Protein Alignment grn and gata2b

DIOPT Version :10

• Sequence 1: NP_001262366.1
• Gene: grn / 40962
• FlyBaseID: FBgn0001138
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_001002689.2
• Gene: gata2b / 436962
• ZFINID: ZDB-GENE-040718-440
• Length: 428
• Species: Danio rerio
• Alignment Length: 643
• Identity: 196/643 - (30%)
• Similarity: 243/643 - (37%)
• Gaps: 279/643 - (43%)

  Fly    48 LAHSHHSLSSGAS-SAGSSVGVGSALGG---GGGSGLDTSDMSAFYA-LESNGHHRRYYPSYHQH 107
            :.|:|||...|.| |.....|:|....|   .|...|...::..|.: |:|.|:     |.||.|
Zfish    11 MMHAHHSAMMGTSDSVSPHAGLGHHSSGYMEPGAPLLQPDEVDVFLSHLDSQGN-----PYYHTH 70

  Fly   108 TSR----MPSTHA---SPQVCRPH-FHTPLSPWLTSEHKSFAPA---SAWSMGQFACPQEPQVEH 161
            .||    ...|||   ...:|||| .:|...|.|.:...:|:.|   .:|::....    ..|.|
Zfish    71 GSRARMSYSQTHARLTGGSMCRPHLINTHGLPLLDNSKSTFSTAQHHGSWTVSHLG----KAVLH 131

  Fly   162 KLGQMGQSHQTTAAG---------------QHS----FPFPPTPPKDSTPDSVQTGPSEYQAVMN 207
            ..|  .:|.....||               ||.    :..|||||||.:||..      ..||.:
Zfish   132 SAG--AESSNGLYAGTGAPASGPMPCLSMTQHCSAQLYCLPPTPPKDVSPDPA------CAAVRD 188

  Fly   208 A---FMHQQATGSTSLTDA---SCALDIKPSIQNGSASGSSGSGTTHTSTPKQREGTASTTNSSS 266
            |   .:|        |.|.   .|:..|:           |......|:||
Zfish   189 AGKYHLH--------LVDGMKMECSSPIR-----------SNPHLAQTTTP-------------- 220

  Fly   267 NSSSSQQQQQQQQQQQQQQQQSSSNTTASSNTSASSSAAAASLSAAVAASAATSSNGLFDGTAQA 331
                                                                             
Zfish   221 ----------------------------------------------------------------- 220

  Fly   332 YSSGGSGGGGGGGSGSGGYDTSSYASYHHAAAHHQAAAVAAANMFQSSSVAAAAVRHSMAAAQAH 396
                                ..||..|..|.||...|:|     |.|.::
Zfish   221 --------------------IPSYPDYSVAGAHEYPASV-----FHSRNL--------------- 245

  Fly   397 HHHHHHHSGHHHSGSSSGLHGLGGSVGGTAGMGSMSGNSGGAGSLSGHSGAGSNAGSNCLDVKPV 461
                                           :|:|:                    :.|
Zfish   246 -------------------------------LGNMT--------------------TKC------ 253

  Fly   462 RTKPRTSAEGRECVNCGATSTPLWRRDGTGHYLCNACGLYYKMNGQNRPLIKPKRRLTLQSLQSA 526
            ::|.| :..|||||||||||||||||||||||||||||||:||||||||||:|||||      ||
Zfish   254 KSKNR-AFSGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIRPKRRL------SA 311

  Fly   527 AKRAGTSCANCKTTTTTLWRRNASGEPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKLSSKSKK 591
            ::||||.||||:|.|||||||||:|||||||||||||||||||||||||:||||||||:|.||||
Zfish   312 SRRAGTCCANCQTGTTTLWRRNANGEPVCNACGLYYKLHNVNRPLTMKKDGIQTRNRKMSGKSKK 376

  Fly   592 KKGLGGGCLPIGGHLGMGDFKPLDPSKGFGGGFSASMAQHGHLSS-----GLHPAHAH 644
            ::         |.|....|....|....|     :.||...|..:     .||||.:|
Zfish   377 RR---------GEHFHQFDSCVHDKPSSF-----SHMANIHHPFNMTPQIQLHPAFSH 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grn	NP_001262366.1	ZnF_GATA	473..517	CDD:238123	41/43 (95%)
		ZnF_GATA	533..583	CDD:238123	44/49 (90%)
gata2b	NP_001002689.2	GAT1	205..>410	CDD:227928	132/412 (32%)
		ZnF_GATA	264..314	CDD:238123	46/55 (84%)
		ZnF_GATA	319..369	CDD:238123	45/49 (92%)