DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7800 and lrrc32.2

DIOPT Version :9

Sequence 1:	NP_649770.1	Gene:	CG7800 / 40963	FlyBaseID:	FBgn0037552	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_031747547.1	Gene:	lrrc32.2 / 100496842	XenbaseID:	XB-GENE-6461207	Length:	682	Species:	Xenopus tropicalis

Alignment Length:	512	Identity:	115/512 - (22%)
Similarity:	175/512 - (34%)	Gaps:	169/512 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 EFHMDSCEKKVLKLMPNL----RTLELENCDSPDFTMNDLNQLPYLTSL--------QLRRGNLL 100
            |..:..|...:..:..||    :||:|.:......|::.::.|..|.||        ::.||..|
Frog    23 ESEVHCCGLNIFDIPENLPRSIKTLDLSHNLITKITVSPISHLHSLQSLSLGYNQLEEIDRGAFL 87

  Fly   101 GL-------------------HDEHFSKWPNMKILMLGGNNI-TRLSNECFKGLAQLWLLSLPGN 145
            .:                   ||..|:..||:|||.|..|:: :::......|...|..|.|.||
Frog    88 AVTQLDTLNLAANQLHKHYQRHDGVFASLPNLKILSLAQNHLDSKMVTFYLNGSRSLKKLDLSGN 152

  Fly   146 GIQGLPWDVFQNLPELLHLDLSGNRIETLHENIFTGVPKLEMLLLNGNPLTWIAPTSLKSLSNLR 210
            .:..|....|.....|..|||:.|.|..:.|..|..:..|..|.|.||.:..||...|..|..|.
Frog   153 KMVTLSPGTFDGALHLTELDLANNDITGITEGTFDALQNLRTLNLAGNFIQCIASFDLTQLQVLN 217

  Fly   211 LLD------MSNCGPLP-DLSLPGAHTLILDNSGVQRLDILGSVHKLQ---ARKNHITEIKLPDK 265
            |..      .||....| .||     ||.|..:.::|...|.::||:|   ...|::.|: .|..
Frog   218 LSSNALRFFYSNDSQTPYQLS-----TLDLSQNNLKRFPFLPNIHKIQYLNLSGNNLVEM-APGS 276

  Fly   266 SSVIE--------------------------------LDLHSNLLTATDIPK-LLTGMWRLQRLD 297
            .:.:|                                |||..|.||:  .|. .|:...||:.|:
Frog   277 ETTLENVESSHWFEAAEGLDLFSAIEYSNYNLSHLRDLDLSHNHLTS--FPSHFLSNATRLENLN 339

  Fly   298 LSENIIGIYAAAGSDNTSE-------------------------------LF-ILPNLMYMNLSA 330
            |:.|.|.......|...|.                               || .|||:.::||..
Frog   340 LAHNCITYMREEPSSTVSSQVKDWTHIPVTLNALKVLNLEGNSIQTVPQWLFKFLPNIQHLNLKG 404

  Fly   331 NRLTRLHFDSP-----------------IPWERLTHLDASYNRI---------YAPAKV------ 363
            |.:.......|                 .|  :|.:|:..:|.|         :.|..|
Frog   405 NNVILRPQSHPKMINGSSKDDICTNFSRAP--KLKYLNLGHNYITQLPPRAFHHTPLAVLDLSEN 467

  Fly   364 -----------GIDEAFNLQSLHLEGNYINNFELTPWKPHPSLKEVA---LYDNKFQ 406
                       |::|  :||.|.|:||.:|..:    ...|.||.:.   :.:||.:
Frog   468 LGLTLEESTMEGLEE--SLQFLSLQGNQMNESQ----AKLPCLKSLQFLNMSNNKLR 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7800	NP_649770.1	leucine-rich repeat	46..64	CDD:275380	2/15 (13%)
		leucine-rich repeat	65..85	CDD:275380	5/23 (22%)
		LRR_8	87..147	CDD:290566	22/87 (25%)
		leucine-rich repeat	89..112	CDD:275380	9/49 (18%)
		leucine-rich repeat	113..136	CDD:275380	6/23 (26%)
		LRR_RI	<131..334	CDD:238064	68/277 (25%)
		leucine-rich repeat	137..160	CDD:275380	7/22 (32%)
		LRR_8	140..195	CDD:290566	19/54 (35%)
		leucine-rich repeat	161..184	CDD:275380	8/22 (36%)
		leucine-rich repeat	185..208	CDD:275380	9/22 (41%)
		leucine-rich repeat	209..246	CDD:275380	12/43 (28%)
		leucine-rich repeat	247..267	CDD:275380	6/22 (27%)
		leucine-rich repeat	268..292	CDD:275380	9/56 (16%)
		leucine-rich repeat	293..322	CDD:275380	10/60 (17%)
		leucine-rich repeat	395..406	CDD:275378	4/13 (31%)
lrrc32.2	XP_031747547.1	leucine-rich repeat	25..43	CDD:275380	3/17 (18%)
		PLN00113	36..>497	CDD:215061	108/472 (23%)
		leucine-rich repeat	45..67	CDD:275380	5/21 (24%)
		leucine-rich repeat	68..91	CDD:275380	6/22 (27%)
		leucine-rich repeat	92..118	CDD:275380	3/25 (12%)
		leucine-rich repeat	119..143	CDD:275380	6/23 (26%)
		leucine-rich repeat	144..167	CDD:275380	7/22 (32%)
		leucine-rich repeat	168..191	CDD:275380	8/22 (36%)
		leucine-rich repeat	192..212	CDD:275380	8/19 (42%)
		leucine-rich repeat	213..236	CDD:275380	6/22 (27%)
		leucine-rich repeat	237..258	CDD:275380	7/25 (28%)
		leucine-rich repeat	259..280	CDD:275380	4/21 (19%)
		leucine-rich repeat	335..372	CDD:275380	7/36 (19%)
		leucine-rich repeat	373..396	CDD:275380	3/22 (14%)
		leucine-rich repeat	436..456	CDD:275380	4/19 (21%)
		leucine-rich repeat	459..483	CDD:275380	3/25 (12%)
		leucine-rich repeat	484..506	CDD:275380	9/25 (36%)
		leucine-rich repeat	507..528	CDD:275380	2/12 (17%)
		leucine-rich repeat	529..553	CDD:275380
		leucine-rich repeat	554..573	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45617
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100