Protein Alignment CG7878 and Ddx17

DIOPT Version :9

• Sequence 1: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_951062.1
• Gene: Ddx17 / 67040
• MGIID: 1914290
• Length: 652
• Species: Mus musculus
• Alignment Length: 576
• Identity: 232/576 - (40%)
• Similarity: 330/576 - (57%)
• Gaps: 87/576 - (15%)

  Fly   158 GDRGQDRDNRDHGSNERYDGGGYDRYKGNSYEFNPTSSESNKDNGDLTGIIDWEALNKASIAATA 222
            |||.:|||.           ||:....|:..   |.....|..          |.|.|
Mouse     7 GDRDRDRDR-----------GGFGARGGSGL---PPKKFGNPG----------ERLRK------- 40

  Fly   223 ARW--SKCPPLTKNFYKEAPEVANLTKSEIERIREENNKITVSYVFEPKEGETSPPIPNPVWTFE 285
            .:|  |:.|...||||.|.||||.||..|::.:|.: .:|||      :.|:.   .|.||:.|.
Mouse    41 KKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRK-KEITV------RGGDV---CPKPVFAFH 95

  Fly   286 QCFAEYPD-MLEEITKMGFSKPSPIQSQAWPILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQS 349
            .  |.:|. :::.:....|::|:|||.|.:|:.|.|.||:||||||:|||||:|||.::|..:|
Mouse    96 H--ANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQ- 157

  Fly   350 TPRGTRG-GANVLVLAPTRELALQIEMEVKKY-SFRGMKAVCVYGGGNRNMQISDLERGAEIIIC 412
             |...|| |...||||||||||.|::.....| ....:|:.|:|||..:..||.|||||.||.|.
Mouse   158 -PYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIA 221

  Fly   413 TPGRLNDLIMANVIDVSTITYLVLDEADRMLDMGFEPQIRKVMLDIRPDRQTIMTSATWPPGVRR 477
            |||||.|.:.:...::...||||||||||||||||||||||::..|||||||:|.|||||..||:
Mouse   222 TPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQ 286

  Fly   478 LAQSYMKNPIQVCVGSLDLAATHSVKQIIKL-MEDDMDKFNTITSFVKNM--SSTDKIIIFCGRK 539
            ||:.::::..|:.||:|:|:|.|::.||:.: ||.:.|  :.:...::.:  ...:|.|||...|
Mouse   287 LAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKD--HKLIQLMEEIMAEKENKTIIFVETK 349

  Fly   540 VRADDLSSELTLDGFMTQCIHGNRDQMDREQAIADIKSGVVRILVATDVASRGLDIEDITHVINY 604
            .|.|||:..:..||:...||||::.|.:|:..:.:.:||...||:||||||||||:||:..||||
Mouse   350 RRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINY 414

  Fly   605 DFPHNIEEYVHRVGRTGRAGRQGTSISFFTREDWAMAKELIEILQEAEQEVPDELHNMARRFKAM 669
            |:|::.|:||||:|||.|:..:||:.:|||..:...|:|||::|:||.|.:..:|..:.
Mouse   415 DYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLV------ 473

  Fly   670 KDKRAAEGGGFGGRGG-----------------------RFGGGRGGGRRNFDQFQ 702
             |.|.  |||.||:||                       |..|.:.||||:...::
Mouse   474 -DHRG--GGGGGGKGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSTSYR 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH-I	92..150	CDD:238053
		DEADc	288..489	CDD:238167	105/203 (52%)
		DEXDc	298..505	CDD:214692	110/208 (53%)
		Helicase_C	514..624	CDD:278689	49/111 (44%)
Ddx17	NP_951062.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		12/54 (22%)
		DEXDc	32..502	CDD:331760	216/511 (42%)
		Q motif	92..120		7/29 (24%)
		DEAD box	246..249		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	585..652
		Interaction with YAP1. /evidence=ECO:0000250|UniProtKB:Q92841	641..649

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S387
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000439
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860