DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7800 and CG5096

DIOPT Version :9

Sequence 1:	NP_649770.1	Gene:	CG7800 / 40963	FlyBaseID:	FBgn0037552	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_723576.1	Gene:	CG5096 / 34410	FlyBaseID:	FBgn0032235	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	562	Identity:	118/562 - (20%)
Similarity:	176/562 - (31%)	Gaps:	231/562 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 DKKATKLTEFHMDS----CEKKVLKLMPN------------LRTLELENCDSPDFTMNDLNQLPY 88
            |.|..|....::|:    |.:|:...:..            .:|:.||:        |:|..:|.
  Fly    43 DSKLCKKCNCYIDTNLLDCSEKLQDWLSAEDWEDLTNGNVVFKTINLEH--------NNLTSVPI 99

  Fly    89 LTSLQLRRGNLLGLHDEHFSKWPNMKILMLGGNNITRLSNECFKGLAQLWLLSLPGNGIQGL--- 150
            |....:..                   |.|..|.|..:|...|:.|.:|..|.|..|.:...
  Fly   100 LPKYDVEN-------------------LYLANNQIDSISVGAFQNLTELVTLDLSHNRLTSKVLV 145

  Fly   151 ------PWDV--FQNLPELLHLDLSGNRIETLHENIFTGVPKLEMLLLNGNP---LTWIAPTSLK 204
                  |:.|  |::|..|..|:|..|.:.:|..::|..:|.:|.|:|..|.   :..::.|::.
  Fly   146 PDVFKGPFTVQDFESLENLKTLNLGYNDLHSLDADLFEHIPHIEELVLCSNSFHVIDQLSETAIS 210

  Fly   205 SLSNLRLLDMS--NCGPLPDLSLPGAHTLILDNSGVQRLDILGSVHKLQARKNHITEIKLPDKSS 267
            .|.:|::||:|  ....|||..|.|...|                           ||.:
  Fly   211 GLQSLKILDVSYMEIDDLPDTILHGPRDL---------------------------EIFI----- 243

  Fly   268 VIELDLHSNLLTATDIPKLLTGMWRLQRLDLS----ENIIGIYAAAGSDNTSELFILPNLMYMNL 328
                 ...||.  ..:||.|.....|..|.|:    ||:||       ||     :.|
  Fly   244 -----AAGNLF--NQLPKALKYATNLTSLVLNENPIENLIG-------DN-----VFP------- 282

  Fly   329 SANRLTRLHFDSPIPWERLTHLDASY-NRIYAPAKVGIDEAFNLQSL------------------ 374
                          |..:||||..:: :::|   |:|......||||
  Fly   283 --------------PLTKLTHLSMTFMSKLY---KIGPGAFSELQSLTELILSDNKLLNEIDEEA 330

  Fly   375 --------------HLEGNYINNFE--------LTPWKPHPSLKEVALYDNKFQPKGYKNITKFF 417
                          .||..|:||..        |..|....:|      |.:|.|........|.
  Fly   331 LSKNVTGGQYLDYPPLEKVYLNNCNVSTLPKELLVRWDKLKAL------DLRFNPWNCDESNDFL 389

  Fly   418 NEIGVNVLEKTQYSQSNNTTPTCKPCIPDARDF----PTSISADTNQTIDTKVNPLSNDTYQWNV 478
                :|||    ..:.|.|||..      |:|.    |..:                ||.....|
  Fly   390 ----INVL----IDRINKTTPVL------AKDVKCGGPNKL----------------NDVTLLRV 424

  Fly   479 WNVLMLVSLIVSLFVNSFLIVKLIRLRGRNQFTQSSSVPAII 520
            .|..|:.|...||.....|:|.||            :||.||
  Fly   425 ANEHMIESSTGSLIWVGLLVVLLI------------AVPTII 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7800	NP_649770.1	leucine-rich repeat	46..64	CDD:275380	3/21 (14%)
		leucine-rich repeat	65..85	CDD:275380	5/19 (26%)
		LRR_8	87..147	CDD:290566	13/59 (22%)
		leucine-rich repeat	89..112	CDD:275380	1/22 (5%)
		leucine-rich repeat	113..136	CDD:275380	7/22 (32%)
		LRR_RI	<131..334	CDD:238064	50/222 (23%)
		leucine-rich repeat	137..160	CDD:275380	8/33 (24%)
		LRR_8	140..195	CDD:290566	18/68 (26%)
		leucine-rich repeat	161..184	CDD:275380	6/22 (27%)
		leucine-rich repeat	185..208	CDD:275380	6/25 (24%)
		leucine-rich repeat	209..246	CDD:275380	10/38 (26%)
		leucine-rich repeat	247..267	CDD:275380	2/19 (11%)
		leucine-rich repeat	268..292	CDD:275380	5/23 (22%)
		leucine-rich repeat	293..322	CDD:275380	9/32 (28%)
		leucine-rich repeat	395..406	CDD:275378	2/10 (20%)
CG5096	NP_723576.1	LRR_RI	69..378	CDD:238064	83/416 (20%)
		leucine-rich repeat	85..104	CDD:275380	7/26 (27%)
		LRR_8	105..174	CDD:290566	19/87 (22%)
		leucine-rich repeat	105..128	CDD:275380	7/41 (17%)
		leucine-rich repeat	129..163	CDD:275380	8/33 (24%)
		LRR_8	163..222	CDD:290566	16/58 (28%)
		leucine-rich repeat	164..187	CDD:275380	6/22 (27%)
		leucine-rich repeat	188..214	CDD:275380	6/25 (24%)
		leucine-rich repeat	215..238	CDD:275380	9/22 (41%)
		leucine-rich repeat	239..261	CDD:275380	8/60 (13%)
		LRR_8	260..322	CDD:290566	22/97 (23%)
		leucine-rich repeat	262..286	CDD:275380	11/56 (20%)
		leucine-rich repeat	287..311	CDD:275380	8/26 (31%)
		leucine-rich repeat	346..369	CDD:275380	7/22 (32%)
		leucine-rich repeat	370..388	CDD:275380	4/23 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45617
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100