Protein Alignment CG7878 and C46F11.4

DIOPT Version :10

• Sequence 1: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_497743.1
• Gene: C46F11.4 / 175469
• WormBaseID: WBGene00008119
• Length: 811
• Species: Caenorhabditis elegans
• Alignment Length: 696
• Identity: 207/696 - (29%)
• Similarity: 337/696 - (48%)
• Gaps: 107/696 - (15%)

  Fly    58 KRNDYGGGRRDNRDNYGA-GHRDSR------DSAGGGGGDFSESLSIASEMVGKVIGRGGSNISR 115
            |..:|.     |...||: ..:.||      |....||.|..:..|.:|::..
 Worm    66 KEQEYA-----NLMAYGSTSEKQSRRKRIYDDEYLEGGSDDEKPASSSSKLAA------------ 113

  Fly   116 IQNDFNVRVKLDKCDLIVKITGSIQSNVIDAINHVRKQVTNSGD---RGQDRDNRDHGSNERYDG 177
              :|.:...:||.....::...|....|.:.....||:..::.|   :|..|.:.|....:....
 Worm   114 --DDDDEEDELDAFMAGIEKQASSDKKVSEQKEKDRKEGKDTEDPSKKGLGRADIDEEDMQESLF 176

  Fly   178 GGYDRYKGNSYEFNPTSSESNKDNGDLTGIIDWEALNKASIAATAARWSK-CPPL---------- 231
            ...:.|| ..:|.:....|.::|     |.|.|.             |.| ..||
 Worm   177 KFMEEYK-EKHENDDEQLEYDED-----GNIIWS-------------WKKVIDPLPDIDHSQIQY 222

  Fly   232 ---TKNFYKEAPEVANLTKSEIERIREENNKITVSYVFEPKEGETSPPIPNPVWTFEQCFAEYPD 293
               .||||:|..::..|...::.|::...|.         :.|...|  |.||.:|.. |:....
 Worm   223 QKFNKNFYEEHEDIKRLHYMDVIRLQNTMNL---------RVGGLKP--PRPVCSFAH-FSFDKL 275

  Fly   294 MLEEITKMGFSKPSPIQSQAWPILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQSTPRGTRGGA 358
            ::|.|.|..:.:|:|||:.|.|..|.|.|::|||:||:|||.|:|.|.::|...|...:...|..
 Worm   276 LMEAIRKSEYEQPTPIQAMAIPSALSGRDVLGIAKTGSGKTAAYLWPAIVHIMDQPDLKAGEGPV 340

  Fly   359 NVLVLAPTRELALQIEMEVKKY-SFRGMKAVCVYGGGNRNMQISDLE-RGAEIIICTPGRLNDLI 421
            .|:|: ||||||:|:..|.||: ....:..:|.||||::..|.::|: .|||:::|||||:.||:
 Worm   341 AVIVV-PTRELAIQVFQEAKKFCKVYNINPICAYGGGSKWEQSNELQNEGAEMVVCTPGRIIDLV 404

  Fly   422 MANVIDVSTITYLVLDEADRMLDMGFEPQIRKVMLDIRPDRQTIMTSATWPPGVRRLAQSYMKNP 486
            .....:....|:||.||||||.|||||.|::.:...:|||||.:|.|||:...|.|||:..:.:|
 Worm   405 KMGATNFLRTTFLVFDEADRMFDMGFEAQVKSISDHVRPDRQCLMFSATFKQKVERLARDALVDP 469

  Fly   487 IQVCVGSLDLAATHSVKQIIKLMEDDMDKFNTITSFVKNMSSTDKIIIFCGRKVRADDLSSELTL 551
            :::..|.:. .|...::|.:.:|::...|.:.:...:...:|..|::||..:|:.::|::.:|.:
 Worm   470 VRIVQGEVG-EANADIEQKVFVMQNQDVKLHWLIRNLVEFASLGKVLIFVTKKLDSEDVAKKLKM 533

  Fly   552 DGFMTQCIHGNRDQMDREQAIADIKSGVVRILVATDVASRGLDIEDITHVINYDFPHNIEEYVHR 616
            ..|....:||:..|.:|.:.:...:. ..:||||||||:|||||.:|..|||:|...:|:.:|||
 Worm   534 KDFDIVLLHGDMLQAERNENLLKFRK-KSQILVATDVAARGLDISEIRTVINFDMARDIDTHVHR 597

  Fly   617 VGRTGRAGRQGTSISFFTREDWAMAKELIEILQEAEQEVPDELHNMARRFKAMKDKRAAEGG--- 678
            :|||||||.:||:.:..|.:|..|...|::.|:...||||..|.::|.:....:.:||..||
 Worm   598 IGRTGRAGHKGTAYTLVTEKDIEMVGHLVKNLESVSQEVPKPLMDLAMKSSWFRGQRAGNGGPST 662

  Fly   679 ----------GFGGRGGRFGGG---------------RGGGRRNFD 699
                      |:..:..:.|||               ||||.:..|
 Worm   663 GTQTRGRMGLGYTPKVRQVGGGATGAQFDPLKEQKSCRGGGNQTVD 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH_1	92..152	CDD:459630	7/59 (12%)
		DEAD-like_helicase_N	174..663	CDD:475120	169/504 (34%)
C46F11.4	NP_497743.1	SrmB	266..669	CDD:440279	149/406 (37%)