DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7800 and RLP35

DIOPT Version :9

Sequence 1:	NP_649770.1	Gene:	CG7800 / 40963	FlyBaseID:	FBgn0037552	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001319521.1	Gene:	RLP35 / 820279	AraportID:	AT3G11080	Length:	943	Species:	Arabidopsis thaliana

Alignment Length:	623	Identity:	135/623 - (21%)
Similarity:	192/623 - (30%)	Gaps:	219/623 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LGRPDLEDYC------------------NDSYCHLLGRSRTFSDKKATKLTEFHMDSCEKKVLKL 61
            :|:|...|||                  |...|:..|.:   .|.|:.::.|..: ||.......
plant    55 IGKPSSNDYCYRNNSRVSPHPTTESWRNNSDCCNWEGIT---CDTKSGEVIELDL-SCSWLYGSF 115

  Fly    62 MPNLRTLELENCDSPDFTMNDLN--------QLPYLTSLQLRRGNLLGLHDEHFSKWPNMKILML 118
            ..|.....|:|....|.|.|||:        .|.:||||.|.....|||..........:..|.|
plant   116 HSNSSLFRLQNLRVLDLTQNDLDGEIPSSIGNLSHLTSLHLSYNQFLGLIPSSIENLSRLTSLHL 180

  Fly   119 GGNNIT----------------RLSNECFKG--------LAQLWLLSLPGNGIQG---------- 149
            ..|..:                .||:..|.|        |:.|..||||.|...|
plant   181 SSNQFSGQIPSSIGNLSHLTSLELSSNQFSGQIPSSIGNLSNLTFLSLPSNDFFGQIPSSIGNLA 245

  Fly   150 ----------------------------------------------------------------- 149

plant   246 RLTYLYLSYNNFVGEIPSSFGNLNQLIVLQVDSNKLSGNVPISLLNLTRLSALLLSHNQFTGTIP 310

  Fly   150 ----------------------LPWDVFQNLPELLHLDLSGNRIE-TLHENIFTGVPKLEMLLLN 191
                                  ||..:| |:|.|:.||||.|::. |||....:....|:.|::.
plant   311 NNISLLSNLMDFEASNNAFTGTLPSSLF-NIPPLIRLDLSDNQLNGTLHFGNISSPSNLQYLIIG 374

  Fly   192 GNPLTWIAPTSLKSLSNLRLLDMSN----CGP-----------LPDLSLPGAHTLILDNSGV--- 238
            .|......|.||....||.|.|:|:    |.|           |.||.|....|..:|.:.:
plant   375 SNNFIGTIPRSLSRFVNLTLFDLSHLNTQCRPVDFSIFSHLKSLDDLRLSYLTTTTIDLNDILPY 439

  Fly   239 ----QRLDILGSVHKLQARKNHITEIKLPDKSSVIELDLHSNLLTATDIPKLLTGMWRLQRLDLS 299
                :.|||.|:   |.:..|..:....|...|:..|.|..  ...||.|::|.....|..||:|
plant   440 FKTLRSLDISGN---LVSATNKSSVSSDPPSQSIQSLYLSG--CGITDFPEILRTQHELGFLDVS 499

  Fly   300 ENIIGIYAAAGSDNTSELFILPNLMYMNLSANRL------TRLHFDSPIPWERLTHLDASYNRIY 358
            .|.|      .......|:.||||.|:|||.|..      ::.|..|.:....:.||.||.|...
plant   500 NNKI------KGQVPGWLWTLPNLFYLNLSNNTFISFESSSKKHGLSSVRKPSMIHLFASNNNFT 558

  Fly   359 APAKVGIDEAFNLQSLHLEGNYINN-------------FELT----------PWKPHPSLKEVAL 400
            ......|....:|.:|.|..|..|.             |.|.          |.....||:.:.:
plant   559 GKIPSFICGLRSLNTLDLSENNYNGSIPRCMEKLKSTLFVLNLRQNNLSGGLPKHIFESLRSLDV 623

  Fly   401 YDNKFQPKGYKNITKFFNEIGVNVLEKTQYSQSNNTTP 438
            ..|....|..:::.:|.|...:||    :.::.|:|.|
plant   624 GHNLLVGKLPRSLIRFSNLEVLNV----ESNRINDTFP 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7800	NP_649770.1	leucine-rich repeat	46..64	CDD:275380	3/17 (18%)
		leucine-rich repeat	65..85	CDD:275380	7/27 (26%)
		LRR_8	87..147	CDD:290566	22/83 (27%)
		leucine-rich repeat	89..112	CDD:275380	8/22 (36%)
		leucine-rich repeat	113..136	CDD:275380	8/46 (17%)
		LRR_RI	<131..334	CDD:238064	73/336 (22%)
		leucine-rich repeat	137..160	CDD:275380	11/119 (9%)
		LRR_8	140..195	CDD:290566	23/152 (15%)
		leucine-rich repeat	161..184	CDD:275380	9/23 (39%)
		leucine-rich repeat	185..208	CDD:275380	6/22 (27%)
		leucine-rich repeat	209..246	CDD:275380	15/58 (26%)
		leucine-rich repeat	247..267	CDD:275380	3/19 (16%)
		leucine-rich repeat	268..292	CDD:275380	6/23 (26%)
		leucine-rich repeat	293..322	CDD:275380	8/28 (29%)
		leucine-rich repeat	395..406	CDD:275378	2/10 (20%)
RLP35	NP_001319521.1	LRRNT_2	39..95	CDD:311940	8/42 (19%)
		PLN00113	79..>658	CDD:331614	130/599 (22%)
		leucine-rich repeat	103..123	CDD:275380	4/20 (20%)
		leucine-rich repeat	127..150	CDD:275380	6/22 (27%)
		leucine-rich repeat	151..174	CDD:275380	8/22 (36%)
		leucine-rich repeat	175..198	CDD:275380	3/22 (14%)
		leucine-rich repeat	199..222	CDD:275380	5/22 (23%)
		leucine-rich repeat	223..246	CDD:275380	7/22 (32%)
		leucine-rich repeat	247..270	CDD:275380	0/22 (0%)
		leucine-rich repeat	271..294	CDD:275380	0/22 (0%)
		leucine-rich repeat	295..318	CDD:275380	0/22 (0%)
		leucine-rich repeat	319..337	CDD:275380	2/17 (12%)
		leucine-rich repeat	343..367	CDD:275380	9/23 (39%)
		leucine-rich repeat	368..388	CDD:275380	6/19 (32%)
		leucine-rich repeat	392..417	CDD:275380	6/24 (25%)
		leucine-rich repeat	443..469	CDD:275380	7/28 (25%)
		leucine-rich repeat	470..492	CDD:275380	6/23 (26%)
		leucine-rich repeat	493..516	CDD:275380	8/28 (29%)
		leucine-rich repeat	517..541	CDD:275380	7/23 (30%)
		leucine-rich repeat	542..570	CDD:275380	6/27 (22%)
		leucine-rich repeat	571..594	CDD:275380	5/22 (23%)
		leucine-rich repeat	596..617	CDD:275380	3/20 (15%)
		leucine-rich repeat	618..641	CDD:275380	4/22 (18%)
		LRR_8	640..698	CDD:316378	6/22 (27%)
		leucine-rich repeat	642..665	CDD:275380	5/20 (25%)
		leucine-rich repeat	716..803	CDD:275380
		PLN00113	<758..864	CDD:331614
		leucine-rich repeat	804..825	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000