DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7800 and rdo

DIOPT Version :9

Sequence 1:	NP_649770.1	Gene:	CG7800 / 40963	FlyBaseID:	FBgn0037552	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001286024.1	Gene:	rdo / 35077	FlyBaseID:	FBgn0243486	Length:	757	Species:	Drosophila melanogaster

Alignment Length:	463	Identity:	108/463 - (23%)
Similarity:	180/463 - (38%)	Gaps:	104/463 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 LNQLPYLTSLQLRRGNLLGLHDEHFSKWPNMKILMLGGNNITRLSNECFKGLAQLWLLSLPGNGI 147
            |.|...|..|::...||..:..|.|.....::||.|..||||.::...|:|...|..|.|..|.:
  Fly    78 LRQFMKLEILRITDSNLPAIGAESFWGLKYLRILDLSKNNITNITENNFRGQDNLLELDLSKNKV 142

  Fly   148 QGLPWDVFQNLPELLHLDLSGNRIETLHENIFTGVPKLEMLLLNGNPLTWIAPTSLKSLSNLRLL 212
            ..:....|::|.:|..|:|:.|.|..|.:..|..:.:|:.|.|:||||..:.|...:.:..|::|
  Fly   143 LRMASSTFRHLTDLRRLNLADNSIVELVQRNFFMLSRLKYLDLSGNPLQDLQPDVFRDVPELKVL 207

  Fly   213 DMSNCGPLPDLSLPGAHTLILDNSGVQRLDILGSVHKLQARKNHITEIKLPDKSSVIELD-LHSN 276
            ...||.              |.....|..::|..:.:|...:|   |.|..||....::. |...
  Fly   208 KCRNCQ--------------LKKINPQMYNLLPLLSELDLGRN---EFKFLDKDEFRDVKRLTKV 255

  Fly   277 LLTATDIPKLLTGMWRLQRLDLSENIIGIYAAAGSDNTSELFILPNLMYMNLSANRLTRLHFDSP 341
            ||....:..::..::|:|:                          :|.:::||.|||.::..||.
  Fly   256 LLDGNQLSVVVDQLFRMQK--------------------------SLNHLDLSYNRLAKVPNDSF 294

  Fly   342 IPWERLTHLDASYNRIYAPAKVGIDEAFNLQSLHLEGNYINN--------------FELTPWKPH 392
            :....||.||.|||::.......|....||.:|::.||.:.:              |.||..|..
  Fly   295 LQLTNLTFLDLSYNKLVRLEPQSIRSLSNLLTLNISGNVLMDLREMRETFEPLIYYFFLTCSKLF 359

  Fly   393 ----PSLKEVALYDNKFQPKG----YKNITKFFNEIGVNVLEKTQYSQSNNTTPTCKPC-----I 444
                |.|..:|:.|....|.|    :|.: ::.|..|        .|.:|.......||     :
  Fly   360 FQLIPQLTHLAIADMGTMPVGLLHPFKQL-RYLNISG--------NSLNNTALEVIDPCRELEFL 415

  Fly   445 PDARDFPTSISADT--------NQTIDTKVNPLSND--------------TYQWNVWNVLMLVSL 487
            ..:|:....||.||        |..:|.  |||..|              .::|:.:.:..|...
  Fly   416 DLSRNQLHGISEDTVLRIQGIRNVRLDN--NPLICDECHMGKLINVVRQLQWKWDTYPICFLPKS 478

  Fly   488 IVSLFVNS 495
            :....:|:
  Fly   479 LRGAEINN 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7800	NP_649770.1	leucine-rich repeat	46..64	CDD:275380
		leucine-rich repeat	65..85	CDD:275380	1/1 (100%)
		LRR_8	87..147	CDD:290566	19/59 (32%)
		leucine-rich repeat	89..112	CDD:275380	6/22 (27%)
		leucine-rich repeat	113..136	CDD:275380	9/22 (41%)
		LRR_RI	<131..334	CDD:238064	46/203 (23%)
		leucine-rich repeat	137..160	CDD:275380	6/22 (27%)
		LRR_8	140..195	CDD:290566	17/54 (31%)
		leucine-rich repeat	161..184	CDD:275380	7/22 (32%)
		leucine-rich repeat	185..208	CDD:275380	8/22 (36%)
		leucine-rich repeat	209..246	CDD:275380	7/36 (19%)
		leucine-rich repeat	247..267	CDD:275380	6/19 (32%)
		leucine-rich repeat	268..292	CDD:275380	3/24 (13%)
		leucine-rich repeat	293..322	CDD:275380	1/28 (4%)
		leucine-rich repeat	395..406	CDD:275378	3/10 (30%)
rdo	NP_001286024.1	leucine-rich repeat	84..107	CDD:275380	6/22 (27%)
		leucine-rich repeat	108..131	CDD:275380	9/22 (41%)
		LRR_8	131..190	CDD:290566	18/58 (31%)
		leucine-rich repeat	132..155	CDD:275380	6/22 (27%)
		LRR_RI	151..422	CDD:238064	73/322 (23%)
		leucine-rich repeat	156..179	CDD:275380	7/22 (32%)
		LRR_8	178..262	CDD:290566	24/100 (24%)
		leucine-rich repeat	180..203	CDD:275380	8/22 (36%)
		leucine-rich repeat	204..251	CDD:275380	13/63 (21%)
		leucine-rich repeat	252..275	CDD:275380	5/48 (10%)
		LRR_8	274..334	CDD:290566	21/85 (25%)
		leucine-rich repeat	276..299	CDD:275380	8/22 (36%)
		LRR_4	298..342	CDD:289563	13/43 (30%)
		leucine-rich repeat	300..323	CDD:275380	8/22 (36%)
		leucine-rich repeat	388..411	CDD:275380	6/31 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453825
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840