Protein Alignment CG18249 and LOC1270056

DIOPT Version :10

• Sequence 1: NP_001163549.1
• Gene: CG18249 / 40964
• FlyBaseID: FBgn0037553
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_308718.5
• Gene: LOC1270056 / 1270056
• VectorBaseID: AGAMI1_004893
• Length: 571
• Species: Anopheles gambiae
• Alignment Length: 523
• Identity: 124/523 - (23%)
• Similarity: 208/523 - (39%)
• Gaps: 102/523 - (19%)

  Fly    59 ELHLRNCSRQSITWLVLQLTPGLRTLVIRNCATYHISKESLRP--------------------VE 103
            |..:|:|:...:|             |:.:.|....|.|..||                    ..
Mosquito    35 EYTVRHCTLHGVT-------------VVHDAADIDFSSEYPRPYWFDFQHSQMDEIPRALFTTFP 86

  Fly   104 NLTSLQMQGTSLGVLRDQIFNAVPRLEILQLSQNFIHTVHVAAFQGLSKLRLLGLQGNAIAEILS 168
            .:.::..:.|.:..:....|....:|..|.|.:|.:.:::...|:|..:|..|.|..|.:.|:.:
Mosquito    87 EMQTIDFRETGIENINKFTFENAKQLRHLFLRRNKLTSLNNFIFKGCDRLEWLDLSHNQLQEVRN 151

  Fly   169 STLDPLMELVHLDLSRNELTTLPQNIFAKNKKLQTLLLNGNPLRILMPDVLGSLPNLRLLDLGHA 233
            .|...:..|..|||:.|.||.||:.:|.:..:|..|.||.|.|.:              ||....
Mosquito   152 KTFHDIRTLTRLDLNHNRLTVLPEEVFWELPELAHLSLNDNQLVV--------------LDRETF 202

  Fly   234 AELEVMTLNLT--------------NVQNLVLEGSSLSSLVINGGFIKLQAGNNELNHLQVGNKS 284
            ....:::|||.              :.|.:.|.|:.|:|:.|....:::...:|.|..:.|...:
Mosquito   203 FHSRIVSLNLNFNRLREVHMVDRFQSWQRVHLRGNQLTSVEIPPVPVEIDVSHNNLTTILVSYSN 267

  Fly   285 SVIE-MDLHGNLLNGNDTAALLRGMWNLQRLDLSKNRIEALPQHGSGLDASGTQELLILPSLKFL 348
            .::| :||..||.......:.|.   .|..||:|.|.:::||          ....|.:..|..|
Mosquito   268 ILVESLDLSHNLFADISNVSALN---FLHTLDVSFNALQSLP----------LTTFLKMKQLARL 319

  Fly   349 NLANNQLVRLPPESPILSSRLSYLDLSHNLMLTLDVAILRSLSVLKGLYVEGNRLNTINYQKLHE 413
            ||....|..|........|.|::||:|.|.:.|:|:.:|.:.:.|:.|:::||.|.::.|.:|..
Mosquito   320 NLEATNLTTLVHGLFSQQSNLTWLDVSFNRLQTIDLTVLTAAAKLEHLHIDGNNLTSVGYGRLPA 384

  Fly   414 EHPDLSELGLHDNPWSSGLYRKMFLYFTDRGVH------LQARPQNRVLNKSSRVDIDWPPNEG- 471
            ..|.|:.|||..|.|:..       |..|. ||      :...||     ||....:|....:|
Mosquito   385 MFPSLTYLGLFANAWNCS-------YLVDL-VHFCRQHSINVAPQ-----KSYGTTLDASNVQGI 436

  Fly   472 -QAEAQKMDPPGVTGI-HPYWTLRDI--LAFVTLLVVMIILLMNLYHILEEEGCLRRFRHWRRSR 532
             ...:|....|.||.| ||..|....  |:...||.:|..:......:::|   :.|..|.|.:.
Mosquito   437 YCKSSQSTVLPVVTPIEHPIDTAPPSAELSIDRLLEMMQEMNKTTEQLVQE---MMRALHQRATG 498

  Fly   533 TLG 535
            .:|
Mosquito   499 AIG 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18249	NP_001163549.1	leucine-rich repeat	57..80	CDD:275380	4/20 (20%)
		LRR	105..433	CDD:443914	87/342 (25%)
		leucine-rich repeat	105..128	CDD:275380	2/22 (9%)
		leucine-rich repeat	129..152	CDD:275380	6/22 (27%)
		leucine-rich repeat	153..176	CDD:275380	6/22 (27%)
		leucine-rich repeat	177..200	CDD:275380	10/22 (45%)
		leucine-rich repeat	201..224	CDD:275380	6/22 (27%)
		leucine-rich repeat	225..258	CDD:275380	9/46 (20%)
		leucine-rich repeat	259..310	CDD:275380	10/51 (20%)
		leucine-rich repeat	311..344	CDD:275380	8/32 (25%)
		leucine-rich repeat	345..368	CDD:275380	6/22 (27%)
		leucine-rich repeat	369..390	CDD:275380	8/20 (40%)
		leucine-rich repeat	393..417	CDD:275380	7/23 (30%)
LOC1270056	XP_308718.5	None