DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7800 and Nrros

DIOPT Version :9

Sequence 1:NP_649770.1 Gene:CG7800 / 40963 FlyBaseID:FBgn0037552 Length:533 Species:Drosophila melanogaster
Sequence 2:NP_001334110.1 Gene:Nrros / 224109 MGIID:2445095 Length:693 Species:Mus musculus


Alignment Length:471 Identity:110/471 - (23%)
Similarity:173/471 - (36%) Gaps:154/471 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 LKLMPNLRTLELENCDSPDFTMNDLNQLPYLTSLQLRRGNLLGLHDEHFSKWP-------NMKIL 116
            |:..|.|..|.|.:|.....:.....:..:|.:|.|....|    .|::.:..       .::.|
Mouse    77 LQAYPRLENLSLHSCHLDRISHYAFREQGHLRNLVLADNRL----SENYKESAAALHTLLGLRRL 137

  Fly   117 MLGGNNITR-LSNECFKGLAQLWLLSLPGNGIQGLPWDVFQNLPELLHLDLSGNRIETLHENIFT 180
            .|.||::|. ::....:.|:.|.::||..|.:..|...:|:.|..|:.|||..|.|..:....|.
Mouse   138 DLSGNSLTEDMAALMLQNLSSLEVVSLARNTLMRLDDSIFEGLEHLVELDLQRNYIFEIEGGAFD 202

  Fly   181 GVPKLEMLLLNGNPLTWIAPTSLKSLS---------------------NLRLLDMSN-------- 216
            |:.:|..|.|..|.|..|...||..|.                     .|.:||:|:        
Mouse   203 GLTELRRLNLAYNNLPCIVDFSLTQLRFLNVSYNILEWFLAAREEVAFELEILDLSHNQLLFFPL 267

  Fly   217 ---CGPLPDLSLPGAHTLIL--DNSGVQR---------------LDILGSVHKL----------- 250
               ||.|        |||:|  :|.|..|               |.:.|:|..:           
Mouse   268 LPQCGKL--------HTLLLQDNNMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVNLWEEFSS 324

  Fly   251 ------------QARKNHITEIKLPDKSSVIELDLHSNLLTATDI-----PKLLTGMWRLQRLDL 298
                        |.:..|:.:..|....|:..|:|:.|.|....|     |..||      .|||
Mouse   325 SDLSALRFLDMSQNQFRHLPDGFLKKTPSLSHLNLNQNCLKMLHIREHEPPGALT------ELDL 383

  Fly   299 SEN-IIGIYAAAGSDNTSELFILPNLMYMNLSANRL----TRLHFDSPIPWERLTHLDASYNRI- 357
            |.| :..::.|.|...:     |.||...|||:|:|    |.| ||:.   ..:|.:|.|:|:| 
Mouse   384 SHNQLAELHLAPGLTGS-----LRNLRVFNLSSNQLLGVPTGL-FDNA---SSITTIDMSHNQIS 439

  Fly   358 YAPAKVGID-----------EAFNLQSLHLEG-----------------------NY-INNFELT 387
            ..|..|.:|           ...:|:||.|:|                       |: :.|..::
Mouse   440 LCPQMVPVDWEGPPSCVDFRNMGSLRSLSLDGCGLKALQDCPFQGTSLTHLDLSSNWGVLNGSIS 504

  Fly   388 P-WKPHPSLKEVALYD 402
            | |...|:|:.::|.|
Mouse   505 PLWAVAPTLQVLSLRD 520

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7800NP_649770.1 leucine-rich repeat 46..64 CDD:275380 1/4 (25%)
leucine-rich repeat 65..85 CDD:275380 4/19 (21%)
LRR_8 87..147 CDD:290566 15/67 (22%)
leucine-rich repeat 89..112 CDD:275380 5/29 (17%)
leucine-rich repeat 113..136 CDD:275380 6/23 (26%)
LRR_RI <131..334 CDD:238064 69/284 (24%)
leucine-rich repeat 137..160 CDD:275380 7/22 (32%)
LRR_8 140..195 CDD:290566 18/54 (33%)
leucine-rich repeat 161..184 CDD:275380 8/22 (36%)
leucine-rich repeat 185..208 CDD:275380 9/43 (21%)
leucine-rich repeat 209..246 CDD:275380 15/64 (23%)
leucine-rich repeat 247..267 CDD:275380 4/42 (10%)
leucine-rich repeat 268..292 CDD:275380 8/28 (29%)
leucine-rich repeat 293..322 CDD:275380 8/29 (28%)
leucine-rich repeat 395..406 CDD:275378 3/8 (38%)
NrrosNP_001334110.1 LRR 1. /evidence=ECO:0000255 58..79 1/1 (100%)
PLN00113 60..>439 CDD:215061 93/388 (24%)
leucine-rich repeat 60..82 CDD:275380 1/4 (25%)
LRR 2. /evidence=ECO:0000255 82..103 4/20 (20%)
leucine-rich repeat 83..106 CDD:275380 4/22 (18%)
LRR 3. /evidence=ECO:0000255 106..127 5/24 (21%)
leucine-rich repeat 107..133 CDD:275380 5/29 (17%)
LRR 4. /evidence=ECO:0000255 133..155 5/21 (24%)
leucine-rich repeat 134..158 CDD:275380 6/23 (26%)
LRR_8 157..217 CDD:404697 19/59 (32%)
LRR 5. /evidence=ECO:0000255 158..179 6/20 (30%)
leucine-rich repeat 159..182 CDD:275380 7/22 (32%)
LRR 6. /evidence=ECO:0000255 182..203 7/20 (35%)
leucine-rich repeat 183..206 CDD:275380 8/22 (36%)
LRR 7. /evidence=ECO:0000255 206..227 8/20 (40%)
leucine-rich repeat 207..251 CDD:275380 9/43 (21%)
LRR 8. /evidence=ECO:0000255 228..239 1/10 (10%)
leucine-rich repeat 230..249 CDD:275380 0/18 (0%)
LRR 9. /evidence=ECO:0000255 251..272 4/20 (20%)
leucine-rich repeat 252..273 CDD:275380 5/20 (25%)
LRR 10. /evidence=ECO:0000255 273..294 8/28 (29%)
leucine-rich repeat 274..329 CDD:275380 11/62 (18%)
PLN00113 309..>638 CDD:215061 53/227 (23%)
LRR 11. /evidence=ECO:0000255 329..350 3/20 (15%)
leucine-rich repeat 330..353 CDD:275380 3/22 (14%)
LRR 12. /evidence=ECO:0000255 353..374 6/20 (30%)
leucine-rich repeat 354..377 CDD:275380 6/22 (27%)
LRR 13. /evidence=ECO:0000255 377..398 9/26 (35%)
leucine-rich repeat 378..403 CDD:275380 10/35 (29%)
LRR 14. /evidence=ECO:0000255 403..424 10/21 (48%)
leucine-rich repeat 404..427 CDD:275380 10/26 (38%)
LRR 15. /evidence=ECO:0000255 427..448 7/20 (35%)
leucine-rich repeat 428..463 CDD:275380 8/34 (24%)
LRR 16. /evidence=ECO:0000255 463..484 5/20 (25%)
leucine-rich repeat 464..486 CDD:275380 5/21 (24%)
LRR 17. /evidence=ECO:0000255 486..507 3/20 (15%)
leucine-rich repeat 487..512 CDD:275380 4/24 (17%)
LRR 18. /evidence=ECO:0000255 512..533 3/9 (33%)
leucine-rich repeat 513..537 CDD:275380 3/8 (38%)
LRR 19. /evidence=ECO:0000255 537..558
leucine-rich repeat 538..559 CDD:275380
LRR 20. /evidence=ECO:0000255 559..580
LRR 21. /evidence=ECO:0000255 585..605
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45617
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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