DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7800 and CG32055

DIOPT Version :9

Sequence 1:	NP_649770.1	Gene:	CG7800 / 40963	FlyBaseID:	FBgn0037552	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_729599.1	Gene:	CG32055 / 39188	FlyBaseID:	FBgn0052055	Length:	534	Species:	Drosophila melanogaster

Alignment Length:	341	Identity:	84/341 - (24%)
Similarity:	134/341 - (39%)	Gaps:	72/341 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 NLRTLELENCDSPDFTMNDLNQLPYLTSLQLRRGNLLGLHDEHFSKWPNMKILMLGGNNITRLSN 128
            |||.|.:.|.:..||....|..||.|..|.|....|..|....|...||:::|.:..||:..:..
  Fly   192 NLRFLSISNNNLRDFQWCHLRVLPKLEELHLHSNWLEHLDMGIFYALPNLRVLNVSNNNLFEIKR 256

  Fly   129 ECFKG---LAQLWLLSLPGNGIQGLPWDVFQNLPELLHLDLSGNRIETLHENIFTGVPKLEMLLL 190
            ..|..   :|.|.||....|.::.|...||..|.:|..|:|..|:|..:|...|.|:..|:.|.|
  Fly   257 TLFMAPGEIAPLELLDYSSNIVKVLDDSVFCRLKKLRTLNLWLNQINRIHPRAFLGLSSLQTLHL 321

  Fly   191 NGNPLTWIAPTSLKSLSNLRLLDMSNCGPLPDLSLPGAHTLILDNSGVQRLD-------ILGSVH 248
            .||.::.:......:|:.|..||:|                   .:.:|:|.       ||..:.
  Fly   322 QGNKISILPDDVFANLTALEKLDLS-------------------KNNIQKLGLRVFGERILRKLI 367

  Fly   249 KLQARKNHITE---IKLPDKSSVIELDLHSNLLTATDIPKLLTGMWRLQRLDLSENIIGIYAAAG 310
            .|....|:|.:   :.|.....:.||.|..|.|.:.|: ::...:.:||.|.::|
  Fly   368 YLDLSNNYIADLHPLALSSMPFIKELRLRRNRLVSLDL-RMFAPLRQLQLLTINE---------- 421

  Fly   311 SDNTSELFILPNLMYMNLSANRLTRLHFDSPIPWERLTHLDASYNRI-YAPAKVGIDEAFNLQSL 374
                                |||..:..:.....:||.||:.:.||: :.|..........|:::
  Fly   422 --------------------NRLEEIDGEILDTLDRLNHLELNNNRLTFLPDLKSSQNLLQLRNI 466

  Fly   375 HLEGNYINNFELTPWK 390
            .||||        ||:
  Fly   467 TLEGN--------PWQ 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7800	NP_649770.1	leucine-rich repeat	46..64	CDD:275380	84/341 (25%)
		leucine-rich repeat	65..85	CDD:275380	7/19 (37%)
		LRR_8	87..147	CDD:290566	18/62 (29%)
		leucine-rich repeat	89..112	CDD:275380	6/22 (27%)
		leucine-rich repeat	113..136	CDD:275380	4/25 (16%)
		LRR_RI	<131..334	CDD:238064	48/215 (22%)
		leucine-rich repeat	137..160	CDD:275380	8/22 (36%)
		LRR_8	140..195	CDD:290566	19/54 (35%)
		leucine-rich repeat	161..184	CDD:275380	8/22 (36%)
		leucine-rich repeat	185..208	CDD:275380	6/22 (27%)
		leucine-rich repeat	209..246	CDD:275380	8/43 (19%)
		leucine-rich repeat	247..267	CDD:275380	4/22 (18%)
		leucine-rich repeat	268..292	CDD:275380	6/23 (26%)
		leucine-rich repeat	293..322	CDD:275380	4/28 (14%)
		leucine-rich repeat	395..406	CDD:275378
CG32055	NP_729599.1	leucine-rich repeat	76..99	CDD:275380
		leucine-rich repeat	100..123	CDD:275380
		LRR_8	128..180	CDD:290566
		leucine-rich repeat	128..147	CDD:275380
		leucine-rich repeat	148..171	CDD:275380
		leucine-rich repeat	172..192	CDD:275380	84/341 (25%)
		LRR_RI	<187..400	CDD:238064	61/226 (27%)
		LRR_8	192..251	CDD:290566	20/58 (34%)
		leucine-rich repeat	193..216	CDD:275380	8/22 (36%)
		leucine-rich repeat	217..240	CDD:275380	6/22 (27%)
		leucine-rich repeat	241..267	CDD:275380	4/25 (16%)
		leucine-rich repeat	268..291	CDD:275380	8/22 (36%)
		LRR_8	290..350	CDD:290566	18/78 (23%)
		leucine-rich repeat	292..315	CDD:275380	8/22 (36%)
		leucine-rich repeat	316..339	CDD:275380	6/22 (27%)
		LRR_8	340..400	CDD:290566	16/78 (21%)
		leucine-rich repeat	340..365	CDD:275380	8/43 (19%)
		leucine-rich repeat	366..389	CDD:275380	4/22 (18%)
		leucine-rich repeat	390..413	CDD:275380	6/23 (26%)
		LRR_8	391..448	CDD:290566	18/87 (21%)
		leucine-rich repeat	414..437	CDD:275380	7/52 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453607
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930