Protein Alignment CG7878 and Ddx43

DIOPT Version :9

• Sequence 1: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: XP_003750593.1
• Gene: Ddx43 / 682138
• RGDID: 1586947
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 650
• Identity: 314/650 - (48%)
• Similarity: 417/650 - (64%)
• Gaps: 63/650 - (9%)

  Fly    57 AKRNDYGGGRRDNRDNYGAGHRDSRDSAGGGGGDFSE-----------------SLSIASEMVGK 104
            |.|....|.|...|.....|:|..|..:.|.||.:.|                 ...:.:::||.
  Rat    16 ASRRSSTGSRGAERTATEEGNRRGRVGSRGAGGGWREPAGAAEATAASRREPPLCFGVKNDVVGA 80

  Fly   105 VIGRGGSNISRIQNDFNVRVKLDK--CDLIVKITG--SIQS---NVIDAINHVRKQVTNSGDRGQ 162
            |||||||.|..|||..|.|:::.|  .:..:||.|  ::|:   .|||  |.|:||
  Rat    81 VIGRGGSKIREIQNTTNTRIQVIKGNPEAEIKIFGNKAMQTKAKTVID--NVVKKQ--------- 134

  Fly   163 DRDNRDHGSNERYDGGGYDRYKGNSYEFNPT------SSESNKDNGDLTGIIDWEALNKASIAAT 221
                      :.|..|    ::.:...|.||      :|||..|:..|   |||:.:.:.::...
  Rat   135 ----------QNYIPG----HRVDIIAFQPTVGTDTSTSESVTDDQPL---IDWDQIREDALKWE 182

  Fly   222 AARWSKCPPLTKNFYKEAPEVANLTKSEIERIREENNKITVSYVFEPKEGETSPPIPNPVWTFEQ 286
            ..:|:..||:.||||.|:...:::::.:|:..|:||..||..   :.|:|| ..|||||:..||.
  Rat   183 KKKWADLPPIKKNFYIESATTSSMSQVQIDNWRKENFNITCD---DLKDGE-KRPIPNPICKFED 243

  Fly   287 CFAEYPDMLEEITKMGFSKPSPIQSQAWPILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQSTP 351
            .|..||:::|.|.:.||.||:|||||||||:|||.|:||:|||||||||::|:||.||.:.|...
  Rat   244 AFHSYPEVMENIKRAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLSYLMPGFIHLDSQPLA 308

  Fly   352 RGTRGGANVLVLAPTRELALQIEMEVKKYSFRGMKAVCVYGGGNRNMQISDLERGAEIIICTPGR 416
            |..|.|..:|||.||||||||:|.|..|||:..:|:|||||||:|:.||.|:.:|.:|||.||||
  Rat   309 REQRNGPGMLVLTPTRELALQVEAECSKYSYGDLKSVCVYGGGDRDGQIQDVSKGVDIIIATPGR 373

  Fly   417 LNDLIMANVIDVSTITYLVLDEADRMLDMGFEPQIRKVMLDIRPDRQTIMTSATWPPGVRRLAQS 481
            ||||.|.|.:::.::|||||||||:||||||||||.|::||:||||||||||||||..|||||||
  Rat   374 LNDLQMNNFVNLKSVTYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTIMTSATWPYAVRRLAQS 438

  Fly   482 YMKNPIQVCVGSLDLAATHSVKQIIKLMEDDMDKFNTITSFVKNMSSTDKIIIFCGRKVRADDLS 546
            |:|.|:.|.||:|||.|..:|||.| ::..:.:|...|.:|::|||..||:|:|..||..||.||
  Rat   439 YLKEPMIVYVGTLDLVAVSTVKQNI-IITTEEEKRTHIQTFLENMSPKDKVIVFVSRKAVADHLS 502

  Fly   547 SELTLDGFMTQCIHGNRDQMDREQAIADIKSGVVRILVATDVASRGLDIEDITHVINYDFPHNIE 611
            |:|.|.....:.:||||:|.|||:|:.:.|:|.||||:|||:||||||:.|||||.|||||.|||
  Rat   503 SDLILRHISVESLHGNREQSDREKALENFKTGKVRILIATDLASRGLDVHDITHVYNYDFPRNIE 567

  Fly   612 EYVHRVGRTGRAGRQGTSISFFTREDWAMAKELIEILQEAEQEVPDELHNMARRFKAMKDKRAAE 676
            ||||||||||||||.|.||:..||.||.:|.|||.||:.|.|.:|:||..||.|:||.|.||..|
  Rat   568 EYVHRVGRTGRAGRTGMSITLITRNDWRIATELINILERANQNIPEELVLMAERYKANKLKREME 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH-I	92..150	CDD:238053	25/81 (31%)
		DEADc	288..489	CDD:238167	130/200 (65%)
		DEXDc	298..505	CDD:214692	135/206 (66%)
		Helicase_C	514..624	CDD:278689	67/109 (61%)
Ddx43	XP_003750593.1	KH-I	68..133	CDD:412160	25/66 (38%)
		PTZ00110	153..642	CDD:240273	269/487 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	240	1.000	Domainoid score	I2193
eggNOG	1	0.900	-	-		E2759_KOG0336
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56814
Inparanoid	1	1.050	561	1.000	Inparanoid score	I1056
OMA	1	1.010	-	-		QHG45820
OrthoDB	1	1.010	-	-		D257031at33208
OrthoFinder	1	1.000	-	-		FOG0000439
OrthoInspector	1	1.000	-	-		oto96949
orthoMCL	1	0.900	-	-		OOG6_106450
Panther	1	1.100	-	-	O	PTHR47958
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4523
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.880