repeat 225..258 CDD:275380 6/32 (19%)
leucine-rich repeat 259..310 CDD:275380 9/54 (17%)
leucine-rich repeat 311..344 CDD:275380 7/39 (18%)
leucine-rich repeat 345..368 CDD:275380 6/22 (27%)
leucine-rich repeat 369..390 CDD:275380 4/20 (20%)
leucine-rich repeat 393..417 CDD:275380 4/23 (17%)
LOC1276943XP_061507303.1 None
Blue background indicates that the domain is not in the aligned region.

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