DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7878 and CG32344

DIOPT Version :9

Sequence 1:	NP_649767.1	Gene:	CG7878 / 40959	FlyBaseID:	FBgn0037549	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_612028.4	Gene:	CG32344 / 326208	FlyBaseID:	FBgn0052344	Length:	827	Species:	Drosophila melanogaster

Alignment Length:	373	Identity:	118/373 - (31%)
Similarity:	204/373 - (54%)	Gaps:	17/373 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 DMLEEITKMGFSKPSPIQSQAWPILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQSTPRGTRGG 357
            ::::.|||.|:..|:|||.:..|::|:|.|::.:|:||:|||..||:|  :..:.|.  |....|
  Fly    49 ELIKGITKRGYKVPTPIQRKTIPLILEGRDVVAMAKTGSGKTACFLIP--LFEKLQR--REPTKG 109

  Fly   358 ANVLVLAPTRELALQIEMEVKKYS-FRGMKAVCVYGGGNRNMQISDLERGAEIIICTPGRLNDLI 421
            |..|:|:||||||:|....:|:.. |..:|::.|.||.:.:.|.|.:....::|:.||||...|.
  Fly   110 ARALILSPTRELAVQTYKFIKELGRFMELKSILVLGGDSMDSQFSAIHTCPDVIVATPGRFLHLC 174

  Fly   422 MANVIDVSTITYLVLDEADRMLDMGFEPQIRKVMLDIRPDRQTIMTSATWPPGVRRLAQSYMKNP 486
            :...:.:::|.|:|.|||||:.:|||..|:.:.:..:...|||:|.|||.|..:...|::.:.:|
  Fly   175 VEMDLKLNSIEYVVFDEADRLFEMGFGEQLNETLHRLPSSRQTVMFSATLPKLLVEFARAGLNDP 239

  Fly   487 IQVCVGSLDLAATHSVKQIIKLM--EDDMDKFNTITSFVKNMSST-DKIIIFCGRKVRADDLSSE 548
            :.:   .||:.:.......:|.:  ..| |::..:...:|.:... .:.::|.|.:...:.:|..
  Fly   240 VLI---RLDVESKLPDALALKFLYCRPD-DRYTALVVLLKYVIPVQSQTVVFAGTQHHVELISYI 300

  Fly   549 LTLDGFMTQCIHGNRDQMDREQAIADIKSGVVRILVATDVASRGLDIEDITHVINYDFPHNIEEY 613
            ||..|.....::.:.|...|:...|...:..|.:|:.||||:||:||..:..|:|..||...:.:
  Fly   301 LTEAGISNASVYSSLDPAARKINTAKFVNKKVSVLIVTDVAARGIDIPSLDFVVNLHFPGKPKLF 365

  Fly   614 VHRVGRTGRAGRQGTSISFFTREDWAMAKELIEILQEAEQEVPDELHN 661
            ||||||..||||.||:.|..:.:|.|...:|...|..     |..:|:
  Fly   366 VHRVGRCARAGRTGTAYSIVSTDDTAHLLDLHLFLNR-----PFNIHD 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH-I	92..150	CDD:238053
		DEADc	288..489	CDD:238167	70/196 (36%)
		DEXDc	298..505	CDD:214692	72/207 (35%)
		Helicase_C	514..624	CDD:278689	32/110 (29%)
CG32344	NP_612028.4	DEADc	41..243	CDD:238167	70/200 (35%)
		DEXDc	54..243	CDD:214692	70/195 (36%)
		HELICc	263..384	CDD:238034	38/121 (31%)
		DBP10CT	666..721	CDD:285373
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451485
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930