Protein Alignment CG7800 and Tollo

DIOPT Version :10

• Sequence 1: NP_649770.1
• Gene: CG7800 / 40963
• FlyBaseID: FBgn0037552
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_524757.1
• Gene: Tollo / 44497
• FlyBaseID: FBgn0029114
• Length: 1346
• Species: Drosophila melanogaster
• Alignment Length: 528
• Identity: 132/528 - (25%)
• Similarity: 204/528 - (38%)
• Gaps: 142/528 - (26%)

  Fly    10 ASVSALGRPDLEDYCNDSYCHLLGR------SRTFSDKKATKLTEFHMDSCEKKVLKLMPNLRTL 68
            |.:|||||....:...:|...|..|      |....|..|.:||     |...::......|:.:
  Fly   228 AMLSALGRLTHLNMAKNSMSFLADRAFEGLLSLRVVDLSANRLT-----SLPPELFAETKQLQEI 287

  Fly    69 ELENCDSPDFTMNDLN--------QLPYLTSLQLRRGNLLGLHDEHFSKWPN------MKILM-- 117
            .|.|        |.:|        :|..|..|.|....|       .|:|.|      :|.||
  Fly   288 YLRN--------NSINVLAPGIFGELAELLVLDLASNEL-------NSQWINAATFVGLKRLMML 337

  Fly   118 -LGGNNITRLSNECFKGLAQLWLLSLPGNGIQGLPWDVFQNLPELLHLDLSGNRIETLHENIFTG 181
             |..|.|:||....|:.||.|.:|.|..|.|..||..:|.:|..|..|.||.|||..:.:....|
  Fly   338 DLSANKISRLEAHIFRPLASLQILKLEDNYIDQLPGGIFADLTNLHTLILSRNRISVIEQRTLQG 402

  Fly   182 VPKLEMLLLNGNPLTWIAPTSLKSLSNLRLLDMSNCGPLPDLSLPG----------AHTLIL--- 233
            :..|.:|.|:.|           .:|.:....:.||..|.||.|..          ||..:|
  Fly   403 LKNLLVLSLDFN-----------RISRMDQRSLVNCSQLQDLHLNDNKLQAVPEALAHVQLLKTL 456

  Fly   234 ----------DNSGVQRLDILGSVHKLQARKNHITEIK--LPDKSSVIE-LDLHSNLLTATDIPK 285
                      :|:.:.:|:   |::.|:..:|.:|.|:  :.|:.|.:: |:|..|.|.:.:...
  Fly   457 DVGENMISQIENTSITQLE---SLYGLRMTENSLTHIRRGVFDRMSSLQILNLSQNKLKSIEAGS 518

  Fly   286 LLTGMWRLQRLDLSEN----IIGIYAAAGSDNTSELFILPNLMYMNLSANRLTRLHFDSPIP--- 343
            |.... :||.:.|..|    |.|::..           ||||:::|:|.|||.:..: |.||
  Fly   519 LQRNS-QLQAIRLDGNQLKSIAGLFTE-----------LPNLVWLNISGNRLEKFDY-SHIPIGL 570

  Fly   344 -W-----ERLTHL---------------DASYNRIYAPAKVGIDEAFNLQSLHLEGNYINNFELT 387
             |     .|:|.|               |||||.:.......|..  :::.|:|..|.|:..:..
  Fly   571 QWLDVRANRITQLGNYFEIESELSLSTFDASYNLLTEITASSIPN--SVEVLYLNDNQISKIQPY 633

  Fly   388 PWKPHPSLKEVALYDNK---FQPKGY--------KNITKFFNEIGVNVLE---KTQYSQSNNTTP 438
            .:...|:|..|.|..|:   .:|...        :.|.:|:  ||.|..|   ...:.|..|...
  Fly   634 TFFKKPNLTRVDLVRNRLTTLEPNALRLSPIAEDREIPEFY--IGHNAYECDCNLDWLQKVNRES 696

  Fly   439 TCKPCIPD 446
            ..:|.:.|
  Fly   697 RTQPQLMD 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7800	NP_649770.1	leucine-rich repeat	46..64	CDD:275380	3/17 (18%)
		leucine-rich repeat	65..85	CDD:275380	5/27 (19%)
		LRR	68..482	CDD:443914	116/464 (25%)
		leucine-rich repeat	89..112	CDD:275380	6/22 (27%)
		leucine-rich repeat	113..136	CDD:275380	10/25 (40%)
		leucine-rich repeat	137..160	CDD:275380	9/22 (41%)
		leucine-rich repeat	161..184	CDD:275380	8/22 (36%)
		leucine-rich repeat	185..208	CDD:275380	4/22 (18%)
		leucine-rich repeat	209..246	CDD:275380	11/59 (19%)
		leucine-rich repeat	247..267	CDD:275380	5/21 (24%)
		leucine-rich repeat	268..292	CDD:275380	5/24 (21%)
		leucine-rich repeat	293..322	CDD:275380	7/32 (22%)
		leucine-rich repeat	395..406	CDD:275378	4/13 (31%)
Tollo	NP_524757.1	LRR	54..400	CDD:443914	55/191 (29%)
		leucine-rich repeat	100..123	CDD:275380
		leucine-rich repeat	124..144	CDD:275380
		leucine-rich repeat	154..177	CDD:275380
		leucine-rich repeat	178..201	CDD:275380
		leucine-rich repeat	212..235	CDD:275380	4/6 (67%)
		leucine-rich repeat	236..259	CDD:275380	3/22 (14%)
		LRR	239..634	CDD:443914	110/443 (25%)
		leucine-rich repeat	260..283	CDD:275380	5/27 (19%)
		leucine-rich repeat	284..307	CDD:275380	6/30 (20%)
		leucine-rich repeat	308..333	CDD:275380	7/31 (23%)
		leucine-rich repeat	334..357	CDD:275380	9/22 (41%)
		leucine-rich repeat	358..381	CDD:275380	9/22 (41%)
		leucine-rich repeat	382..405	CDD:275380	8/22 (36%)
		leucine-rich repeat	406..429	CDD:275380	7/33 (21%)
		leucine-rich repeat	430..452	CDD:275380	6/21 (29%)
		leucine-rich repeat	453..500	CDD:275380	9/49 (18%)
		leucine-rich repeat	501..521	CDD:275380	5/19 (26%)
		leucine-rich repeat	525..547	CDD:275380	7/32 (22%)
		leucine-rich repeat	548..573	CDD:275380	9/25 (36%)
		leucine-rich repeat	604..640	CDD:275380	5/37 (14%)
		LRR_8	616..>660	CDD:404697	10/43 (23%)
		leucine-rich repeat	641..688	CDD:275380	11/48 (23%)
		leucine-rich repeat	689..816	CDD:275380	4/16 (25%)
		LRR	<794..>920	CDD:443914
		leucine-rich repeat	817..864	CDD:275380
		leucine-rich repeat	865..888	CDD:275380
		leucine-rich repeat	889..910	CDD:275380
		TIR	1076..1211	CDD:214587