Protein Alignment grn and Gata5

DIOPT Version :10

• Sequence 1: NP_001262366.1
• Gene: grn / 40962
• FlyBaseID: FBgn0001138
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_032119.2
• Gene: Gata5 / 14464
• MGIID: 109497
• Length: 404
• Species: Mus musculus
• Alignment Length: 442
• Identity: 146/442 - (33%)
• Similarity: 175/442 - (39%)
• Gaps: 184/442 - (41%)

  Fly   198 GPSEYQAVMNAFMHQQATGS---TSLTDASCALDIKPSIQNGSASGSSGSGTTHTSTPKQREGTA 259
            |...| |...||:|...|||   .:.|.....|...||.:.||
Mouse    12 GQGTY-ADSGAFLHSSGTGSPVFVAPTRMPSMLPYLPSCEPGS---------------------- 53

  Fly   260 STTNSSSNSSSSQQQQQQQQQQQQQQQQSSSNTTASSNTSASSSAAAASLSAAVAASAATSSNGL 324
                                                   .|.:.||.:|.:.||||.::...:|.
Mouse    54 ---------------------------------------QAPALAAHSSWTQAVAADSSAFGSGS 79

  Fly   325 FDGTAQ----------AYSSGGSGGGGGGGSGSGG-----------YDT-------SSYASYHHA 361
            ....|.          |:|..|||.||..|...||           |.|       :||.:.:.|
Mouse    80 PHPPAAHPPGATTFPFAHSPPGSGSGGSAGVRDGGAFQGALLAREQYPTPLGRPMGASYPTTYPA 144

  Fly   362 AAHHQAAAVAAANMFQSSSVAAAAVRHSMAAAQAHHHHHHHHSGHHHSGS--SSGLHGLGGSVGG 424
                          :.||.||.:..                      ||:  ||.||||....||
Mouse   145 --------------YMSSDVAPSWT----------------------SGAFDSSILHGLQARPGG 173

  Fly   425 TAGMGSMSGNSGGAGSLSGHSGAGSNAGSNCLDVKPVRTKPRTS----------AEGRECVNCGA 479
            ..|.                                     |||          .||||||||||
Mouse   174 LPGR-------------------------------------RTSFVPDFLEEFPGEGRECVNCGA 201

  Fly   480 TSTPLWRRDGTGHYLCNACGLYYKMNGQNRPLIKPKRRLTLQSLQSAAKRAGTSCANCKTTTTTL 544
            .|||||||||||||||||||||:||||.||||::|::||      |:::|:|..|:||.|.||||
Mouse   202 LSTPLWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRL------SSSRRSGLCCSNCHTATTTL 260

  Fly   545 WRRNASGEPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKLSSKSKKKKGLG 596
            ||||:.|||||||||||.|||.|.|||.||||.||||.||..:.:|.|...|
Mouse   261 WRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKNPAKIKGSSG 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
grn	NP_001262366.1	ZnF_GATA	473..517	CDD:238123	37/43 (86%)
		ZnF_GATA	533..583	CDD:238123	38/49 (78%)
Gata5	NP_032119.2	GATA-N	1..181	CDD:461628	57/303 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	71..112		10/40 (25%)
		ZnF_GATA	195..239	CDD:238123	37/43 (86%)
		ZnF_GATA	250..300	CDD:238123	38/49 (78%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	293..332		9/20 (45%)