Protein Alignment CG7878 and glh-1

DIOPT Version :10

• Sequence 1: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_491963.1
• Gene: glh-1 / 172414
• WormBaseID: WBGene00001598
• Length: 763
• Species: Caenorhabditis elegans
• Alignment Length: 703
• Identity: 210/703 - (29%)
• Similarity: 315/703 - (44%)
• Gaps: 109/703 - (15%)

  Fly    48 YGGEGRGY--RAKRNDYGGGRRDNRDNYGAGHRDSRDSAGGGGGDFSESLSIASEMVGKVIGRGG 110
            |||...|:  ....:.:|.|.:.:......|...|....|.|||.|....|...|.     |.||
 Worm    94 YGGASSGFGGSTATSGFGSGEKSSAFGGSGGFGGSATGFGSGGGSFGGGNSGFGEG-----GHGG 153

  Fly   111 SNISRIQNDFNVRV---KLDKC-----DLIVKITGSIQSNVIDAINHVRKQVT-----NSGDRGQ 162
            .  .|..|.||.:.   :...|     :...::..:.|..     .|..::.|     ..|..|.
 Worm   154 G--ERNNNCFNCQQPGHRSSDCPEPRKEREPRVCYNCQQP-----GHTSRECTEERKPREGRTGG 211

  Fly   163 DRDNRDHGSNERYDGGGYDRYKGNSYEFNPTSSESNKDNGDLTGIIDWEALNKASIAATAARWSK 227
            .......|:|...||.|.|...|...|..|....:.|..|..:...........:......|.::
 Worm   212 FGGGAGFGNNGGNDGFGGDGGFGGGEERGPMKCFNCKGEGHRSAECPEPPRGCFNCGEQGHRSNE 276

  Fly   228 CP-------------------PLTKNFYKEAPEVANLTK-SE---IERIREENNKITVSYVFEPK 269
            ||                   |:..|.    .:|.|:.| ||   ..:..:...|:|.|
 Worm   277 CPNPAKPREGVEGEGPKATYVPVEDNM----EDVFNMQKISEGLMFNKFFDAEVKLTSS------ 331

  Fly   270 EGETSPPIPNPVWTF-EQCFAEYPDMLEEITKMGFSKPSPIQSQAWPILLQGHDMIGIAQTGTGK 333
              |.:..| .|..|| |....|  .|.:.:...|:||.:|||..|.|::.||:|::..||||:||
 Worm   332 --EKTVGI-KPCKTFAEANLTE--TMQKNVAHAGYSKTTPIQQYALPLVHQGYDIMACAQTGSGK 391

  Fly   334 TLAFLLPGMIH-TEYQSTPRGTRGGA--NVLVLAPTRELALQIEMEVKKYSFRGMKAV-CVYGGG 394
            |.|||||.|.. .:..:......||.  ..::|.||||||.||..|.:|::::.|..: .||||.
 Worm   392 TAAFLLPIMTRLIDDNNLNTAGEGGCYPRCIILTPTRELADQIYNEGRKFAYQTMMEIKPVYGGL 456

  Fly   395 NRNMQISDLERGAEIIICTPGRLNDLIMANVIDVSTITYLVLDEADRMLD-MGFEPQIRKVM-LD 457
            ........:|:||.||:.|.||:........|.:....:.||||||||:| |||...|..:: .|
 Worm   457 AVGYNKGQIEKGATIIVGTVGRIKHFCEEGTIKLDKCRFFVLDEADRMIDAMGFGTDIETIVNYD 521

  Fly   458 IRP---DRQTIMTSATWPPGVRRLAQSYMK-NPIQVCVGSLDLAATHSVKQ-------------I 505
            ..|   :|||:|.|||:|..|:..|::::: |.:.:.:..:. ||...|.|             :
 Worm   522 SMPRKENRQTLMFSATFPDSVQEAARAFLRENYVMIAIDKIG-AANKCVLQEFERCERSEKKDKL 585

  Fly   506 IKLMEDDMDKFNTITSFVKNMSSTDKIIIFCGRKVRADDLSSELTLDGFMTQCIHGNRDQMDREQ 570
            ::|:..|:|.:.|..|   ....|.|.::|..::..||.|:|.|:........|||.|:|.:|.:
 Worm   586 LELLGIDIDSYTTEKS---AEVYTKKTMVFVSQRAMADTLASILSSAQVPAITIHGAREQRERSE 647

  Fly   571 AIADIKSGVVRILVATDVASRGLDIEDITHVINYDFPHNIEEYVHRVGRTGRAGRQGTSISFFTR 635
            |:...::|...:|:||.||.|||||:.:.||||||.|.||::|:||:|||||.|..|.:.||.:
 Worm   648 ALRQFRNGSKPVLIATAVAERGLDIKGVDHVINYDMPDNIDDYIHRIGRTGRVGNSGRATSFIS- 711

  Fly   636 EDWAMAKELIEILQEAEQEVPDELHNMARRFKAMKDKRAAEGGGFGGRGGRFG 688
            ||.::..||:.:|.:|:|.|||.:             :.|.||.:|..|  ||
 Worm   712 EDCSLLSELVGVLADAQQIVPDWM-------------QGAAGGNYGASG--FG 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH_1	92..152	CDD:459630	12/67 (18%)
		DEAD-like_helicase_N	174..663	CDD:475120	173/535 (32%)
glh-1	NP_491963.1	PTZ00368	<160..278	CDD:173561	20/122 (16%)
		SrmB	342..713	CDD:440279	138/377 (37%)