Protein Alignment grn and gata6

DIOPT Version :10

• Sequence 1: NP_001262366.1
• Gene: grn / 40962
• FlyBaseID: FBgn0001138
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_571632.2
• Gene: gata6 / 58076
• ZFINID: ZDB-GENE-000622-1
• Length: 501
• Species: Danio rerio
• Alignment Length: 617
• Identity: 170/617 - (27%)
• Similarity: 220/617 - (35%)
• Gaps: 242/617 - (39%)

  Fly    27 GGGNGGGVSPQTNGLGSAGSSLAHSH------HSLSSGASSAGSSVGVGSALG---------GGG 76
            |..:...|..:.:...|.||....|:      ..|.|.|.:....||...|.|         |..
Zfish     4 GDNSWSMVKREVSSSSSPGSPAEQSYLNTDRRDRLRSPAPTHLDPVGSRRAEGRPLHSYVHFGHP 68

  Fly    77 GSGLDTS-DMSAFYALE-------SNGHHRRYYPSYHQHTSRMPSTHASPQVCRPHFHTPLSPWL 133
            .:.|.:| |::.|..|:       |.||.|              .||....:..|
Zfish    69 NNALPSSDDVTLFTDLDQGNKLIISGGHPR--------------ETHKGGLIVDP---------- 109

  Fly   134 TSEHKSFAPASAWSMGQFACPQEPQVEHKLGQMGQSHQTTAAGQHSFPFPPT-----------PP 187
            |..:::.|.|:|.|                 |.|.:...:|...||.|..|.           |.
Zfish   110 TDMYQTLAIAAAQS-----------------QAGYNDTPSAGYMHSNPTSPVYVPTSRVGTMIPN 157

  Fly   188 KDSTPDSVQTGPSEYQAVMNAFMHQQATGSTSLTDASCALDIKPSIQNGSASGSSGSGTTHTS-- 250
            ....|..|.|.||            .|..|.|:..           |....|.|..:|:.|||
Zfish   158 LSYLPPGVSTQPS------------HAVSSHSVWS-----------QPAPESPSYSTGSPHTSNR 199

  Fly   251 -----TPKQREGTASTTNSSSNSSSSQQQQQQQQQQQQQQQQSSSNTTASSNTSASSSAAAASLS 310
                 :|....||:..|:.::..:.:.:.|.                                ||
Zfish   200 FHYSPSPPMNNGTSRDTSYTTPLNVNSRDQY--------------------------------LS 232

  Fly   311 AAVAASAATSSNGLFDGTAQAYSSGGSGGGGGGGSGSGGYDTSSYASYHHAAAHHQAAAVAAANM 375
            ..:                                 ||.| .|.|..| ......|..|...|..
Zfish   233 RPI---------------------------------SGSY-PSPYPPY-VTPQLSQLPAAWPAGP 262

  Fly   376 FQSSSVAAAAVRHSMAAAQAHHHHHHHHSGHHHSGSSSGLHGLGGSVGGTAGMGSMSGNSGGAGS 440
            |::|.:      ||:.:..|                ...:.|..|.:     :..|
Zfish   263 FENSML------HSLQSRSA----------------PLAIRGPNGDL-----LEEM--------- 291

  Fly   441 LSGHSGAGSNAGSNCLDVKPVRTKPRTSAEGRECVNCGATSTPLWRRDGTGHYLCNACGLYYKMN 505
                                        .|.|||||||:.||||||||||||:||||||||.|||
Zfish   292 ----------------------------VESRECVNCGSMSTPLWRRDGTGHFLCNACGLYSKMN 328

  Fly   506 GQNRPLIKPKRRLTLQSLQSAAKRAGTSCANCKTTTTTLWRRNASGEPVCNACGLYYKLHNVNRP 570
            |.:||||||::|:      |:::|.|.|||||:|:|||||||||.|||||||||||.|||.|.||
Zfish   329 GLSRPLIKPQKRM------SSSRRIGLSCANCQTSTTTLWRRNAEGEPVCNACGLYTKLHGVPRP 387

  Fly   571 LTMKKEGIQTRNRKLSSKSKKKKGLGGGCLPI 602
            |.|||||||||.||..|.||.|...|...:|:
Zfish   388 LAMKKEGIQTRKRKPKSLSKVKGSSGSSSVPM 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grn	NP_001262366.1	ZnF_GATA	473..517	CDD:238123	36/43 (84%)
		ZnF_GATA	533..583	CDD:238123	42/49 (86%)
gata6	NP_571632.2	GATA-N	112..285	CDD:461628	49/301 (16%)
		ZnF_GATA	296..340	CDD:238123	36/43 (84%)
		ZnF_GATA	350..401	CDD:238123	42/50 (84%)