Protein Alignment CG7800 and Igfals

DIOPT Version :10

• Sequence 1: NP_649770.1
• Gene: CG7800 / 40963
• FlyBaseID: FBgn0037552
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_445781.3
• Gene: Igfals / 79438
• RGDID: 68429
• Length: 603
• Species: Rattus norvegicus
• Alignment Length: 592
• Identity: 142/592 - (23%)
• Similarity: 215/592 - (36%)
• Gaps: 203/592 - (34%)

  Fly     5 IIALLASVSALGRPDLEDYCNDSYCHLLGRSRTFS----------------DKKATKLTEFHMDS 53
            ::.|||...|||.           |||.|.....|                |....:|:.|
  Rat    10 LVVLLAFWVALGP-----------CHLQGTDPGASADAEGPQCPVACTCSHDDYTDELSVF---- 59

  Fly    54 CEKKVLKLMP---------------NLRTL---ELENCDSPDFTMNDLN-QLPYLTSLQ----LR 95
            |..|.|..:|               ||.::   ..:|..|.||    || |..:|.||:    |.
  Rat    60 CSSKNLTHLPDDIPVSTRALWLDGNNLSSIPSAAFQNLSSLDF----LNLQGSWLRSLEPQALLG 120

  Fly    96 RGNLLGLHDEH----------FSKWPNMKILMLGGNNITRLSNECFKGLAQLWLLSLPGNGIQGL 150
            ..||..||.|.          |:..|::..|.|..|.:.||....|:||:.||.|:|..|.:..|
  Rat   121 LQNLYHLHLERNRLRNLAVGLFTHTPSLASLSLSSNLLGRLEEGLFQGLSHLWDLNLGWNSLVVL 185

  Fly   151 PWDVFQ------------------------NLPELLHLDLSGNRIETLHENIFTGVPKLEMLLLN 191
            |..|||                        .|.||..||||.|.:.::..|:|..:|:|:.|.|:
  Rat   186 PDTVFQGLGNLHELVLAGNKLTYLQPALFCGLGELRELDLSRNALRSVKANVFVHLPRLQKLYLD 250

  Fly   192 GNPLTWIAPTSLKSLSNLRLLDMSN---CGPLPDL--SLPGAHTLILDNSGVQRL------DI-- 243
            .|.:|.:||.:...:..||.||:|:   .|.:.|.  .|.|.|.|.|.::.:..|      |:
  Rat   251 RNLITAVAPRAFLGMKALRWLDLSHNRVAGLMEDTFPGLLGLHVLRLAHNAIASLRPRTFKDLHF 315

  Fly   244 ---------------------LGSVHKLQARKNHITEIKLPDKS---SVIELDLHSNLLTATDIP 284
                                 ||.:..|....|.|||:::...|   :|..::|..|.|.:  :|
  Rat   316 LEELQLGHNRIRQLGERTFEGLGQLEVLTLNDNQITEVRVGAFSGLFNVAVMNLSGNCLRS--LP 378

  Fly   285 -KLLTGMWRLQRLDLSENIIG---IYAAAGSDNTSELFI---------------LPNLMYMNLSA 330
             ::..|:.:|..|.|..:.:|   ::..||......||:               |..|:.::|:.
  Rat   379 ERVFQGLDKLHSLHLEHSCLGHVRLHTFAGLSGLRRLFLRDNSISSIEEQSLAGLSELLELDLTT 443

  Fly   331 NRLTRL---------HFDSPI---------------PWERLTHLDASYNRIYAPAKVGIDEAFNL 371
            ||||.|         |.:..:               |.:|...||.|:|.:...|:........|
  Rat   444 NRLTHLPRQLFQGLGHLEYLLLSYNQLTTLSAEVLGPLQRAFWLDISHNHLETLAEGLFSSLGRL 508

  Fly   372 QSLHLEGNYINNF-----------ELTPWK---PHPSLKEVALYDNKFQPK-------------- 408
            :.|.|..|.:..|           :..||.   |..:|::.||.:....|:
  Rat   509 RYLSLRNNSLQTFSPQPGLERLWLDANPWDCSCPLKALRDFALQNPGVVPRFVQTVCEGDDCQPV 573

  Fly   409 -GYKNIT 414
             .|.|||
  Rat   574 YTYNNIT 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7800	NP_649770.1	leucine-rich repeat	46..64	CDD:275380	6/32 (19%)
		leucine-rich repeat	65..85	CDD:275380	7/23 (30%)
		LRR	68..482	CDD:443914	122/498 (24%)
		leucine-rich repeat	89..112	CDD:275380	10/36 (28%)
		leucine-rich repeat	113..136	CDD:275380	8/22 (36%)
		leucine-rich repeat	137..160	CDD:275380	11/46 (24%)
		leucine-rich repeat	161..184	CDD:275380	8/22 (36%)
		leucine-rich repeat	185..208	CDD:275380	7/22 (32%)
		leucine-rich repeat	209..246	CDD:275380	15/70 (21%)
		leucine-rich repeat	247..267	CDD:275380	6/22 (27%)
		leucine-rich repeat	268..292	CDD:275380	6/24 (25%)
		leucine-rich repeat	293..322	CDD:275380	9/46 (20%)
		leucine-rich repeat	395..406	CDD:275378	3/10 (30%)
Igfals	NP_445781.3	LRRNT	40..78	CDD:214470	7/41 (17%)
		leucine-rich repeat	57..75	CDD:275380	5/21 (24%)
		LRR 1	75..96		2/20 (10%)
		leucine-rich repeat	79..99	CDD:275380	3/19 (16%)
		LRR	85..476	CDD:443914	101/396 (26%)
		LRR 2	99..120		9/24 (38%)
		leucine-rich repeat	103..123	CDD:275380	7/19 (37%)
		LRR 3	123..144		6/20 (30%)
		LRR 4	147..168		6/20 (30%)
		LRR 5	171..192		9/20 (45%)
		leucine-rich repeat	175..195	CDD:275380	8/19 (42%)
		LRR 6	195..216		0/20 (0%)
		leucine-rich repeat	196..219	CDD:275380	1/22 (5%)
		LRR 7	219..240		9/20 (45%)
		leucine-rich repeat	220..243	CDD:275380	8/22 (36%)
		LRR 8	243..264		7/20 (35%)
		leucine-rich repeat	244..267	CDD:275380	7/22 (32%)
		LRR 9	267..288		7/20 (35%)
		leucine-rich repeat	268..291	CDD:275380	8/22 (36%)
		LRR 10	291..312		5/20 (25%)
		leucine-rich repeat	292..315	CDD:275380	5/22 (23%)
		LRR 11	315..336		0/20 (0%)
		leucine-rich repeat	316..339	CDD:275380	1/22 (5%)
		LRR 12	339..360		5/20 (25%)
		leucine-rich repeat	340..363	CDD:275380	6/22 (27%)
		LRR 13	363..384		5/22 (23%)
		leucine-rich repeat	364..387	CDD:275380	6/24 (25%)
		LRR 14	387..408		4/20 (20%)
		leucine-rich repeat	388..411	CDD:275380	6/22 (27%)
		LRR 15	411..432		2/20 (10%)
		leucine-rich repeat	412..435	CDD:275380	3/22 (14%)
		LRR 16	435..456		7/20 (35%)
		leucine-rich repeat	436..459	CDD:275380	7/22 (32%)
		LRR 17	459..480		1/20 (5%)
		leucine-rich repeat	460..481	CDD:275380	0/20 (0%)
		LRR 18	483..504		6/20 (30%)
		leucine-rich repeat	484..507	CDD:275380	5/22 (23%)
		LRR_8	486..536	CDD:404697	10/49 (20%)
		LRR 19	507..528		5/20 (25%)
		LRRCT	535..578	CDD:214507	8/42 (19%)