DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7800 and lrrc4ba

DIOPT Version :9

Sequence 1:NP_649770.1 Gene:CG7800 / 40963 FlyBaseID:FBgn0037552 Length:533 Species:Drosophila melanogaster
Sequence 2:XP_021329717.1 Gene:lrrc4ba / 556747 ZFINID:ZDB-GENE-080327-25 Length:729 Species:Danio rerio


Alignment Length:565 Identity:127/565 - (22%)
Similarity:209/565 - (36%) Gaps:113/565 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    53 SCEKKVLKLMPNLRTLELENCDSPDFTMNDLNQLPYLTSLQLRRGNLLGLHDEHFSKWPNMKILM 117
            ||..:..:::...:.||    :.||   |..|...|   |.|:...:..:..:.|....:::||.
Zfish    45 SCSNQASRVICARQHLE----EVPD---NISNNTRY---LNLQENTIQVIKSDTFKHLRHLEILQ 99

  Fly   118 LGGNNITRLSNECFKGLAQLWLLSLPGNGIQGLPWDVFQNLPELLHLDLSGNRIETLHENIFTGV 182
            |..|.|.::....|.||..|..|.|..|.:..:|...|:.|.:|..|.|..|.||||....|..|
Zfish   100 LSKNQIRQIEVGAFNGLPNLNTLELFDNRLTLVPSQAFEYLSKLRELWLRNNPIETLPGYAFHRV 164

  Fly   183 PKLEMLLLNG-NPLTWIAPTSLKSLSNLRLLDMSNCG-----------PLPDLSLPGAHTLILDN 235
            |.|..|.|.. ..|.:|:..:...|.|||.|::..||           .|.:|.|.|....|:..
Zfish   165 PSLRRLDLGELKKLDYISDAAFVGLINLRYLNLGMCGLKDIPNLTPLVRLEELELSGNRLEIIRP 229

  Fly   236 SGVQRLDILGSVHKLQARKNHITEIKLPDKSSVIELDLHSNLLTATDIP-KLLTGMWRLQRLDLS 299
            ...|.|:.|..:..:.::.:.|......|..::.||:|..|.|.:  :| .|.|.:.:|:|:.|:
Zfish   230 GSFQGLESLRKLWLMHSQMSVIERNAFDDLKNLEELNLSHNSLHS--LPHDLFTPLQKLERVHLN 292

  Fly   300 ENIIGIYAAAGSDNTSELFI---LPNLMYMNLSANRLTRLHFDSPIPWERLTHLDASYNRIYAPA 361
            .|       ....|...|::   |...:..|.:.  ..|.|....:..:.:..||.|:...|||.
Zfish   293 HN-------PWVCNCDVLWLSWWLKETVPSNTTC--CARCHAPPYLKGKYIGELDQSHFTCYAPV 348

  Fly   362 KV------GIDEAFNLQSLHLEGNYINNFE-LTP---WKPHPS--LKEVALYDNKFQPKGYKNIT 414
            .|      .:.|....:.....|..:.:.. :||   ...|.|  ::...|:|...   .:.|:|
Zfish   349 IVEPPTDLNVTEGMAAELKCRTGTSMTSVNWITPNGTLMTHGSYRVRISVLHDGTL---NFTNVT 410

  Fly   415 -----------------------------------KFFNEIGVNVLEKTQYSQS-----NNT--- 436
                                               .:|..:.|..:|.|....|     |.|   
Zfish   411 LRDTGQYTCMVTNSAGNTTATAVLNVTAADVSVNYTYFTTVTVETVETTGEEDSALRTFNETFIH 475

  Fly   437 ----TPT---CKPCIPDARDFPTSI---SADTNQTIDTKVNPLSNDTYQWNVWNVLMLVSLIVSL 491
                ||:   ....:|.... ..||   |:....|..|...|:|..:|...:.:|:....:|:..
Zfish   476 IPGPTPSGHLWHEVVPTTAS-SLSIFGSSSSPRATKPTFTVPISEPSYPSGLDDVMKTTKIIIGC 539

  Fly   492 FV-----NSFLIVKLIRLRGRNQFTQSSSVPAIIEMFSNESDDEI 531
            ||     .:.::|...:||.::|..:.......||:.:.|  |||
Zfish   540 FVAITFMAAVMLVVFYKLRKQHQLHKHHGPARAIEIINVE--DEI 582

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7800NP_649770.1 leucine-rich repeat 46..64 CDD:275380 2/10 (20%)
leucine-rich repeat 65..85 CDD:275380 5/19 (26%)
LRR_8 87..147 CDD:290566 16/59 (27%)
leucine-rich repeat 89..112 CDD:275380 3/22 (14%)
leucine-rich repeat 113..136 CDD:275380 8/22 (36%)
LRR_RI <131..334 CDD:238064 59/218 (27%)
leucine-rich repeat 137..160 CDD:275380 7/22 (32%)
LRR_8 140..195 CDD:290566 20/55 (36%)
leucine-rich repeat 161..184 CDD:275380 10/22 (45%)
leucine-rich repeat 185..208 CDD:275380 6/23 (26%)
leucine-rich repeat 209..246 CDD:275380 13/47 (28%)
leucine-rich repeat 247..267 CDD:275380 2/19 (11%)
leucine-rich repeat 268..292 CDD:275380 8/24 (33%)
leucine-rich repeat 293..322 CDD:275380 7/31 (23%)
leucine-rich repeat 395..406 CDD:275378 2/10 (20%)
lrrc4baXP_021329717.1 LRR <60..280 CDD:227223 64/231 (28%)
leucine-rich repeat 71..94 CDD:275380 4/25 (16%)
leucine-rich repeat 95..118 CDD:275380 8/22 (36%)
leucine-rich repeat 119..142 CDD:275380 7/22 (32%)
leucine-rich repeat 143..166 CDD:275380 10/22 (45%)
leucine-rich repeat 167..191 CDD:275380 6/23 (26%)
leucine-rich repeat 192..213 CDD:275380 5/20 (25%)
leucine-rich repeat 214..237 CDD:275380 7/22 (32%)
leucine-rich repeat 238..261 CDD:275380 3/22 (14%)
leucine-rich repeat 262..283 CDD:275380 8/22 (36%)
TPKR_C2 294..344 CDD:326558 10/58 (17%)
I-set 347..436 CDD:333254 12/91 (13%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.000

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