Protein Alignment CG18249 and LOC1270053

DIOPT Version :10

• Sequence 1: NP_001163549.1
• Gene: CG18249 / 40964
• FlyBaseID: FBgn0037553
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_308715.5
• Gene: LOC1270053 / 1270053
• VectorBaseID: AGAMI1_004829
• Length: 937
• Species: Anopheles gambiae
• Alignment Length: 461
• Identity: 107/461 - (23%)
• Similarity: 175/461 - (37%)
• Gaps: 111/461 - (24%)

  Fly    36 PDSFCSLSD-----------RPVAYSATPALQ-LRELHLRNCSRQSI----TWLVLQLTPGLRTL 84
            |::|.||..           ..|...|..||. |:.|.:.|...:|:    .:|.|   ..|::|
Mosquito    82 PNAFASLKALTNLNLDNNLFATVPREALSALSTLKTLSIANNLLESLDDGDVFLSL---ARLQSL 143

  Fly    85 VIRNCATYHISKESLRPVENLTSLQMQGTSLGVLRDQIFNAVPRLEILQLSQNFIHTVHVAAFQG 149
            .:.:...:.:..:|...:..|..|.:....|......|.....:|::|.||.|:::.::|:.|..
Mosquito   144 SLDSNLIHQLHPQSFARLAELKLLNVSWNRLTAFESIILPPENQLQVLDLSYNYVNLLNVSTFHR 208

  Fly   150 LSKLRLLGLQGNAIAEILSSTLDPLMELVHLDLSRNELTTLPQNIFAKNKKLQTLLLNGNPLRIL 214
            |..||.|.|.||....:..:|...|..|..||||.|...:||..:|..|:||..|.|..|
Mosquito   209 LPALRELSLAGNQFESLHPNTFATLRHLSRLDLSDNFFQSLPPRLFTSNRKLAELNLAAN----- 268

  Fly   215 MPDVLGSLPNLRLLDLGHAAELEVMTLNLTNVQNLVL-EGSSLSSLVINGGFIK------LQAG- 271
               :|.:||......|.|...|.:....||.:...:. |....:.|.:.|..|:      |||.
Mosquito   269 ---LLDTLPGDLFAGLKHLTALNLRNNRLTELPATIFREQPPFAQLALEGNRIERFPSDWLQASA 330

  Fly   272 -----NNELNHLQ----------------VGNKSSVIEMDLHGNLLNGNDTAALLRGMWNLQRLD 315
                 ||.|..|:                .||:.:.:|.|             :.|.:..|:.|.
Mosquito   331 DLLLQNNRLAGLRKFAPSANGTVVRRLFLYGNEIATVEQD-------------VFRAVPKLETLY 382

  Fly   316 LSKNRIEAL------PQHGSGLDASGTQELLILPSLKFLNLANNQLVRLPPESPILSSRLSYLDL 374
            |..|||:.|      ..|                .|:.:.|::|:|..|...:....:||..:||
Mosquito   383 LDYNRIDELSPMVFHTNH----------------ELQHVTLSHNRLAVLRTNTFAGLARLHSVDL 431

  Fly   375 SHNLMLTLDVAILRSLSVLKGLYVEGNRLNTINYQKLHEEHPDLSELGLHDNPWSSGLYRKMFLY 439
            |:|.:..::.::... |.::.|.:.||||.|:                   :.||....|.::||
Mosquito   432 SYNRLAAIEESVFHG-SPVEYLNLNGNRLRTL-------------------DEWSFSGTRLLYLY 476

  Fly   440 FTDRGV 445
            .....:
Mosquito   477 VDSNAI 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18249	NP_001163549.1	leucine-rich repeat	57..80	CDD:275380	6/26 (23%)
		LRR	105..433	CDD:443914	87/362 (24%)
		leucine-rich repeat	105..128	CDD:275380	4/22 (18%)
		leucine-rich repeat	129..152	CDD:275380	8/22 (36%)
		leucine-rich repeat	153..176	CDD:275380	8/22 (36%)
		leucine-rich repeat	177..200	CDD:275380	10/22 (45%)
		leucine-rich repeat	201..224	CDD:275380	6/22 (27%)
		leucine-rich repeat	225..258	CDD:275380	6/33 (18%)
		leucine-rich repeat	259..310	CDD:275380	15/78 (19%)
		leucine-rich repeat	311..344	CDD:275380	8/38 (21%)
		leucine-rich repeat	345..368	CDD:275380	5/22 (23%)
		leucine-rich repeat	369..390	CDD:275380	5/20 (25%)
		leucine-rich repeat	393..417	CDD:275380	6/23 (26%)
LOC1270053	XP_308715.5	None