Protein Alignment grn and gata4

DIOPT Version :10

• Sequence 1: NP_001262366.1
• Gene: grn / 40962
• FlyBaseID: FBgn0001138
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_001016949.1
• Gene: gata4 / 549703
• XenbaseID: XB-GENE-487458
• Length: 394
• Species: Xenopus tropicalis
• Alignment Length: 534
• Identity: 171/534 - (32%)
• Similarity: 212/534 - (39%)
• Gaps: 179/534 - (33%)

  Fly   198 GPSEYQAVMNAFMHQQATGSTS-----LTDASCALDIKPSIQNGSASGSSGSGTTHTSTPKQREG 257
            ||..|:.. ..:|| .||.:||     .|..|..:...|.:|   .||||..|
 Frog    12 GPPAYEGA-GGYMH-SATAATSPVYVPTTRVSSMIPSLPYLQ---TSGSSQQG------------ 59

  Fly   258 TASTTNSSSNSSSSQQQQQQQQQQQQQQQQSSSNTTASSNTSASSS---AAAASLSAAVAASAAT 319
                     :..|......|...:.......:|:...|...:.|||   :||::.....::..|.
 Frog    60 ---------SPVSGHNMWAQAGAEPSAYNPGTSHPPVSPRFTFSSSPPISAASNREVPYSSPLAI 115

  Fly   320 SSNGLFDGTAQAYSSGGSGGGGGGGSGSGGYDTSSYASYHHAAAHHQAAAVAAANMFQSSSVAAA 384
            |:||     .:.|           |...|    ::|:|.:.|.......|...|:.|.||.
 Frog   116 SANG-----REQY-----------GRALG----ATYSSPYPAYMSPDMGATWTASPFDSSM---- 156

  Fly   385 AVRHSMAAAQAHHHHHHHHSGHHHSGSSSGLHGLGGSVGGTAGMGSMSGNSGGAGSLSGHSGAGS 449
                                          ||.|....|..|               |.|
 Frog   157 ------------------------------LHNLQNRAGPAA---------------SRH----- 171

  Fly   450 NAGSNCLDVKPVRTKPRTS-----AEGRECVNCGATSTPLWRRDGTGHYLCNACGLYYKMNGQNR 509
                           |...     :||||||||||.|||||||||||||||||||||:||||.||
 Frog   172 ---------------PNIEFFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINR 221

  Fly   510 PLIKPKRRLTLQSLQSAAKRAGTSCANCKTTTTTLWRRNASGEPVCNACGLYYKLHNVNRPLTMK 574
            |||||:|||      ||::|.|.|||||.|||||||||||.|||||||||||.|||.|.|||.||
 Frog   222 PLIKPQRRL------SASRRVGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMK 280

  Fly   575 KEGIQTRNRKLSSKSKKKKGLGGGCLPIGGHLGMGDFKPLDPSKGFGGGFSASMAQHGH------ 633
            |||||||.||..:.||.|.           ..|......|.||       ::|....|.
 Frog   281 KEGIQTRKRKPKNLSKSKT-----------PTGQNSSDSLTPS-------TSSTNSAGEEMRPIK 327

  Fly   634 LSSGLHPAHAHMHGSWYTGGMGALGASSGLQGGFSTAGSLSGAVVPHS------QPYHLGLSSMG 692
            :..||.|.:.|         ..:|..:|.|    ||..|...:..|.|      |.:|..:::..
 Frog   328 IEPGLSPPYGH---------SSSLSQASVL----STTTSHGSSSYPMSSLKLSPQNHHSTINTSP 379

  Fly   693 TWRTDYTXWSGNNL 706
            ...:.:..|  |||
 Frog   380 QASSKHDSW--NNL 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grn	NP_001262366.1	ZnF_GATA	473..517	CDD:238123	39/43 (91%)
		ZnF_GATA	533..583	CDD:238123	43/49 (88%)
gata4	NP_001016949.1	GATA-N	1..174	CDD:461628	50/276 (18%)
		ZnF_GATA	185..235	CDD:238123	44/55 (80%)
		ZnF_GATA	239..290	CDD:238123	43/50 (86%)
		Peptidase_S64	293..>387	CDD:369740	23/124 (19%)