Protein Alignment CG7878 and ddx4

DIOPT Version :10

• Sequence 1: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: XP_073769595.1
• Gene: ddx4 / 30263
• ZFINID: ZDB-GENE-990415-272
• Length: 796
• Species: Danio rerio
• Alignment Length: 729
• Identity: 222/729 - (30%)
• Similarity: 346/729 - (47%)
• Gaps: 127/729 - (17%)

  Fly    26 NKYERSIRRDGNSRAYKGDR-NDYGGEGRGYRAKRNDYGGGRRDNRDNYGAGHRDSRDSAGGGGG 89
            |....|...:|:|....||. ...||.| |.|..|..:.|.:.:..:|...|..:..:|.|.|.|
Zfish   120 NDKSNSEGTEGSSWKMTGDSFRGRGGRG-GSRGGRGGFSGFKSEIDENGSDGGWNGGESRGKGRG 183

  Fly    90 DFSESLSIASEMVGKVIG-----RGGSNISRIQNDFNVRVKLDKCDLIVKITGSIQSNVIDAINH 149
            .|.......|.......|     :||.:..|.:..|.               |..:....|..|.
Zfish   184 GFRGGFRSGSRDENDENGNDDGWKGGESRGRGRGGFG---------------GGFRGGFRDGGNE 233

  Fly   150 VRKQVTNSGDRGQDRDNRDHGSNERYDGGGYDR--YKGNSYEFNPTSSESNK---DNGDLTGIID 209
                  ::|.||..|:|.::| |:..:|.|..|  ::|...:..  ..||.|   ..|...|..:
Zfish   234 ------DTGRRGFGRENNENG-NDEGEGRGRGRGGFRGGFRDGG--GDESGKRGFGRGGFRGRNE 289

  Fly   210 WEALNKASIAATAARWSKCPPLTKNFYKEAPEVANLTKSEIERIREENNKITVSYVFEPKEGETS 274
             |..:|.:                            |..::::...||....|.||..|...|.|
Zfish   290 -EVFSKVT----------------------------TADKLDQEGSENAGPKVVYVPPPPPEEES 325

  Fly   275 PPI------------------------PNPVWTFEQCFAEYPDML-EEITKMGFSKPSPIQSQAW 314
            ...                        |..:.|||:  |...|.| :.::|.|:.||:|:|....
Zfish   326 SIFSHYATGINFDKYDDILVDVSGSNPPKAIMTFEE--AGLCDSLSKNVSKSGYVKPTPVQKHGI 388

  Fly   315 PILLQGHDMIGIAQTGTGKTLAFLLP--------GMIHTEYQSTPRGTRGGANVLVLAPTRELAL 371
            ||:..|.|::..||||:|||.|||||        |:..:::.....     ...:::||||||..
Zfish   389 PIISAGRDLMACAQTGSGKTAAFLLPILQRFMTDGVAASKFSEIQE-----PEAIIVAPTRELIN 448

  Fly   372 QIEMEVKKYSF-RGMKAVCVYGGGNRNMQISDLERGAEIIICTPGRLNDLIMANVIDVSTITYLV 435
            ||.:|.:|::: ..::.|.||||.|....|.::.:|..::..|||||:|||....|.:|.:.|||
Zfish   449 QIYLEARKFAYGTCVRPVVVYGGINTGYTIREVLKGCNVLCATPGRLHDLIGRGKIGLSKVRYLV 513

  Fly   436 LDEADRMLDMGFEPQIRKVM----LDIRPDRQTIMTSATWPPGVRRLAQSYMK-NPIQVCVGSLD 495
            ||||||||||||||::||::    :..:.:|||:|.|||:|..::|:|..::| :.|.:.||.:.
Zfish   514 LDEADRMLDMGFEPEMRKLVASPGMPSKEERQTLMFSATYPEDIQRMAADFLKVDYIFLAVGVVG 578

  Fly   496 LAATHSVKQIIKLMEDDMDKFNTITSFVKNMSSTDKIIIFCGRKVRADDLSSELTLDGFMTQCIH 560
            .|.:...:.|:::  |...|.:.:...:: .:..::.::|...|..||.:::.|..:...|..||
Zfish   579 GACSDVEQTIVQV--DQYSKRDQLLELLR-ATGNERTMVFVETKRSADFIATFLCQEKISTTSIH 640

  Fly   561 GNRDQMDREQAIADIKSGVVRILVATDVASRGLDIEDITHVINYDFPHNIEEYVHRVGRTGRAGR 625
            |:|:|.:||:|::|.:.|...:||||.||:||||||.:.||:|:|.|.:|:|||||:|||||.|.
Zfish   641 GDREQREREKALSDFRLGQCPVLVATSVAARGLDIEQVQHVVNFDMPSSIDEYVHRIGRTGRCGN 705

  Fly   626 QGTSISFFTRE-DWAMAKELIEILQEAEQEVPDELHNMARRFKAMKDKRAAEG-GGFGGRGGRFG 688
            .|.::|||..| |..:|:.|:::|..|:|.||..|..:|         .:|.| .||..||..|.
Zfish   706 TGRAVSFFNPESDTPLARSLVKVLSGAQQVVPKWLEEVA---------FSAHGTTGFNPRGKVFA 761

  Fly   689 G--GRGGGRRNFDQ 700
            .  .|.||....|:
Zfish   762 STDSRKGGSFKSDE 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH_1	92..152	CDD:459630	9/64 (14%)
		DEAD-like_helicase_N	174..663	CDD:475120	174/533 (33%)
ddx4	XP_073769595.1	None