DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7878 and bel

DIOPT Version :9

Sequence 1:	NP_649767.1	Gene:	CG7878 / 40959	FlyBaseID:	FBgn0037549	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_001262379.1	Gene:	bel / 45826	FlyBaseID:	FBgn0263231	Length:	801	Species:	Drosophila melanogaster

Alignment Length:	760	Identity:	244/760 - (32%)
Similarity:	357/760 - (46%)	Gaps:	204/760 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 RDGNSR-------AYKGDRNDY----GGEGRGYRAKRNDY-----GGGRRDN----RDNYGAGHR 78
            |.||.|       ..:|...:|    ||.|||:..:..||     |||||..    .|||..|..
  Fly    79 RSGNPRQETRDPQQSRGGGGEYRRGGGGGGRGFNRQSGDYGYGSGGGGRRGGGGRFEDNYNGGEF 143

  Fly    79 DSR------DSAGGGGGDFSESLSIASEMVGKVIGRG----------GSNISRIQNDFNVRVKLD 127
            |||      .|.|||||             |:..|||          |||::
  Fly   144 DSRRGGDWNRSGGGGGG-------------GRGFGRGPSYRGGGGGSGSNLN------------- 182

  Fly   128 KCDLIVKITGSIQSNVIDAINHVRKQVTNSGDRGQDRD----------------NRDHGSNERYD 176
                        :....|.....::|..|  ||.|:.:                ||.:.:.....
  Fly   183 ------------EQTAEDGQAQQQQQPRN--DRWQEPERPAGFDGSEGGQSAGGNRSYNNRGERG 233

  Fly   177 GGGYD-RYK---GNSYEFNPTSSESNKDNGDLTGIIDWEALNKASIAATAARWSKCPPLTKNFYK 237
            ||||: |:|   |::.::....:...:...:|.|           :..|...:.|        |:
  Fly   234 GGGYNSRWKEGGGSNVDYTKLGARDERLEVELFG-----------VGNTGINFDK--------YE 279

  Fly   238 EAPEVANLTKSEIERIREENNKITVSYVFEPKEGETSPPIPNPVWTFEQCFAEYPDMLEEITKMG 302
            :.|..|.                          |:..||   .:.:|:..      .|.||.:..
  Fly   280 DIPVEAT--------------------------GQNVPP---NITSFDDV------QLTEIIRNN 309

  Fly   303 -----FSKPSPIQSQAWPILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQ----STPRGTRGGA 358
                 :.||:|:|..|.||::.|.|::..||||:|||.|||:| :::..|:    ..|:.||..:
  Fly   310 VALARYDKPTPVQKHAIPIIINGRDLMACAQTGSGKTAAFLVP-ILNQMYELGHVPPPQSTRQYS 373

  Fly   359 N------VLVLAPTRELALQIEMEVKKYSFRG-MKAVCVYGGGNRNMQISDLERGAEIIICTPGR 416
            .      .||||||||||.||..|.||:::|. |:...:|||.|.:.|:.:|:||..:|:.||||
  Fly   374 RRKQYPLGLVLAPTRELATQIFEEAKKFAYRSRMRPAVLYGGNNTSEQMRELDRGCHLIVATPGR 438

  Fly   417 LNDLIMANVIDVSTITYLVLDEADRMLDMGFEPQIRKVM--LDIRP--DRQTIMTSATWPPGVRR 477
            |.|:|....:.:..|.:|||||||||||||||||||:::  |::.|  .|||:|.|||:|..::.
  Fly   439 LEDMITRGKVGLENIRFLVLDEADRMLDMGFEPQIRRIVEQLNMPPTGQRQTLMFSATFPKQIQE 503

  Fly   478 LAQSYMKNPIQVCVGSLDLAATHSVKQIIKLMEDD-----MDKFNTI---TSFVKNMSSTDKIII 534
            ||..::.|.|.:.||.:...:.:..:.|:.:.|.|     :|..::|   ..:.|:..:    :|
  Fly   504 LASDFLSNYIFLAVGRVGSTSENITQTILWVYEPDKRSYLLDLLSSIRDGPEYTKDSLT----LI 564

  Fly   535 FCGRKVRADDLSSELTLDGFMTQC------IHGNRDQMDREQAIADIKSGVVRILVATDVASRGL 593
            |...|..||      :|:.|:.||      |||:|.|.:||:|:...:||...|||||.||:|||
  Fly   565 FVETKKGAD------SLEEFLYQCNHPVTSIHGDRTQKEREEALRCFRSGDCPILVATAVAARGL 623

  Fly   594 DIEDITHVINYDFPHNIEEYVHRVGRTGRAGRQGTSISFFTREDWAMAKELIEILQEAEQEVPDE 658
            ||..:.||||:|.|.::||||||:|||||.|..|.:.|||..::..:..:|:|:|.|.:||:|..
  Fly   624 DIPHVKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATSFFNEKNRNICSDLLELLIETKQEIPSF 688

  Fly   659 LHNMARRFKAMKDKRAAEGGGFGGRGGRFG--------GGRGGGR 695
            :.:|:........|||..||| |..||.||        ||.||||
  Fly   689 MEDMSSDRGHGGAKRAGRGGG-GRYGGGFGSRDYRQSSGGGGGGR 732

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH-I	92..150	CDD:238053	8/67 (12%)
		DEADc	288..489	CDD:238167	94/220 (43%)
		DEXDc	298..505	CDD:214692	94/226 (42%)
		Helicase_C	514..624	CDD:278689	51/118 (43%)
bel	NP_001262379.1	DEADc	297..516	CDD:238167	95/225 (42%)
		DEXDc	315..529	CDD:214692	93/214 (43%)
		Helicase_C	538..654	CDD:278689	52/125 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451481
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940