DRSC/TRiP Functional Genomics Resources

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Protein Alignment grn and GATA5

DIOPT Version :9

Sequence 1:NP_001262366.1 Gene:grn / 40962 FlyBaseID:FBgn0001138 Length:712 Species:Drosophila melanogaster
Sequence 2:NP_536721.1 Gene:GATA5 / 140628 HGNCID:15802 Length:397 Species:Homo sapiens


Alignment Length:310 Identity:127/310 - (40%)
Similarity:151/310 - (48%) Gaps:77/310 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   293 TASSNTSA----SSSAAAASLSAAVAASAATSSNGLFDGTAQAYSSGGSGGGGGGGSGSGGYDTS 353
            ||::::||    |....||....|.|...|.|.:|           .||||..||..||      
Human    67 TATADSSAFGPGSPHPPAAHPPGATAFPFAHSPSG-----------PGSGGSAGGRDGS------ 114

  Fly   354 SYASYHHAAAHHQAAAVAAANMFQSSSVAAAAVRHSMAAAQAHHHHHHHHSGHHHSGSSSGLHGL 418
               :|..|....:..|........:|..|......|...||:                       
Human   115 ---AYQGALLPREQFAAPLGRPVGTSYSATYPAYVSPDVAQS----------------------- 153

  Fly   419 GGSVGGTAGM--GSMSGNSGGAGSLSGHSGAGSNAGSNCLDVKPVRTKPRTSAEGRECVNCGATS 481
                 .|||.  ||:         |.|..|......|:.|:..|        .||||||||||.|
Human   154 -----WTAGPFDGSV---------LHGLPGRRPTFVSDFLEEFP--------GEGRECVNCGALS 196

  Fly   482 TPLWRRDGTGHYLCNACGLYYKMNGQNRPLIKPKRRLTLQSLQSAAKRAGTSCANCKTTTTTLWR 546
            ||||||||||||||||||||:||||.||||::|::||      |:::|||..|.||.||.|||||
Human   197 TPLWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRL------SSSRRAGLCCTNCHTTNTTLWR 255

  Fly   547 RNASGEPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKLSSKSKKKKGLG 596
            ||:.|||||||||||.|||.|.|||.||||.||||.||..:.:|.:...|
Human   256 RNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKTIAKARGSSG 305

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
grnNP_001262366.1 ZnF_GATA 470..517 CDD:214648 40/46 (87%)
ZnF_GATA 473..517 CDD:238123 37/43 (86%)
ZnF_GATA 529..578 CDD:214648 37/48 (77%)
ZnF_GATA 533..583 CDD:238123 38/49 (78%)
GATA5NP_536721.1 GATA-N 1..170 CDD:283099 35/159 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 48..116 20/68 (29%)
ZnF_GATA 184..229 CDD:214648 39/44 (89%)
ZnF_GATA 188..232 CDD:238123 37/43 (86%)
ZnF_GATA <253..293 CDD:238123 31/39 (79%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 281..356 12/25 (48%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5641
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000130
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1745
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.840

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