DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7878 and Dbp21E2

DIOPT Version :9

Sequence 1:	NP_649767.1	Gene:	CG7878 / 40959	FlyBaseID:	FBgn0037549	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_608544.1	Gene:	Dbp21E2 / 33254	FlyBaseID:	FBgn0086130	Length:	536	Species:	Drosophila melanogaster

Alignment Length:	412	Identity:	116/412 - (28%)
Similarity:	195/412 - (47%)	Gaps:	56/412 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   291 YPDMLEEI-TKMGFSKPSPIQSQAWPILLQGHDMIGIAQTGTGKTLAFLLPGM-------IHTEY 347
            :|.:||.: .::|....:.||.|..|::......:..|:||.|||:.:|||.:       :.||.
  Fly   116 HPQLLENLRVELGIKLLTGIQKQGMPVVHGNEHCLIAAETGCGKTITYLLPIVDKLLQKEVVTER 180

  Fly   348 Q-STPRGTRGGANVLVLAPTRELALQIEMEVKKYSFRG--MKAVCVYGGGNRNMQISDLERGAEI 409
            : :|||       ||:|.|.||||.||....:|.: :|  :|...:.||..:.:.::......:|
  Fly   181 KLNTPR-------VLILTPGRELATQIAGVTEKLT-QGTNLKVQSLLGGNTKQLMMNPQFEEVDI 237

  Fly   410 IICTPGRLNDLIMANVIDVSTITYLVLDEADRMLDMGFEPQIRKVM------LDIRPD--RQTIM 466
            ::.|.|.|:.|:...:..:..:.:|||||||.:||..|..::...:      |..:.|  .|.|:
  Fly   238 LVATLGALSKLVTTGIYRMEQVRHLVLDEADTLLDDTFTDKLSYFLRRFPFHLVQKEDAGTQMIL 302

  Fly   467 TSATWPPGVRRLAQSYMK-NPIQVCVG-SLDLAATHSVKQIIKLMEDDMDKFNTITSFVK-NMSS 528
            .|||.|...|.:....:. :.|:..|. .|....:|..::.::|.:  .|:..|:.|.|| :::.
  Fly   303 ASATMPTNTREILHKVIDVDTIREVVSPHLHRLMSHVTQKFLRLSK--ADRPATLLSLVKHDLAK 365

  Fly   529 TDKIIIFCGRKVRADDLSSELTLDGFMTQCIHGNRDQMDR------EQAIADIKSGVVRILVATD 587
            ...:|:|..:...:|.:|..|...|  ..|::.|.|.:.:      ||    .::|...:|..||
  Fly   366 RRPLIVFSNKSTTSDFVSIFLNNSG--VNCLNLNGDMLMKIRLGRFEQ----FQNGHCDVLSTTD 424

  Fly   588 VASRGLDIEDITHVINYDFPHNIEEYVHRVGRTGRAGRQGTSISFFTREDWAMAKELIEILQEAE 652
            |.|||||.....||:|:|||.::.:|:||.||.||.|..          |.|:...||.  ...|
  Fly   425 VGSRGLDTTRARHVVNFDFPLHVSDYIHRCGRIGRVGNM----------DKALVTNLIS--SRRE 477

  Fly   653 QEVPDELHNMARRFKAMKDKRA 674
            .:|...:.:.||....:.|..|
  Fly   478 IDVVQRIEHAARTGGLLPDVNA 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH-I	92..150	CDD:238053
		DEADc	288..489	CDD:238167	62/217 (29%)
		DEXDc	298..505	CDD:214692	62/227 (27%)
		Helicase_C	514..624	CDD:278689	39/116 (34%)
Dbp21E2	NP_608544.1	P-loop_NTPase	113..314	CDD:304359	61/205 (30%)
		DEXDc	126..330	CDD:214692	60/211 (28%)
		HELICc	343..462	CDD:238034	40/126 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451486
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930