Protein Alignment CG7878 and ddx-23

DIOPT Version :10

• Sequence 1: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_498260.2
• Gene: ddx-23 / 175818
• WormBaseID: WBGene00017162
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 772
• Identity: 236/772 - (30%)
• Similarity: 339/772 - (43%)
• Gaps: 202/772 - (26%)

  Fly    13 EKPAVHQEYSKPN--NKYERSI----RRD--------------------GNSRAYKGDRNDYG-- 49
            :|.....|.:||.  :|.||:.    ||:                    |.:.....||.|.|
 Worm    14 KKKREEDELAKPKFLSKAERAALALKRREEEVAKLRETQKQAEEARKNWGRTEKTSDDRRDRGLD 78

  Fly    50 -GEGRGYRAKRNDYGGGRRDNRDNYGAGHRD------SRDSAGGGGGDFSESLSIASEMVGKVIG 107
             |..|....:|......|||.|:.  :|.||      |||..||...|.|.|
 Worm    79 RGNDRDRDRERERDRDRRRDRRER--SGSRDRRRRSRSRDRDGGRRRDRSRS------------- 128

  Fly   108 RGGSNISRIQNDFNVRVKLDKCDLIVKITGSIQSNVIDAINHVRKQVTNSGDRGQDRDNRDHGSN 172
                           |.:.|:                   |..||:     ||.:|.||.:..|
 Worm   129 ---------------RDRRDR-------------------NDDRKR-----DRNEDSDNEEDVS- 153

  Fly   173 ERYDGGGYDRYKGNSYEFNPTSSESNKDNG----DLTGIIDWEA--------------------L 213
             :......|||.|...|        .|..|    :...:.||:|                    .
 Worm   154 -KMADAVKDRYLGKQKE--------KKKRGRRLHEKKFVFDWDAGEDTSQDYNKLYQSRHEIQFF 209

  Fly   214 NKASIAATAARWSKCPPLTKN-FYKEAPE---VANLTKSEIERIREENNK--------------- 259
            .:.|:|.|.....|   ..|| ||:|..|   ..:..:.|:.|:.:|..|
 Worm   210 GRGSVAGTDVNAQK---KEKNSFYQEMMENRRTVDEKEQEMHRLEKELKKEKKVAHDDRHWRMKE 271

  Fly   260 -----------ITVSYVFEPKEGETSPPIPNPVWTFEQCFAEYPD-MLEEITKMGFSKPSPIQSQ 312
                       ....:....|.|.    :|.|:..:|:  |.:|| :.:.:.::|:.:|:|||.|
 Worm   272 LSEMSDRDWRIFREDFNISIKGGR----VPRPLRNWEE--AGFPDEVYQAVKEIGYLEPTPIQRQ 330

  Fly   313 AWPILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQSTPRGTRG-----GANVLVLAPTRELALQ 372
            |.||.||..|:||:|:||:|||.|||||.::.  ..|.|:..|.     |...:::|||||||.|
 Worm   331 AIPIGLQNRDVIGVAETGSGKTAAFLLPLLVW--ITSLPKMERQEHRDLGPYAIIMAPTRELAQQ 393

  Fly   373 IEMEVKKY-SFRGMKAVCVYGGGNRNMQISDLERGAEIIICTPGRLNDLIMANVIDVSTITYLVL 436
            ||.|..|: ...|:|.|.|.||.:|..|...|..|.|::|.|||||.|::....:.::..||::|
 Worm   394 IEEETNKFGKLLGIKTVSVIGGASREDQGMKLRMGVEVVIATPGRLLDVLENRYLLLNQCTYVIL 458

  Fly   437 DEADRMLDMGFEPQIRKVMLDIRPD--------------------------RQTIMTSATWPPGV 475
            |||||||||||||.::|| |:..||                          |||:|.:||....:
 Worm   459 DEADRMLDMGFEPDVQKV-LEYMPDTNMKKDTDEFDNEEALMKGFSTREKYRQTVMFTATMSSAI 522

  Fly   476 RRLAQSYMKNPIQVCVGSLDLAATHSVKQIIKLMEDDMDKFNTITSFVKNMSSTDKIIIFCGRKV 540
            .|||:.|::.|..|.:||.. ..|..|:|::.::.:|..:...:.  |........||||..:|.
 Worm   523 ERLARQYLRRPAVVHIGSAG-KPTERVEQVVYMVPEDRKRKKLVE--VLESQFQPPIIIFVNQKK 584

  Fly   541 RADDLSSELTLDGFMTQCIHGNRDQMDREQAIADIKSGVVRILVATDVASRGLDIEDITHVINYD 605
            .||.||..||..||....:||.:.|..||.|:..:|.|...||||||||.||:|::|::.|:|||
 Worm   585 GADMLSKGLTKLGFKPTVLHGGKGQDQREYALQALKEGTSDILVATDVAGRGIDVKDVSLVLNYD 649

  Fly   606 FPHNIEEYVHRVGRTGRAGRQGTSISFFTREDWAMAKELIEILQEAE-QEVPDELHN 661
            ...:||:|.||:|||||||:.|.:|:|.|.:|.|:..:|.::|.|:. ...|.||.|
 Worm   650 MAKSIEDYTHRIGRTGRAGKHGKAITFLTPDDTAVYFDLKQVLVESPVSSCPPELAN 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH_1	92..152	CDD:459630	5/59 (8%)
		DEAD-like_helicase_N	174..663	CDD:475120	193/576 (34%)
ddx-23	NP_498260.2	SrmB	304..681	CDD:440279	156/384 (41%)