Protein Alignment CG7878 and PRP28

DIOPT Version :10

• Sequence 1: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_010529.3
• Gene: PRP28 / 851830
• SGDID: S000002651
• Length: 588
• Species: Saccharomyces cerevisiae
• Alignment Length: 579
• Identity: 168/579 - (29%)
• Similarity: 278/579 - (48%)
• Gaps: 96/579 - (16%)

  Fly   141 SNVIDAINHVRKQVTNSGDRGQDRDNRDHGSNERYDGGGYDRYKGNSYEFNPTSSES-------- 197
            |.:|..||  :|:..:....|:....|.....||   ...:|.|.|.....||.|:|
Yeast     8 SQLIAGIN--KKKGLDENTSGKISKPRFLNKQER---SKQERLKENEESLTPTQSDSAKVEIKKV 67

  Fly   198 ------------------NKDNGD------------LTG---IIDWEALNKASIAATAARWSKCP 229
                              :|.||.            |:|   |:...|::        ..|....
Yeast    68 NSRDDSFFNETNDKKRNPSKQNGSKFHFSWNESEDTLSGYDPIVSTRAID--------LLWKGKT 124

  Fly   230 PLTKNFYKEAPEVANLTKSEIERIREENNK-----ITVSYVFEPKEGETSPPIPNPVWTFEQCFA 289
            |      |.|.|.:.:.|...|:...|.|:     :...|....|.|    .:.||:..:|:...
Yeast   125 P------KNAAESSYMGKHWTEKSLHEMNERDWRILKEDYAIVTKGG----TVENPLRNWEELNI 179

  Fly   290 EYPDMLEE-ITKMGFSKPSPIQSQAWP---ILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQST 350
            ...|:|.. |.::.|..|:|||....|   .:.|..|.:|:|.||:||||||::|.:|... :|.
Yeast   180 IPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVASTGSGKTLAFVIPILIKMS-RSP 243

  Fly   351 PRGTR----GGANVLVLAPTRELALQIEMEVKKY-------SFRGMKAVCVYGGGNRNMQISDLE 404
            ||...    .|...|:|||||||..||:.|.:|.       |....|.:.:.||.:.......|.
Yeast   244 PRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIWSKESNYDCKVISIVGGHSLEEISFSLS 308

  Fly   405 RGAEIIICTPGRLNDLIMANVIDVSTITYLVLDEADRMLDMGFEPQIRKVM--LDIRPD----RQ 463
            .|.:|::.|||||.|.:..:::.:..:..|||||||:|:|:|||.|:..::  :||..|    ||
Yeast   309 EGCDILVATPGRLIDSLENHLLVMKQVETLVLDEADKMIDLGFEDQVTNILTKVDINADSAVNRQ 373

  Fly   464 TIMTSATWPPGVRRLAQSYMKNPIQVCVGSLDLAATHSVKQIIKLMEDDMDKFNTITSFVKNMSS 528
            |:|.:||..|.:.::|..||:.|:...:| ::..:...::|:::..::|.|||..:...|....
Yeast   374 TLMFTATMTPVIEKIAAGYMQKPVYATIG-VETGSEPLIQQVVEYADNDEDKFKKLKPIVAKYD- 436

  Fly   529 TDKIIIFCGRKVRADDLSSELTLDGFM-TQCIHGNRDQMDREQAIADIKSGVVRILVATDVASRG 592
             ..||||...|..||.|:.:...:..| ...:||::.|..||.::...::..|:|::||:||:||
Yeast   437 -PPIIIFINYKQTADWLAEKFQKETNMKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARG 500

  Fly   593 LDIEDITHVINYDFPHNIEEYVHRVGRTGRAGRQGTSISFFT-REDWAMAKELIEILQE 650
            |||.:::.|:|:.....:::|:||:||||||..:||::||.: .||.::.:||.:.:::
Yeast   501 LDIPNVSLVVNFQISKKMDDYIHRIGRTGRAANEGTAVSFVSAAEDESLIRELYKYVRK 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH_1	92..152	CDD:459630	4/10 (40%)
		DEAD-like_helicase_N	174..663	CDD:475120	160/546 (29%)
PRP28	NP_010529.3	SrmB	175..559	CDD:440279	131/387 (34%)