Protein Alignment CG7878 and ddx46

DIOPT Version :10

• Sequence 1: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_001019988.2
• Gene: ddx46 / 321948
• ZFINID: ZDB-GENE-030131-667
• Length: 1035
• Species: Danio rerio
• Alignment Length: 695
• Identity: 218/695 - (31%)
• Similarity: 338/695 - (48%)
• Gaps: 108/695 - (15%)

  Fly     4 LDWDDPNYVEKPAVHQEYSKPNNKYERSIRRDGNSRAYKGDRNDYGGEGRGYRAKRNDYGGGRRD 68
            |:.||.:..|.||              .:..||:..    :..|...|.........:..|...|
Zfish   168 LEDDDDDDEEAPA--------------PVEPDGDDE----EEQDKAAEAEESERMEEEEVGEEVD 214

  Fly    69 NRDNYGAGHRDSRDSAGGGGGDFSESLSIASEMVGKVIGRGGSNISRIQNDFNVRVKLDKCDLIV 133
            ..|.|....::.......|            .|.|....:||.:::::.    ..||..|.....
Zfish   215 PLDAYMEEVKEEVKKFNMG------------TMKGANDKKGGMSVTKVV----TVVKTKKMPHAT 263

  Fly   134 KITGSIQSNVIDAINHVRKQVTNSGDRGQDRDNRDHGSNERYDGGGYDRYKGNSYEFNPTSSESN 198
            |..|.:..|                    |:|..::.|.|
Zfish   264 KKKGELMEN--------------------DQDAMEYSSEE------------------------- 283

  Fly   199 KDNGDL-TGIIDWEALNKASIAATAARWSKCPPLTKNFYKEAPEVANLTKSEIERIREENNKITV 262
             :..|| |.:..::...:..:.....:..:..|..||||.|.||:|.::..|:...|.|...|:|
Zfish   284 -EEVDLQTALTGFQTKQRKVLEPVDHQKIQYEPFRKNFYVEVPELARMSPEEVSEYRLELEGISV 347

  Fly   263 SYVFEPKEGETSPPIPNPVWTFEQCFAEYPDMLEEITKMGFSKPSPIQSQAWPILLQGHDMIGIA 327
            .          ....|.|:.|:.||.... .:|..:.|..:.||:|||:||.|.::.|.|:||||
Zfish   348 K----------GKGCPKPIKTWVQCGISM-KVLNALKKHNYEKPTPIQAQAIPAIMSGRDLIGIA 401

  Fly   328 QTGTGKTLAFLLPGMIHTEYQSTPRGTRGGANVLVLAPTRELALQIEMEVKKYS-FRGMKAVCVY 391
            :||:|||:|||||...|. ....|.|...|...:::.|||||||||..|.||:| ...::.||||
Zfish   402 KTGSGKTIAFLLPMFRHI-LDQRPVGEAEGPLAVIMTPTRELALQITKECKKFSKSLALRVVCVY 465

  Fly   392 GGGNRNMQISDLERGAEIIICTPGRLNDLIMAN---VIDVSTITYLVLDEADRMLDMGFEPQIRK 453
            ||...:.||::|:||||||:|||||:.|::.||   |.::..:||:|:||||||.|||||||:.:
Zfish   466 GGTGISEQIAELKRGAEIIVCTPGRMIDMLGANNGRVTNLRRVTYVVIDEADRMFDMGFEPQVMR 530

  Fly   454 VMLDIRPDRQTIMTSATWPPGVRRLAQSYMKNPIQVCVGSLDLAATHSVKQIIKLMEDDMDKFNT 518
            ::.::||||||:|.|||:|..:..||:..:..|::|.||...:..: .|:|.:.::|:: .||..
Zfish   531 IVDNVRPDRQTVMFSATFPRTMEALARRILSKPVEVQVGGRSVVCS-DVEQHVIVIEEE-KKFLK 593

  Fly   519 ITSFVKNMSSTDKIIIFCGRKVRADDLSSELTLDGFMTQCIHGNRDQMDREQAIADIKSGVVRIL 583
            :...:.:......:|||..::..||.|..:|....:....:||..||.||:..|.|.|:|..|:|
Zfish   594 LLEILGHYQEKGSVIIFVDKQEHADGLLKDLMKASYPCMSLHGGIDQYDRDSIINDFKNGACRLL 658

  Fly   584 VATDVASRGLDIEDITHVINYDFPHNIEEYVHRVGRTGRAGRQGTSISFFTREDWAMAKELIEIL 648
            |||.||:||||::.:..|:||..|::.|:||||.|||||||.:|.:.:|.|......:.::::.|
Zfish   659 VATSVAARGLDVKQLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEGQARYSGDILKAL 723

  Fly   649 QEAEQEVPDELHNMARRFKAMKDKRAAEG------GGFGGRGGRF 687
            :.:...||.||..:...|   |:::.|||      .||.|:|.:|
Zfish   724 ELSGSSVPAELEQLWTNF---KEQQKAEGKIIKSSSGFSGKGFKF 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH_1	92..152	CDD:459630	10/59 (17%)
		DEAD-like_helicase_N	174..663	CDD:475120	179/493 (36%)
ddx46	NP_001019988.2	Q motif	357..385		9/28 (32%)
		DEAD box	514..517		2/2 (100%)