DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment grn and elt-1

DIOPT Version :9

Sequence 1:	NP_001262366.1	Gene:	grn / 40962	FlyBaseID:	FBgn0001138	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_001033435.1	Gene:	elt-1 / 177794	WormBaseID:	WBGene00001249	Length:	488	Species:	Caenorhabditis elegans

Alignment Length:	397	Identity:	131/397 - (32%)
Similarity:	189/397 - (47%)	Gaps:	76/397 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   275 QQQQQQQQQQQQQSSSNTTASSNTSASSSAAAASLSAAVAA-SAATSSNGLFDGTAQAYS----- 333
            |..:|:....:.:....|..:|:..||.:..:::.:|::|. |..||:...::.|..:|.
Worm    66 QPIEQENMDYEGKPVEFTLGTSSGGASLAPTSSTTAASIAPFSYNTSATNYYNTTPSSYPMFLNY 130

  Fly   334 --SGGSG--------GGGGGGSGSGGYDTSSYASYHHAAAHHQAAAVAAANMFQSSSVAAAAVRH 388
              :||:.        .|......:|.:.|.:..||.:....        .|.:...::|||....
Worm   131 QYAGGTTVTTDMDAFSGMDMSMNNGVFGTQNNPSYFYPTTQ--------LNTYGYDTLAAATTAS 187

  Fly   389 SMAAAQAHHHHHHHHSGHHHSGSS------------SGLHGLGGSV----------GGTAGMGSM 431
            .:..      :::..:.:...|:.            |.:..:..||          .|.||..:.
Worm   188 GITV------NNNQLNVNIVQGNGTIVPQPITQNIISTVSNVQSSVPINNSQPLTPTGLAGCSTS 246

  Fly   432 SGNSGGAGSLSGHSGAGSNAGSNCLDVKPVRTKPRTSAEGRECVNCGATSTPLWRRDGTGHYLCN 496
            ||:|..:.|.:..:....|..|............:.|.|.|||||||..:||||||||:|:||||
Worm   247 SGSSSASSSSANSTSTPKNTISKANRSSGGANNSQFSTEDRECVNCGVHNTPLWRRDGSGNYLCN 311

  Fly   497 ACGLYYKMNGQNRPLIKPKRRLTLQSLQSAAKRAGTSCANCKTTTTTLWRRNASGEPVCNACGLY 561
            |||||:|||...|||:|||:|     .|:|.||.|..|.||:|.||||||||..|.|||||||||
Worm   312 ACGLYFKMNHHARPLVKPKKR-----QQNAQKRTGIECVNCRTNTTTLWRRNGEGHPVCNACGLY 371

  Fly   562 YKLHNVNRPLTMKKEGIQTRNRKLSSKSKK--KKGLGGGCLPIG-----------------GHLG 607
            :|||.|.||:||||:||||||||||:|..:  ||..||....:|                 |..|
Worm   372 FKLHKVERPITMKKDGIQTRNRKLSAKGSRRMKKENGGTPTSMGMPTTSSSISSGIELDQSGVWG 436

  Fly   608 MGDFKPL 614
            |.:.:|:
Worm   437 MKNTQPM 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
grn	NP_001262366.1	ZnF_GATA	470..517	CDD:214648	35/46 (76%)
		ZnF_GATA	473..517	CDD:238123	33/43 (77%)
		ZnF_GATA	529..578	CDD:214648	34/48 (71%)
		ZnF_GATA	533..583	CDD:238123	37/49 (76%)
elt-1	NP_001033435.1	ZnF_GATA	285..332	CDD:214648	35/46 (76%)
		ZnF_GATA	288..339	CDD:238123	36/55 (65%)
		ZnF_GATA	339..388	CDD:214648	34/48 (71%)
		ZnF_GATA	343..394	CDD:238123	38/50 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	68	1.000	Domainoid score	I6377
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	1	1.000	-	-		otm14642
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10071
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1745
SonicParanoid	1	1.000	-	-		X385
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.040