Protein Alignment CG7800 and LRG1

DIOPT Version :9

• Sequence 1: NP_649770.1
• Gene: CG7800 / 40963
• FlyBaseID: FBgn0037552
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_443204.1
• Gene: LRG1 / 116844
• HGNCID: 29480
• Length: 347
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 59/198 - (29%)
• Similarity: 79/198 - (39%)
• Gaps: 43/198 - (21%)

  Fly    43 ATKLTEFHMDSCEKKVLKLMPNLRTLELENCDSPDFTMNDLNQLPYLTSLQLRRGNLLGLHDEHF 107
            |:||.|.|:.|         ..|.:|      ||:|    |..:|.|..|.|.|..|.||....|
Human    91 ASKLQELHLSS---------NGLESL------SPEF----LRPVPQLRVLDLTRNALTGLPPGLF 136

  Fly   108 SKWPNMKILMLGGNNITRLSNECFKGLAQLWLLSLPGNGIQGLPWDVFQNLPELLHLDLSGNRIE 172
            .....:..|:|..|.:..|......||..|..|.|.||.::.||..:..|...|..|||..|::|
Human   137 QASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLE 201

  Fly   173 TLHENIFTG------------------------VPKLEMLLLNGNPLTWIAPTSLKSLSNLRLLD 213
            ||..::..|                        .|.|..|.||||.|..:|..:.:.|..|.:||
Human   202 TLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLD 266

  Fly   214 MSN 216
            :||
Human   267 LSN 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7800	NP_649770.1	leucine-rich repeat	46..64	CDD:275380	4/17 (24%)
		leucine-rich repeat	65..85	CDD:275380	6/19 (32%)
		LRR_8	87..147	CDD:290566	20/59 (34%)
		leucine-rich repeat	89..112	CDD:275380	8/22 (36%)
		leucine-rich repeat	113..136	CDD:275380	6/22 (27%)
		LRR_RI	<131..334	CDD:238064	34/110 (31%)
		leucine-rich repeat	137..160	CDD:275380	8/22 (36%)
		LRR_8	140..195	CDD:290566	23/78 (29%)
		leucine-rich repeat	161..184	CDD:275380	9/46 (20%)
		leucine-rich repeat	185..208	CDD:275380	9/22 (41%)
		leucine-rich repeat	209..246	CDD:275380	5/8 (63%)
		leucine-rich repeat	247..267	CDD:275380
		leucine-rich repeat	268..292	CDD:275380
		leucine-rich repeat	293..322	CDD:275380
		leucine-rich repeat	395..406	CDD:275378
LRG1	NP_443204.1	LRR_8	79..128	CDD:290566	17/55 (31%)
		LRR_RI	<82..248	CDD:238064	51/175 (29%)
		LRR 1	93..114		11/39 (28%)
		leucine-rich repeat	94..117	CDD:275380	10/41 (24%)
		LRR_8	116..176	CDD:290566	20/59 (34%)
		LRR 2	117..138		8/20 (40%)
		leucine-rich repeat	118..141	CDD:275380	8/22 (36%)
		LRR 3	141..162		4/20 (20%)
		leucine-rich repeat	142..165	CDD:275380	6/22 (27%)
		LRR 4	165..186		7/20 (35%)
		leucine-rich repeat	166..189	CDD:275380	8/22 (36%)
		LRR_8	169..224	CDD:290566	16/54 (30%)
		LRR 5	189..210		8/20 (40%)
		leucine-rich repeat	190..213	CDD:275380	9/22 (41%)
		LRR_8	213..272	CDD:290566	15/57 (26%)
		LRR 6	213..234		0/20 (0%)
		leucine-rich repeat	214..237	CDD:275380	0/22 (0%)
		LRR 7	237..258		8/20 (40%)
		leucine-rich repeat	238..261	CDD:275380	9/22 (41%)
		LRR 8	261..282		5/9 (56%)
		leucine-rich repeat	262..285	CDD:275380	5/8 (63%)
		LRRCT	299..346	CDD:214507

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45617
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100