Protein Alignment CG7878 and LOC1280623

DIOPT Version :10

• Sequence 1: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: XP_320481.4
• Gene: LOC1280623 / 1280623
• VectorBaseID: AGAMI1_009841
• Length: 910
• Species: Anopheles gambiae
• Alignment Length: 751
• Identity: 263/751 - (35%)
• Similarity: 374/751 - (49%)
• Gaps: 166/751 - (22%)

  Fly    14 KPAVHQEY-SKPNNKYERSIRRDG-------NSRAYKG-----DRNDYGGEGRGYRAKRNDYGGG 65
            :|..:..| .:|..|....:.:.|       |:.|:.|     .:|...|.|.|   ..|.:|||
Mosquito    18 RPEKNDFYVGQPGTKPPHFMNKQGPPSIPPFNANAFGGPKPMYQQNAINGVGPG---GFNKFGGG 79

  Fly    66 RRDNRDNYGAGHRDSRDSAGGGGG-----DFSESLSIASEMVGKVIGRGGSNISRIQNDFNVRVK 125
                      |:|    :.||..|     ||...         |:.|.|||.
Mosquito    80 ----------GNR----AFGGQPGTMPKKDFGGP---------KMYGPGGSK------------- 108

  Fly   126 LDKCDLIVKITGSIQSNVIDAINHVRKQVTNSGDRGQDRDNRDHGSNERYD------GGGYDRYK 184
                                             ..|.|:.....|..::|.      ||||.  .
Mosquito   109 ---------------------------------PYGDDKPFDTFGGPKKYPTTNPGMGGGYG--M 138

  Fly   185 GNSYEFNPTSSESNKDNGDLTGIIDWEALNKASIAATAAR----------WSKCPPLTKNFYKEA 239
            ||...:....|:.|..|.|          ::|.|.:..|:          |....|..|:||...
Mosquito   139 GNRNGYGGMRSDYNGFNKD----------DRAKIQSLKAKYPGQNLMKPMWENLEPFQKDFYVPH 193

  Fly   240 PEVANLTKSEIERIREENNKITVSYVFEPKEGETSPPIPNPVWTFEQ-CFAEYPDMLEEITKMGF 303
            |.|......|::..||: .:|||.       |..   :|:|...||: .|.||  ::.||.|.||
Mosquito   194 PSVMGRAAEEVQTFREQ-MQITVM-------GNN---VPHPCQNFEEGNFPEY--VMTEIKKQGF 245

  Fly   304 SKPSPIQSQAWPILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQSTPRGTRGGANVLVLAPTRE 368
            .:|:.||||.|||.|.|.||:||||||:|||||::|||::|..:|. |.....|..|||||||||
Mosquito   246 PRPTAIQSQGWPIALSGRDMVGIAQTGSGKTLAYMLPGLVHISHQK-PLSRGEGPIVLVLAPTRE 309

  Fly   369 LALQIEMEVK---KYSFRGMKAVCVYGGGNRNMQISDLERGAEIIICTPGRLNDLIMANVIDVST 430
            ||.||:..|:   .:|...::..||:||..:..|:.|||||.|::|.|||||.|.:...:.::..
Mosquito   310 LAQQIQTVVRDFGNHSKPNIRYTCVFGGALKGPQVRDLERGVEVVIATPGRLIDFLERGITNLRR 374

  Fly   431 ITYLVLDEADRMLDMGFEPQIRKVMLDIRPDRQTIMTSATWPPGVRRLAQSYMKNPIQVCVGSLD 495
            .||||||||||||||||||||||::..||||||.:|.|||||..|:.||:.::::.||:.:|||.
Mosquito   375 CTYLVLDEADRMLDMGFEPQIRKIVEQIRPDRQVLMWSATWPKEVQTLAEDFLRDYIQINIGSLS 439

  Fly   496 LAATHSVKQIIKLMEDDMDKFNTITSFVKNMSSTD---KIIIFCGRKVRADDLSSELTLDGFMTQ 557
            |||.|::.||:.:.|:: :|...:...:|.::::|   |||||...|.:.|||...:..||:...
Mosquito   440 LAANHNIHQIVDVCEEN-EKEGKLLKLLKEIATSDATNKIIIFVETKKKVDDLLKNIVRDGYGAT 503

  Fly   558 CIHGNRDQMDREQAIADIKSGVVRILVATDVASRGLDIEDITHVINYDFPHNIEEYVHRVGRTGR 622
            .|||::.|.:|:..:.|.:.|...||||||||:||||:||:.:|||:|:|::.|:|:||:|||||
Mosquito   504 SIHGDKSQTERDYVLQDFRHGKSTILVATDVAARGLDVEDVKYVINFDYPNSSEDYIHRIGRTGR 568

  Fly   623 AGRQGTSISFFTREDWAMAKELIEILQEAEQEVPDELHNMAR----------RFKAMKDKRAAE- 676
            ..:.||:.:|||..:...|:||:.:|:||.|:...||..||:          |:......|.:.
Mosquito   569 CSQYGTAYTFFTPNNGRQARELLSVLEEAGQQPTVELVEMAKQAPGGKGGRLRYSTQTGYRGSSG 633

  Fly   677 ------------GGGFGG---RGGRFGGGRGGGRRN 697
                        ||||||   .||...||..||.:|
Mosquito   634 MGSYQRRPPFNGGGGFGGPPKYGGGMQGGMMGGMQN 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH_1	92..152	CDD:459630	5/59 (8%)
		DEAD-like_helicase_N	174..663	CDD:475120	215/511 (42%)
LOC1280623	XP_320481.4	DEAD-like_helicase_N	115..633	CDD:475120	220/544 (40%)