DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18249 and LOC101882092

DIOPT Version :9

Sequence 1:	NP_001163549.1	Gene:	CG18249 / 40964	FlyBaseID:	FBgn0037553	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	XP_005164829.1	Gene:	LOC101882092 / 101882092	-ID:	-	Length:	678	Species:	Danio rerio

Alignment Length:	412	Identity:	109/412 - (26%)
Similarity:	170/412 - (41%)	Gaps:	89/412 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 CPDSFCSLSDRPVAYSATPALQL--------RELHLRNCSRQSITWLVLQLTPGLRTLVIR-NCA 90
            || |.||...|.|..|....:::        |.:.|.|....||...:|.....:..||:| |..
Zfish   307 CP-SECSCYGRVVQCSDKHLVKIPYGIPYNSRYILLMNNKIDSIQLNLLSQYDSMEFLVLRNNRL 370

  Fly    91 TYHISKESLRPVENLTSLQMQGTSLGVLRDQIFNAVPRLEILQLSQNFIHTVHVAAFQGLSKLRL 155
            |....|::...::.|..|.::   ..:||....:....||.|:|..|.|..:..|||:....|::
Zfish   371 TDSAVKKAFEGIQRLKRLYVE---RNLLRSIPTDLPATLEELRLDWNQISAMSNAAFERCPSLQI 432

  Fly   156 LGLQGNAIAEILSSTLDPLMELVHLDLSRNELTTLPQNIFAKNKKLQTLLLNGNPLRILMPDVLG 220
            |.|..|.:..|....|.||..|..|.||.|:|.::|..:   ...|:.|.|.||.::.|..|:..
Zfish   433 LSLSNNTLLTIPPGVLLPLGSLRTLTLSYNQLASVPMQL---PLSLRELYLRGNRIQRLQGDMFW 494

  Fly   221 SLPNLRLLD----------LGHAAELEVMTLNLTNVQNLVLEGS-----------SLSSLVINGG 264
            ....|::||          ||.||     .||.|.:::|.|||:           ::.:|.:.|.
Zfish   495 GESELQILDLSLNRLTDKGLGKAA-----LLNATGLESLNLEGNLLKRVPRHLPHTIKTLNLEGN 554

  Fly   265 FIKLQAGNNELNHLQVGNKSSVIEMDLHGNL-LNGNDTAALLRGMWN----LQRLDLSKNRIEAL 324
            ||           |.: .|.:.:.|....:| |..|..|.:..|.:.    |.:||:|.|.:|.:
Zfish   555 FI-----------LSI-TKDAFVSMPQLEHLGLARNKIAKVALGAFRVLPLLHQLDMSYNALEQV 607

  Fly   325 PQHGSGLDASGTQELLILPSLKFLNLANNQLVRLP------------PESPILSSRLSY--LDLS 375
            |:          |..|.|.|..|:   :|.:..:|            |.|.::..:|.|  :||.
Zfish   608 PR----------QLPLWLHSATFM---HNNIRSIPRDAFCWGRDNVSPLSRLVKVQLEYNMIDLG 659

  Fly   376 HNLMLTLDVAILRSLSVLKGLY 397
            |  :.||....||...|:: ||
Zfish   660 H--LDTLAFRCLRGFQVVE-LY 678

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18249	NP_001163549.1	leucine-rich repeat	57..80	CDD:275380	6/30 (20%)
		LRR_8	104..163	CDD:290566	17/58 (29%)
		leucine-rich repeat	105..128	CDD:275380	4/22 (18%)
		LRR_RI	107..438	CDD:238064	88/331 (27%)
		leucine-rich repeat	129..152	CDD:275380	9/22 (41%)
		leucine-rich repeat	153..176	CDD:275380	8/22 (36%)
		LRR_8	176..232	CDD:290566	18/65 (28%)
		leucine-rich repeat	177..200	CDD:275380	7/22 (32%)
		leucine-rich repeat	201..224	CDD:275380	7/22 (32%)
		leucine-rich repeat	225..258	CDD:275380	14/53 (26%)
		leucine-rich repeat	259..310	CDD:275380	12/51 (24%)
		leucine-rich repeat	311..344	CDD:275380	10/32 (31%)
		LRR_8	343..403	CDD:290566	18/69 (26%)
		leucine-rich repeat	345..368	CDD:275380	5/34 (15%)
		leucine-rich repeat	369..390	CDD:275380	9/22 (41%)
		leucine-rich repeat	393..417	CDD:275380	2/5 (40%)
LOC101882092	XP_005164829.1	LRRNT	307..335	CDD:214470	8/28 (29%)
		leucine-rich repeat	316..334	CDD:275380	3/17 (18%)
		leucine-rich repeat	337..359	CDD:275380	6/21 (29%)
		LRR_RI	360..596	CDD:238064	68/258 (26%)
		leucine-rich repeat	360..384	CDD:275380	6/23 (26%)
		leucine-rich repeat	385..404	CDD:275380	4/21 (19%)
		LRR_8	405..464	CDD:290566	22/58 (38%)
		leucine-rich repeat	406..429	CDD:275380	9/22 (41%)
		leucine-rich repeat	430..453	CDD:275380	8/22 (36%)
		leucine-rich repeat	454..474	CDD:275380	7/22 (32%)
		LRR_8	474..535	CDD:290566	21/65 (32%)
		leucine-rich repeat	475..498	CDD:275380	7/22 (32%)
		leucine-rich repeat	499..524	CDD:275380	9/29 (31%)
		leucine-rich repeat	525..544	CDD:275380	4/18 (22%)
		leucine-rich repeat	546..569	CDD:275380	7/34 (21%)
		LRR_8	547..604	CDD:290566	17/68 (25%)
		leucine-rich repeat	570..593	CDD:275380	5/22 (23%)
		leucine-rich repeat	618..645	CDD:275380	4/29 (14%)
		leucine-rich repeat	646..671	CDD:275380	8/26 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910