DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7800 and Tl

DIOPT Version :9

Sequence 1:NP_649770.1 Gene:CG7800 / 40963 FlyBaseID:FBgn0037552 Length:533 Species:Drosophila melanogaster
Sequence 2:NP_001262995.1 Gene:Tl / 43222 FlyBaseID:FBgn0262473 Length:1117 Species:Drosophila melanogaster


Alignment Length:669 Identity:140/669 - (20%)
Similarity:237/669 - (35%) Gaps:205/669 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 SDKKATKLTEFHMDSCE----------------KKVLKLMPNLRTLE---------------LEN 72
            ||.....:|..|:|...                ..:|..|.||..||               |||
  Fly   134 SDNLGMNITRQHLDRLHGLKRFRFTTRRLTHIPANLLTDMRNLSHLELRANIEEMPSHLFDDLEN 198

  Fly    73 CDSPDFTMNDLNQLPYLTSLQLRRGNLLGLHDEHFSKWPNMKILMLGGNNITRLSNECFKGLAQL 137
            .:|.:|..|.|.|:|        ||        .|.|.|.:|.|.|..|.:..|:...|:|...:
  Fly   199 LESIEFGSNKLRQMP--------RG--------IFGKMPKLKQLNLWSNQLHNLTKHDFEGATSV 247

  Fly   138 WLLSLPGNGIQGLPWDVFQNLPELLHLDLSGN--------------------------RIETLHE 176
            ..:.:..|||:.||.|||.:|..:..::||.|                          .:.||..
  Fly   248 LGIDIHDNGIEQLPHDVFAHLTNVTDINLSANLFRSLPQGLFDHNKHLNEVRLMNNRVPLATLPS 312

  Fly   177 NIFTGVPKLEMLLLNG-----------------------NPLTWIAPTSLKSLSNLRLLDMSN-- 216
            .:|...|:|::|.|..                       |.|..:..|.|:...||..||:||  
  Fly   313 RLFANQPELQILRLRAELQSLPGDLFEHSTQITNISLGDNLLKTLPATLLEHQVNLLSLDLSNNR 377

  Fly   217 CGPLPDLSLPGAHTLIL------DN--SGVQRLDI---LGSVHKLQARKNHITEIKLPDKSSVI- 269
            ...|||...  |||..|      ||  :|:.. ||   ||::..|...:|.:..|   |..:.: 
  Fly   378 LTHLPDSLF--AHTTNLTDLRLEDNLLTGISG-DIFSNLGNLVTLVMSRNRLRTI---DSRAFVS 436

  Fly   270 ------------ELDLHSNLL-----TATDIP-----KLLT-----------------GMWRLQR 295
                        ::||...||     |..:.|     .|||                 .|.:|:.
  Fly   437 TNGLRHLHLDHNDIDLQQPLLDIMLQTQINSPFGYMHGLLTLNLRNNSIIFVYNDWKNTMLQLRE 501

  Fly   296 LDLSENIIGIYAAAGSDNTSELFILPNLMYMNLSANRLTRLHFDSPIPW-----ERLTHLDASYN 355
            ||||.|.|   ::.|.::.:  |:..|.:::|::.|::.|:.....:..     ..|.|:|.:.|
  Fly   502 LDLSYNNI---SSLGYEDLA--FLSQNRLHVNMTHNKIRRIALPEDVHLGEGYNNNLVHVDLNDN 561

  Fly   356 RIYAPAKV--------GI-----DEAFNLQSLHLEGNYINNFELTPWK---PHPSLKEVALYDNK 404
            .:.....:        |:     ...|.|::..|..:..|..|.||.:   |...:..:...|:.
  Fly   562 PLVCDCTILWFIQLVRGVHKPQYSRQFKLRTDRLVCSQPNVLEGTPVRQIEPQTLICPLDFSDDP 626

  Fly   405 FQ---PKGYK-NITKFFNEIGVNV-----------------LEKTQYSQSNNTTPTCKPCIPDAR 448
            .:   |:|.. ::..:...:.:|.                 ::..:....|||............
  Fly   627 RERKCPRGCNCHVRTYDKALVINCHSGNLTHVPRLPNLHKNMQLMELHLENNTLLRLPSANTPGY 691

  Fly   449 DFPTSISADTNQTIDTKVNPL-SNDTYQWNVWNVLMLVSLIVSLFVNSFLIVKLIRLRGRNQFTQ 512
            :..||:....|......|:.| :|.|:....||.|.:::..|..|:|..:..:.::|.|......
  Fly   692 ESVTSLHLAGNNLTSIDVDQLPTNLTHLDISWNHLQMLNATVLGFLNRTMKWRSVKLSGNPWMCD 756

  Fly   513 SSSVPAIIEMFSNESDDEI 531
            .::.|.:  :|:.::.:.|
  Fly   757 CTAKPLL--LFTQDNFERI 773

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7800NP_649770.1 leucine-rich repeat 46..64 CDD:275380 5/33 (15%)
leucine-rich repeat 65..85 CDD:275380 10/34 (29%)
LRR_8 87..147 CDD:290566 14/59 (24%)
leucine-rich repeat 89..112 CDD:275380 4/22 (18%)
leucine-rich repeat 113..136 CDD:275380 7/22 (32%)
LRR_RI <131..334 CDD:238064 71/304 (23%)
leucine-rich repeat 137..160 CDD:275380 9/22 (41%)
LRR_8 140..195 CDD:290566 20/103 (19%)
leucine-rich repeat 161..184 CDD:275380 6/48 (13%)
leucine-rich repeat 185..208 CDD:275380 7/45 (16%)
leucine-rich repeat 209..246 CDD:275380 18/49 (37%)
leucine-rich repeat 247..267 CDD:275380 4/19 (21%)
leucine-rich repeat 268..292 CDD:275380 10/63 (16%)
leucine-rich repeat 293..322 CDD:275380 9/28 (32%)
leucine-rich repeat 395..406 CDD:275378 1/10 (10%)
TlNP_001262995.1 LRR_8 174..233 CDD:290566 22/74 (30%)
leucine-rich repeat 176..198 CDD:275380 4/21 (19%)
leucine-rich repeat 199..222 CDD:275380 10/38 (26%)
LRR_RI 216..542 CDD:238064 80/336 (24%)
LRR_8 221..281 CDD:290566 20/59 (34%)
leucine-rich repeat 223..270 CDD:275380 16/46 (35%)
leucine-rich repeat 271..294 CDD:275380 3/22 (14%)
leucine-rich repeat 295..320 CDD:275380 3/24 (13%)
leucine-rich repeat 321..343 CDD:275380 3/21 (14%)
LRR_8 342..402 CDD:290566 19/61 (31%)
leucine-rich repeat 344..367 CDD:275380 4/22 (18%)
leucine-rich repeat 368..391 CDD:275380 11/24 (46%)
LRR_8 390..450 CDD:290566 12/63 (19%)
leucine-rich repeat 392..415 CDD:275380 7/23 (30%)
leucine-rich repeat 416..439 CDD:275380 4/25 (16%)
leucine-rich repeat 440..474 CDD:275380 6/33 (18%)
leucine-rich repeat 475..498 CDD:275380 4/22 (18%)
LRR_8 477..534 CDD:290566 14/61 (23%)
leucine-rich repeat 499..520 CDD:275380 8/25 (32%)
leucine-rich repeat 523..552 CDD:275380 4/28 (14%)
LRRCT 561..619 CDD:214507 10/57 (18%)
LRRNT 631..667 CDD:214470 3/35 (9%)
leucine-rich repeat 664..693 CDD:275380 3/28 (11%)
LRR_8 669..726 CDD:290566 12/56 (21%)
leucine-rich repeat 694..715 CDD:275380 5/20 (25%)
leucine-rich repeat 716..737 CDD:275380 5/20 (25%)
LRRCT 751..800 CDD:214507 3/25 (12%)
TIR 858..996 CDD:214587
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453820
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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