Protein Alignment CG7878 and Ddx3x

DIOPT Version :10

• Sequence 1: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_001385681.1
• Gene: Ddx3x / 317335
• RGDID: 1564771
• Length: 662
• Species: Rattus norvegicus
• Alignment Length: 750
• Identity: 230/750 - (30%)
• Similarity: 333/750 - (44%)
• Gaps: 199/750 - (26%)

  Fly     9 PNYVEKPAVHQEYSKPNNKYERSIRRDGNSRAYK--GDRNDYGGEGRGYRAKRNDYGGGRRDNRD 71
            |:...:.|....|.|.::.:..|..:|    ||.  |.|    |:.||..:...|.|.|.|...|
  Rat    41 PHLRNREATKGFYDKDSSGWSSSKDKD----AYSSFGSR----GDSRGKSSFFGDRGSGSRGRFD 97

  Fly    72 NYGAGHRDSRDSAGGGGGDFSESLSIASEMVGKVIGRGGSNISRIQNDFNVRVKLDKCDLIVKIT 136
            :.|.|..|..    ||.||.|.        .|| ..|||::
  Rat    98 DRGRGDYDGI----GGRGDRSG--------FGK-FERGGNS------------------------ 125

  Fly   137 GSIQSNVIDAINHVRKQVTNSGDRGQDRDNRDHGSNERYDGGGYDRYKGNSYEFNPTSSESNKD- 200
                                   |..|:.:.|..|...                 |.|....::
  Rat   126 -----------------------RWCDKSDEDDWSKPL-----------------PPSERLEQEL 150

  Fly   201 -NGDLTGIIDWEALNKASIAATAARWSKCPPLTKNFYKEAPEVANLTKSEIERIREENNKITVSY 264
             :|..|| |::|..:...:.||.   :.|||..::|            |::|.     .:|.:..
  Rat   151 FSGGNTG-INFEKYDDIPVEATG---NNCPPHIESF------------SDVEM-----GEIIMGN 194

  Fly   265 VFEPKEGETSPPIPNPVWTFEQCFAEYPDMLEEITKMGFSKPSPIQSQAWPILLQGHDMIGIAQT 329
            :                               |:|:  :::|:|:|..|.||:.:..|::..|||
  Rat   195 I-------------------------------ELTR--YTRPTPVQKHAIPIIKEKRDLMACAQT 226

  Fly   330 GTGKTLAFLLPGMIHTEYQSTP---------RGTRGGAN----VLVLAPTRELALQIEMEVKKYS 381
            |:|||.||||| ::...|...|         .|..|...    .||||||||||:||..|.:|:|
  Rat   227 GSGKTAAFLLP-ILSQIYADGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFS 290

  Fly   382 FRGMKAVC-VYGGGNRNMQISDLERGAEIIICTPGRLNDLIMANVIDVSTITYLVLDEADRMLDM 445
            :|.....| ||||.....||.|||||..:::.|||||.|::....|.:....|||||||||||||
  Rat   291 YRSRVRPCVVYGGAEIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDM 355

  Fly   446 GFEPQIRKVM-LDIRPD---RQTIMTSATWPPGVRRLAQSYMKNPIQVCVGSLDLAATHSVKQII 506
            |||||||::: .|..|.   |.|:|.|||:|..::.||:.::...|.:.||.:...:.:..::::
  Rat   356 GFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV 420

  Fly   507 KLMEDDMDKFNTITSFVKNMSSTDKIIIFCGRKVRADDLSSELTLDGFMTQCIHGNRDQMDREQA 571
            .:  :::||.:.:...:.........::|...|..||.|...|..:|:....|||:|.|.|||:|
  Rat   421 WV--EEIDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEA 483

  Fly   572 IADIKSGVVRILVATDVASRGLDIEDITHVINYDFPHNIEEYVHRVGRTGRAGRQGTSISFFTRE 636
            :...:||...|||||.||:|||||.::.||||:|.|.:|||||||:|||||.|..|.:.|||...
  Rat   484 LHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNER 548

  Fly   637 DWAMAKELIEILQEAEQEVPDELHNMA--RRFKAM---KDKRAAEGGGFGGR------------- 683
            :..:.|:|:::|.||:||||..|.|||  ..:|..   :.|.:...||||.|
  Rat   549 NINITKDLLDLLVEAKQEVPSWLENMAFEHHYKGSSRGRSKSSRFSGGFGARDYRQSSGASSSSF 613

  Fly   684 ------------GGR-----FGGGRGGGRRNFDQF 701
                        ||.     ||||..||..|.|.:
  Rat   614 SSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGY 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH_1	92..152	CDD:459630	6/59 (10%)
		DEAD-like_helicase_N	174..663	CDD:475120	176/508 (35%)
Ddx3x	NP_001385681.1	DEADc_DDX3	160..410	CDD:350809	104/303 (34%)
		SF2_C_DEAD	415..545	CDD:350174	53/131 (40%)