DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7800 and lron-1

DIOPT Version :9

Sequence 1:NP_649770.1 Gene:CG7800 / 40963 FlyBaseID:FBgn0037552 Length:533 Species:Drosophila melanogaster
Sequence 2:NP_510424.4 Gene:lron-1 / 181553 WormBaseID:WBGene00008093 Length:607 Species:Caenorhabditis elegans


Alignment Length:537 Identity:124/537 - (23%)
Similarity:198/537 - (36%) Gaps:134/537 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 NCD---SPDFTMNDLNQLP------------------------YLTSLQLRRGNLLGLHDEHF-- 107
            |||   |.|..:..|:..|                        .:..|.||...|...|...|  
 Worm    40 NCDGGSSLDAVLESLSNSPQAIDSLTISNTPIEKMPGYAFQGFQIKKLFLRNNGLRSFHPNTFTG 104

  Fly   108 SKWPNMKILMLGGNNITRLSNECFKGLAQLWLLSLPGNGIQGLPWDVF---QNLPELLHLDLSGN 169
            :...:::.|.:.||.|..:.......|.||.:||||.|.|:.:..:.|   .:...||.||||.|
 Worm   105 NLENSLEELEIRGNYIDGIPQSGVSILKQLKILSLPDNLIEYVQDNAFLSYHSRDSLLKLDLSAN 169

  Fly   170 RIETLHENIFTGVPKLEMLLLNGNPLTWIAPTSLKSLSNLRLLDMS---------NCGPLPDL-- 223
            .:..:|.....|:..|..|.|:.|.|:.|...:|:::.:|..|.:.         |..|||:|  
 Worm   170 NLTAIHPTGLLGLENLSQLSLDKNLLSEIPSQALENIPSLEDLSLGVNRIHTISRNSLPLPNLKS 234

  Fly   224 -----------------SLPGAHTLILDNSGVQRLDI-----LGSVHKLQARKN-HITEIKLPDK 265
                             ..|....|.|.|:.:..:|.     :|.:..|....| .||.|:...|
 Worm   235 LSLEVNQIRLIPSDSFSETPLLSYLYLGNNLLTSIDASMFLHIGGLKVLSMSNNKDITSIQANGK 299

  Fly   266 SSVIELDLHSNLLTATDIPKLLTGMWRLQRLDLSENIIGIYAAAGSDNTSELFILPNLMYMNLSA 330
            .||.:..|...:|.....|.|:    ||:..|.|.:.|         ....|..:.::..:.||.
 Worm   300 LSVQQFKLCICILAFQHAPSLI----RLELFDCSISRI---------EPKSLQKVQHIQVILLSR 351

  Fly   331 NRLTRLHFDSPIPWERLTHLDASYNRIYAPAKVGIDEAFNLQSLHLEGNYINNFELTPWKPHPSL 395
            |::||:..|:......|:.||.|.|.|.|.......:...|.||.|..|.:.           ||
 Worm   352 NQITRISHDTFSNLPELSELDLSGNSINAVDDFAFSQLPMLTSLDLSSNRLE-----------SL 405

  Fly   396 KEVALYDNKFQPKGYKNITKFFNEIGV---------NVLEKTQYSQSNNTTPTCKPCIPDARDF- 450
            ....:||:..|    |..:....::.:         :::...::.:.|....|.....|.|:.: 
 Worm   406 PSNVIYDSLMQ----KKTSPVQRKLSIQNNPWRCDKDLMWLRKWLRDNGDVTTAASNSPPAKCWT 466

  Fly   451 PTSISA-DTNQTIDTKV------NPL------------SNDTYQWNVWNV------LMLVSLIVS 490
            |:::|. |..|| |:|:      .|:            ||.|.|....|.      |.||.||:.
 Worm   467 PSNLSGLDLRQT-DSKLPHKTTKPPVDQFQYKNQQVTNSNGTSQLGYQNPHTEVNGLALVGLILG 530

  Fly   491 L----FVNSFLIVKLIR 503
            :    ||:..::..|:|
 Worm   531 IVLVVFVSCIILGYLMR 547

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7800NP_649770.1 leucine-rich repeat 46..64 CDD:275380
leucine-rich repeat 65..85 CDD:275380 6/15 (40%)
LRR_8 87..147 CDD:290566 19/85 (22%)
leucine-rich repeat 89..112 CDD:275380 6/24 (25%)
leucine-rich repeat 113..136 CDD:275380 5/22 (23%)
LRR_RI <131..334 CDD:238064 60/239 (25%)
leucine-rich repeat 137..160 CDD:275380 8/25 (32%)
LRR_8 140..195 CDD:290566 20/57 (35%)
leucine-rich repeat 161..184 CDD:275380 9/22 (41%)
leucine-rich repeat 185..208 CDD:275380 7/22 (32%)
leucine-rich repeat 209..246 CDD:275380 12/69 (17%)
leucine-rich repeat 247..267 CDD:275380 6/20 (30%)
leucine-rich repeat 268..292 CDD:275380 5/23 (22%)
leucine-rich repeat 293..322 CDD:275380 5/28 (18%)
leucine-rich repeat 395..406 CDD:275378 3/10 (30%)
lron-1NP_510424.4 PRK15370 <58..>289 CDD:185268 51/230 (22%)
leucine-rich repeat 85..109 CDD:275380 6/23 (26%)
leucine-rich repeat 110..133 CDD:275380 5/22 (23%)
leucine-rich repeat 134..157 CDD:275380 8/22 (36%)
leucine-rich repeat 161..184 CDD:275380 9/22 (41%)
leucine-rich repeat 185..208 CDD:275380 7/22 (32%)
leucine-rich repeat 209..231 CDD:275380 5/21 (24%)
leucine-rich repeat 232..255 CDD:275380 1/22 (5%)
leucine-rich repeat 256..279 CDD:275380 4/22 (18%)
leucine-rich repeat 280..319 CDD:275380 10/38 (26%)
leucine-rich repeat 320..343 CDD:275380 7/35 (20%)
LRR_8 343..402 CDD:338972 18/58 (31%)
leucine-rich repeat 344..367 CDD:275380 6/22 (27%)
leucine-rich repeat 368..391 CDD:275380 7/22 (32%)
leucine-rich repeat 392..410 CDD:275380 7/28 (25%)
leucine-rich repeat 414..435 CDD:275378 2/24 (8%)
LRRCT 431..>472 CDD:214507 5/40 (13%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45617
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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