Protein Alignment CG7878 and Ddx5

DIOPT Version :9

• Sequence 1: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_001342605.1
• Gene: Ddx5 / 13207
• MGIID: 105037
• Length: 615
• Species: Mus musculus
• Alignment Length: 560
• Identity: 216/560 - (38%)
• Similarity: 324/560 - (57%)
• Gaps: 70/560 - (12%)

  Fly   159 DRGQDRDNRDHGSNERYDGGGYDRYKGNSYEFNPTSSESNKDNGDLTGIIDWEALNKASIAATAA 223
            |||:||            |.|..|:                 .|..||.:..:............
Mouse     9 DRGRDR------------GFGAPRF-----------------GGSRTGPLSGKKFGNPGEKLVKK 44

  Fly   224 RWS--KCPPLTKNFYKEAPEVANLTKSEIERIREENNKITVSYVFEPKEGETSPPIPNPVWTFEQ 286
            :|:  :.|...||||:|.|::|..|..|::..| .:.:|||       .|..   .|.||..|.:
Mouse    45 KWNLDELPKFEKNFYQEHPDLARRTAQEVDTYR-RSKEITV-------RGHN---CPKPVLNFYE 98

  Fly   287 CFAEYP-DMLEEITKMGFSKPSPIQSQAWPILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQST 350
              |.:| ::::.|.:..|::|:.||:|.||:.|.|.||:|:||||:||||::|||.::|..:|
Mouse    99 --ANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQ-- 159

  Fly   351 PRGTRG-GANVLVLAPTRELALQIEMEVKKYSFRG--MKAVCVYGGGNRNMQISDLERGAEIIIC 412
            |...|| |...||||||||||.|::....:|. |.  :|:.|:|||..:..||.|||||.||.|.
Mouse   160 PFLERGDGPICLVLAPTRELAQQVQQVAAEYC-RACRLKSTCIYGGAPKGPQIRDLERGVEICIA 223

  Fly   413 TPGRLNDLIMANVIDVSTITYLVLDEADRMLDMGFEPQIRKVMLDIRPDRQTIMTSATWPPGVRR 477
            |||||.|.:.....::...||||||||||||||||||||||::..|||||||:|.|||||..||:
Mouse   224 TPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQ 288

  Fly   478 LAQSYMKNPIQVCVGSLDLAATHSVKQIIKLMEDDMDKFNTITSFVKNMSS--TDKIIIFCGRKV 540
            ||:.::|:.|.:.:|:|:|:|.|::.||:.:.. |::|...:...::.:.|  .:|.|:|...|.
Mouse   289 LAEDFLKDYIHINIGALELSANHNILQIVDVCH-DVEKDEKLIRLMEEIMSEKENKTIVFVETKR 352

  Fly   541 RADDLSSELTLDGFMTQCIHGNRDQMDREQAIADIKSGVVRILVATDVASRGLDIEDITHVINYD 605
            |.|:|:.::..||:....|||::.|.:|:..:.:.|.|...||:||||||||||:||:..|||||
Mouse   353 RCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYD 417

  Fly   606 FPHNIEEYVHRVGRTGRAGRQGTSISFFTREDWAMAKELIEILQEAEQEVPDELHNMARRFKAMK 670
            :|::.|:|:||:|||.|:.:.||:.:|||..:.....:||.:|:||.|.:..:|      .:.::
Mouse   418 YPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKL------LQLVE 476

  Fly   671 DKRAAEGGGFGG----RGGRFGGGRGGG------RRNFDQ 700
            |:.:....|.||    |..|:..|:.||      |.|:|:
Mouse   477 DRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDR 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH-I	92..150	CDD:238053
		DEADc	288..489	CDD:238167	107/204 (52%)
		DEXDc	298..505	CDD:214692	110/209 (53%)
		Helicase_C	514..624	CDD:278689	46/111 (41%)
Ddx5	NP_001342605.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..39		11/58 (19%)
		DEXDc	6..507	CDD:331760	213/549 (39%)
		Q motif	94..122		7/29 (24%)
		DEAD box	248..251		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	477..504		7/26 (27%)
		P68HR	498..532	CDD:285323	6/19 (32%)
		P68HR	551..583	CDD:285323

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000439
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910