Protein Alignment Arl8 and ARF1

DIOPT Version :10

• Sequence 1: NP_649769.1
• Gene: Arl8 / 40961
• FlyBaseID: FBgn0037551
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_001649.1
• Gene: ARF1 / 375
• HGNCID: 652
• Length: 181
• Species: Homo sapiens
• Alignment Length: 173
• Identity: 54/173 - (31%)
• Similarity: 97/173 - (56%)
• Gaps: 1/173 - (0%)

  Fly    12 FKSIFWKEEMELTLVGLQFSGKTTFVNVIASGQFAEDMIPTVGFNMRKITRGNVTIKVWDIGGQP 76
            ||.:|.|:||.:.:|||..:||||.:..:..|:.. ..|||:|||:..:...|::..|||:|||.
Human     9 FKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIV-TTIPTIGFNVETVEYKNISFTVWDVGGQD 72

  Fly    77 RFRSMWERYCRGVNAIVYMVDAADLDKLEASRNELHSLLDKPQLAGIPVLVLGNKRDLPGALDET 141
            :.|.:|..|.:....::::||:.|.:::..:|.||..:|.:.:|....:||..||:|||.|::..
Human    73 KIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAA 137

  Fly   142 GLIERMNLSSIQDREICCYSISCKEKDNIDITLQWLIQHSKSQ 184
            .:.:::.|.|::.|.....:......|.:...|.||....::|
Human   138 EITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arl8	NP_649769.1	Arl10_like	22..180	CDD:206724	47/157 (30%)
ARF1	NP_001649.1	Important for the stable binding to the membranes. /evidence=ECO:0000250|UniProtKB:P84080	3..16		3/6 (50%)
		ARF	5..179	CDD:128474	53/170 (31%)