DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7878 and abs

DIOPT Version :9

Sequence 1:	NP_649767.1	Gene:	CG7878 / 40959	FlyBaseID:	FBgn0037549	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_524220.1	Gene:	abs / 40530	FlyBaseID:	FBgn0015331	Length:	619	Species:	Drosophila melanogaster

Alignment Length:	590	Identity:	176/590 - (29%)
Similarity:	295/590 - (50%)	Gaps:	57/590 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 VRVKLDKCDLIVKITGSIQSNVIDAINHVRKQVTNSGDRGQDRDNRDHGS---NERYDGGGYDRY 183
            |.||..|...::|:     ..::..::...:..::|.:..:|.....|..   ..:|:....|::
  Fly    28 VPVKERKKQHMIKL-----GRIVQLVSETAQPKSSSENENEDDSQGAHDVETWGRKYNISLLDQH 87

  Fly   184 K-----GNSYEFNPTSSESNKDNGDLTGIIDWEALNKASIAATAARWSKCPPLTKNFYKEAPEVA 243
            .     ..:.:.:....:..::...:..|...:||...:..|...::.:  |: |..:|....:.
  Fly    88 TELKKIAEAKKLSAVEKQLREEEKIMESIAQQKALMGVAELAKGIQYEQ--PI-KTAWKPPRYIR 149

  Fly   244 NLTKSEIERIREENNKITVSYVFEPKEGETSPPIPNPVWTFEQCFAEYP-DMLEEITKMGFSKPS 307
            .:::.|.|.:|.| .:|.|       ||||..|   |:.:|.:  .::| .:|..:...|...|:
  Fly   150 EMSEEEREAVRHE-LRILV-------EGETPSP---PIRSFRE--MKFPKGILNGLAAKGIKNPT 201

  Fly   308 PIQSQAWPILLQGHDMIGIAQTGTGKTLAFLLPGM---IHTEYQSTPRGTRGGANVLVLAPTREL 369
            |||.|..|.:|.|.|:||||.||:||||.|:||.:   :..|| |.|.....|...|::.|:|||
  Fly   202 PIQVQGLPTVLAGRDLIGIAFTGSGKTLVFVLPVIMFALEQEY-SLPFERNEGPYGLIICPSREL 265

  Fly   370 ALQIEMEVKKYSFR----GMKAV--CVYGGGNRNMQISD----LERGAEIIICTPGRLNDLIMAN 424
            |.|....::.||..    ||..:  |:..||   :.:|:    :.||..|::.|||||.|::...
  Fly   266 AKQTHEIIQHYSKHLQACGMPEIRSCLAMGG---LPVSEALDVISRGVHIVVATPGRLMDMLDKK 327

  Fly   425 VIDVSTITYLVLDEADRMLDMGFEPQIRKVMLDIRPDRQTIMTSATWPPGVRRLAQSYMKNPIQV 489
            ::.:....||.:||||||:|||||..:|.:....:..|||::.|||.|..::..|:|.:..|:.:
  Fly   328 ILTLDMCRYLCMDEADRMIDMGFEEDVRTIFSFFKGQRQTLLFSATMPKKIQNFARSALVKPVTI 392

  Fly   490 CVGSLDLAATHSVKQIIKLMEDDMDKFNTITSFVKNMSSTDKIIIFCGRKVRADDLSSELTLDGF 554
            .||... ||:.:|.|.::.::.:......:....|   :...::||..:|...|.:...|.|.|.
  Fly   393 NVGRAG-AASMNVTQQVEYVKQEAKVVYLLDCLQK---TAPPVLIFAEKKQDVDCIHEYLLLKGV 453

  Fly   555 MTQCIHGNRDQMDREQAIADIKSGVVRILVATDVASRGLDIEDITHVINYDFPHNIEEYVHRVGR 619
            ....|||.:||.:|.:|:...:.|...:||||||||:|||..::.||||||.|.:||.||||:||
  Fly   454 EAVAIHGGKDQEERSRAVDAYRVGKKDVLVATDVASKGLDFPNVQHVINYDMPDDIENYVHRIGR 518

  Fly   620 TGRAGRQGTSISFFTR-EDWAMAKELIEILQEAEQEVPDELHNMARRFKAMK-DKRAAEG----G 678
            |||:..:|.:.:...: .:.::..:|..:|.|.:|||||.|..:|...:... |...:.|    |
  Fly   519 TGRSNTKGLATTLINKTTEQSVLLDLKHLLIEGKQEVPDFLDELAPETEHQHLDLGDSHGCTYCG 583

  Fly   679 GFGGR 683
            |.|.|
  Fly   584 GLGHR 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH-I	92..150	CDD:238053	5/27 (19%)
		DEADc	288..489	CDD:238167	78/214 (36%)
		DEXDc	298..505	CDD:214692	81/219 (37%)
		Helicase_C	514..624	CDD:278689	45/109 (41%)
abs	NP_524220.1	DEADc	179..393	CDD:238167	79/219 (36%)
		DEXDc	192..397	CDD:214692	78/208 (38%)
		Helicase_C	414..523	CDD:278689	45/111 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451496
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940