Protein Alignment CG7800 and tlr22

DIOPT Version :10

• Sequence 1: NP_649770.1
• Gene: CG7800 / 40963
• FlyBaseID: FBgn0037552
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001122147.2
• Gene: tlr22 / 403135
• ZFINID: ZDB-GENE-040220-5
• Length: 955
• Species: Danio rerio
• Alignment Length: 589
• Identity: 130/589 - (22%)
• Similarity: 207/589 - (35%)
• Gaps: 177/589 - (30%)

  Fly    59 LKLMPNLR----TLELENCDSPDFTMNDLNQLPYLTSLQLRRGNLLGLHDEHFSKWPNMKILMLG 119
            ::|..|:|    :|.|..|.            |.|..|:|....:..|.:..|.....:..|.||
Zfish   293 IRLNGNVRLNKTSLLLSVCS------------PMLRVLRLIATKIKHLTNHMFDPCSELSELDLG 345

  Fly   120 GNNITRLSNECFKGLAQLWLLSLPGNGIQGLPWDVFQNLPELLHLDLSGNRIETLHENIFTGVPK 184
            ||.|:.||...|:|..||..|.|..|.:..:. :.||.|..|..:|||.|.|..|..|.|..:.:
Zfish   346 GNEISNLSQSMFRGFKQLKKLQLQINKLTRVT-NSFQILTSLEFIDLSRNHIHKLSCNDFANLTQ 409

  Fly   185 LEMLLLNGNPLTWIAPTSLKSLSNLRLL-----------DMSNCGP---------LPDLSLPGAH 229
            ::.|.|..|.::.|.....|.|.:|.:|           |:.:.||         ...|||..:|
Zfish   410 VKTLYLYSNKISSIRSCLFKDLKSLEVLRLGTNNLLKIDDVFSNGPYFLKELQLSYNKLSLIKSH 474

  Fly   230 TLILDNSGVQRLDILGSVHKLQARKNHITEIK---LPDKSSVIELDLHSNLLTA---TDIPKLLT 288
            |          ...|..::.|....|.|:||:   .....::..|.|.||.:|.   |..|.:.:
Zfish   475 T----------FGNLPQLNNLSLEDNQISEIEGYAFGGLENLTSLFLSSNKITGKTLTTHPNVFS 529

  Fly   289 GMWRLQRLDLSENII---------------------GIYAA----------------------AG 310
            ||..||.|||..|.|                     .:|:.                      .|
Zfish   530 GMPNLQNLDLFANSISFAYDKLKYPLFKDLKNLRELSLYSQRRGIGQLPSNLLEGLSSLQMFYIG 594

  Fly   311 SDNTSEL-----FILPNLMYMNLSANRLTRLHFDSPIPWE------RLTHLDASYNRIYAPAKVG 364
            :.|.::|     ...|.|.:::||.|.|..   |..||.|      .||.|..|..::
Zfish   595 NTNLNQLNPNLFNFTPQLWFLDLSKNALRE---DDAIPPELFHPIPNLTKLIISRTQL------- 649

  Fly   365 IDEAFN---------LQSLHLEGNYINNFELTPWKPHPSLKEVALYDNKFQPKGYKNITKFFNEI 420
              .:.|         |.:|...||.|::...|..|..|.|..:.|.:|.|             ..
Zfish   650 --RSLNFLLGANLNKLSTLRASGNEIDSVNETLIKSLPRLAVLDLQNNTF-------------TC 699

  Fly   421 GVNVLEKTQYSQSNNTTP-------TCKPCIPDARDFPTSISADTNQTIDTKVNPLSNDTYQWN- 477
            ..|......:::.|.:|.       ||        .:|.::...:....:|     .:.|:.|:
Zfish   700 DCNNAFFIDWAKKNESTQVYYLSRYTC--------SYPRTLRGTSLAEFNT-----DSCTFNWDY 751

  Fly   478 ----VWNVLMLVSLIVSLFVN---------SFLIVKLIRLRGRNQFTQSSSVPAIIEMFSNESDD 529
                ..::|::::|::|...|         .:|.:..:....|||..|:....|.|..  |..|:
Zfish   752 ICFVCSSILVILTLLLSFIWNFLRYQVVYTYYLFLAFLYDSRRNQSGQTFQYDAFISY--NTLDE 814

  Fly   530 EIIL 533
            ..::
Zfish   815 AWVM 818

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7800	NP_649770.1	leucine-rich repeat	46..64	CDD:275380	1/4 (25%)
		leucine-rich repeat	65..85	CDD:275380	4/23 (17%)
		LRR	68..482	CDD:443914	114/514 (22%)
		leucine-rich repeat	89..112	CDD:275380	5/22 (23%)
		leucine-rich repeat	113..136	CDD:275380	10/22 (45%)
		leucine-rich repeat	137..160	CDD:275380	7/22 (32%)
		leucine-rich repeat	161..184	CDD:275380	9/22 (41%)
		leucine-rich repeat	185..208	CDD:275380	6/22 (27%)
		leucine-rich repeat	209..246	CDD:275380	11/56 (20%)
		leucine-rich repeat	247..267	CDD:275380	5/22 (23%)
		leucine-rich repeat	268..292	CDD:275380	9/26 (35%)
		leucine-rich repeat	293..322	CDD:275380	11/76 (14%)
		leucine-rich repeat	395..406	CDD:275378	3/10 (30%)
tlr22	NP_001122147.2	LRR	<70..>242	CDD:443914
		leucine-rich repeat	71..91	CDD:275380
		leucine-rich repeat	92..115	CDD:275380
		leucine-rich repeat	116..139	CDD:275380
		leucine-rich repeat	140..163	CDD:275380
		leucine-rich repeat	164..213	CDD:275380
		leucine-rich repeat	214..338	CDD:275380	12/56 (21%)
		LRR	283..698	CDD:443914	108/452 (24%)
		leucine-rich repeat	339..362	CDD:275380	10/22 (45%)
		leucine-rich repeat	363..385	CDD:275380	7/22 (32%)
		leucine-rich repeat	386..409	CDD:275380	9/22 (41%)
		leucine-rich repeat	410..433	CDD:275380	6/22 (27%)
		leucine-rich repeat	434..457	CDD:275380	5/22 (23%)
		leucine-rich repeat	458..481	CDD:275380	6/32 (19%)
		leucine-rich repeat	482..505	CDD:275380	5/22 (23%)
		leucine-rich repeat	506..533	CDD:275380	9/26 (35%)
		leucine-rich repeat	534..561	CDD:275380	7/26 (27%)
		leucine-rich repeat	562..587	CDD:275380	1/24 (4%)
		leucine-rich repeat	588..606	CDD:275380	3/17 (18%)
		leucine-rich repeat	612..638	CDD:275380	9/28 (32%)
		leucine-rich repeat	639..662	CDD:275380	5/31 (16%)
		leucine-rich repeat	663..686	CDD:275380	7/22 (32%)
		PCC	669..>737	CDD:188093	16/88 (18%)
		leucine-rich repeat	687..705	CDD:275380	5/30 (17%)
		TIR	802..945	CDD:214587	4/19 (21%)