DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7878 and RH20

DIOPT Version :9

Sequence 1:	NP_649767.1	Gene:	CG7878 / 40959	FlyBaseID:	FBgn0037549	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_001322402.1	Gene:	RH20 / 841958	AraportID:	AT1G55150	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	515	Identity:	222/515 - (43%)
Similarity:	325/515 - (63%)	Gaps:	43/515 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 GGYDRYKGNSYEFNPTSSESNKDNGDLTGIIDWEALNKASIAATAARWSKCPPLTKNFYKEAPEV 242
            ||...|..:.   :.|||:.:.|..:....:|.:.|.               |..||||.|:|.|
plant    49 GGTSSYGSSG---SHTSSKKDNDGNESPRKLDLDGLT---------------PFEKNFYVESPAV 95

  Fly   243 ANLTKSEIERIREENNKITVSYVFEPKEGETSPPIPNPVWTFEQCFAEYPD-MLEEITKMGFSKP 306
            |.:|.:|:|..| :..:|||       ||:   .||.||.:|..  ..:|| :|||:.|.||::|
plant    96 AAMTDTEVEEYR-KLREITV-------EGK---DIPKPVKSFRD--VGFPDYVLEEVKKAGFTEP 147

  Fly   307 SPIQSQAWPILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQSTPRGTRG-GANVLVLAPTRELA 370
            :|||||.||:.::|.|:||||:||:||||::|||.::|...|  |....| |..|||||||||||
plant   148 TPIQSQGWPMAMKGRDLIGIAETGSGKTLSYLLPAIVHVNAQ--PMLAHGDGPIVLVLAPTRELA 210

  Fly   371 LQIEMEVKKY-SFRGMKAVCVYGGGNRNMQISDLERGAEIIICTPGRLNDLIMANVIDVSTITYL 434
            :||:.|..|: |...:|..|:|||..:..|:.||::|.||:|.|||||.|::.:|..::..:|||
plant   211 VQIQQEASKFGSSSKIKTTCIYGGVPKGPQVRDLQKGVEIVIATPGRLIDMMESNNTNLRRVTYL 275

  Fly   435 VLDEADRMLDMGFEPQIRKVMLDIRPDRQTIMTSATWPPGVRRLAQSYMKNPIQVCVGSLDLAAT 499
            |||||||||||||:|||||::..|||||||:..|||||..|.:|::.::.||.:|.:||.||.|.
plant   276 VLDEADRMLDMGFDPQIRKIVSHIRPDRQTLYWSATWPKEVEQLSKKFLYNPYKVIIGSSDLKAN 340

  Fly   500 HSVKQIIKLMEDDMDKFNTITSFVKNMSSTDKIIIFCGRKVRADDLSSELTLDGFMTQCIHGNRD 564
            .:::||:.::.:. .|:|.:...::::....:|::|...|...|.::.:|.:||:....|||::.
plant   341 RAIRQIVDVISES-QKYNKLVKLLEDIMDGSRILVFLDTKKGCDQITRQLRMDGWPALSIHGDKS 404

  Fly   565 QMDREQAIADIKSGVVRILVATDVASRGLDIEDITHVINYDFPHNIEEYVHRVGRTGRAGRQGTS 629
            |.:|:..:::.:||...|:.|||||:||||::|:.:|||||||.::|:||||:|||||||.:||:
plant   405 QAERDWVLSEFRSGKSPIMTATDVAARGLDVKDVKYVINYDFPGSLEDYVHRIGRTGRAGAKGTA 469

  Fly   630 ISFFTREDWAMAKELIEILQEAEQEVPDELHNMARRFKAMKDKRAAEG-GGFGGRGGRFG 688
            .:|||..:...||||..|||||.|:|..||.:|.|     .......| |||..||.|.|
plant   470 YTFFTVANARFAKELTNILQEAGQKVSPELASMGR-----STAPPPPGLGGFRDRGSRRG 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH-I	92..150	CDD:238053
		DEADc	288..489	CDD:238167	108/203 (53%)
		DEXDc	298..505	CDD:214692	109/208 (52%)
		Helicase_C	514..624	CDD:278689	44/109 (40%)
RH20	NP_001322402.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000439
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910