DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9667 and Isy1

DIOPT Version :9

Sequence 1:	NP_649768.2	Gene:	CG9667 / 40960	FlyBaseID:	FBgn0037550	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001014210.1	Gene:	Isy1 / 362394	RGDID:	1307688	Length:	284	Species:	Rattus norvegicus

Alignment Length:	274	Identity:	171/274 - (62%)
Similarity:	210/274 - (76%)	Gaps:	7/274 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MARNAEKAMTTLARWRAAKEVESGEKERRPYLASECHDLPRCEKFRLEIIRDISKKVAQIQNAGL 65
            ||||||||||.|||:|.|:..|...|||||:|||||.:||:.||:|.:||.:|||||||||||||
  Rat     1 MARNAEKAMTALARFRQAQLEEGKVKERRPFLASECTELPKAEKWRRQIIGEISKKVAQIQNAGL 65

  Fly    66 GEFRIRDLNDEINKLLREKRHWENQISSLGGPHYRRYGPKMFDAEGREVPGNRGYKYFGAAKDLP 130
            |||||||||||||||||||.|||.:|..||||.|.:.||||.|.||:||||||||||||||||||
  Rat    66 GEFRIRDLNDEINKLLREKGHWEVRIKELGGPDYGKVGPKMLDHEGKEVPGNRGYKYFGAAKDLP 130

  Fly   131 GVRELFEQDPPPPPRKSRAELMKDIDAEYYGYRDDEDGVLIPLEERIERAAIQKAVQEWR-EKMA 194
            |||||||::|.|||||:||||||.||.|||||.|::|||::|||:..|:....:.|::|: |:.|
  Rat   131 GVRELFEKEPLPPPRKTRAELMKAIDFEYYGYLDEDDGVIVPLEQEYEKRLRAELVEKWKAEREA 195

  Fly   195 R--DGRIIDDEEEDEIYPLSGPAREAIEDAKARAAVEDPHGLLASKFTAHVPVPTQQDVQEALLR 257
            |  .|...::|||:||...:....|:.|:.....|.||..    .||.||||||:||:::|||:|
  Rat   196 RLARGEKEEEEEEEEINIYAVTEEESDEEGSQEKAGEDGQ----QKFIAHVPVPSQQEIEEALVR 256

  Fly   258 QRKRELLEKYAGGT 271
            ::|.|||:|||..|
  Rat   257 RKKMELLQKYASET 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9667	NP_649768.2	Isy1	1..266	CDD:283825	167/267 (63%)
Isy1	NP_001014210.1	Isy1	1..265	CDD:283825	167/267 (63%)
Isy1	NP_001014210.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	196..243		16/50 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353153
Domainoid	1	1.000	326	1.000	Domainoid score	I1158
eggNOG	1	0.900	-	-		E1_KOG3068
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6283
Inparanoid	1	1.050	331	1.000	Inparanoid score	I2362
OMA	1	1.010	-	-		QHG55550
OrthoDB	1	1.010	-	-		D1513531at2759
OrthoFinder	1	1.000	-	-		FOG0004185
OrthoInspector	1	1.000	-	-		oto96642
orthoMCL	1	0.900	-	-		OOG6_102669
Panther	1	1.100	-	-	LDO	PTHR13021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2932
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770