Protein Alignment CG7878 and LOC1278134

DIOPT Version :10

• Sequence 1: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: XP_061516579.1
• Gene: LOC1278134 / 1278134
• VectorBaseID: AGAMI1_009058
• Length: 825
• Species: Anopheles gambiae
• Alignment Length: 810
• Identity: 243/810 - (30%)
• Similarity: 352/810 - (43%)
• Gaps: 212/810 - (26%)

  Fly     3 DLDWDDPNYVEKPAVHQEYSKPNNKYERSIRRDGNSRAYKGDRNDYGGEGRGYRAKRN-----DY 62
            |.|||                .....||...|:...|...|||:         ||:|:     |.
Mosquito    54 DRDWD----------------RRRDRERERHRELQQRDRPGDRD---------RAERDRERDRDR 93

  Fly    63 GGGRRDNRDNYGAGHRDSRDSAGGGGGD------------------------------------- 90
            ...|.:::|.......|.........||
Mosquito    94 DRDRAEDKDKARKDKLDDEQEEELKKGDPKAALTKEDLVKKEPLSLEELLAKKKAEEAARSKPVF 158

  Fly    91 ------FSESLSIASEMVGKVIGRGGSNISRIQNDFNVRVKL--DKCDLIVKITGSIQSNVIDAI 147
                  .:|:|....|.|..:.....:|:.:. .|..|...|  :|.|.:.|         .|..
Mosquito   159 ITKEQRAAEALKRRQEEVAAMKAAAAANVPKF-GDVPVTTLLNREKRDPLDK---------YDRR 213

  Fly   148 NHVRKQVTNSGDRGQDRDNRDHGS-------------------NERYDG---------------- 177
            ...||.:.:..|:.:|.|.|..|:                   .|||.|
Mosquito   214 ERERKAINDERDKDKDTDKRRSGAAGTEPEPVVKDKEKEQEAIRERYLGIVKKKRRVRRLNDRKF 278

  Fly   178 -GGYDRYKGNSYEFNPTSSE-----------------------SNKDNGDLTGIIDWEA------ 212
             ..:|..:..|.::|....|                       .:|..|||......||
Mosquito   279 VFDWDAGEDTSIDYNNLYKERHHVQFYGRGHVAGIDIKEQKRKQSKFYGDLLEKRRTEAEKEQEK 343

  Fly   213 --LNKASIAATAARWSKCPPLTKNFYKEAPEVANLTKSEIERIREENNKITVSYVFEPKEGETSP 275
              |.|........:|.       :.:....||..:|:.:....||:.| ||:      |.|:
Mosquito   344 VRLKKVKKKEDKQKWD-------DRHWSEKEVDEMTERDWRIFREDYN-ITI------KGGK--- 391

  Fly   276 PIPNPV--WTFEQCFAEYPDMLEEITKMGFSKPSPIQSQAWPILLQGHDMIGIAQTGTGKTLAFL 338
             ||||:  | .|..|.:  ::||.|.|:|:..|:|||.||.||.||..|:||||:||:|||||||
Mosquito   392 -IPNPIRSW-LESGFPK--EILEIIDKVGYKDPTPIQRQAIPIGLQNRDIIGIAETGSGKTLAFL 452

  Fly   339 LPGMIHTEYQSTPRGTR-----GGANVLVLAPTRELALQIEMEVKKYSF-RGMKAVCVYGGGNRN 397
            :|  :.|..||.|:..|     .|...::||||||||.|||.|.:|:.. .|::.|.|.||.:|.
Mosquito   453 IP--LLTWIQSLPKIDRLETADQGPYAIILAPTRELAQQIEEETQKFGTPLGIRTVVVVGGLSRE 515

  Fly   398 MQISDLERGAEIIICTPGRLNDLIMANVIDVSTITYLVLDEADRMLDMGFEPQIRKVM-----LD 457
            .|...|..|.||:|.|||||.|::....:.::..||:|:||||||:||||||.::|::     .:
Mosquito   516 EQGFRLRLGCEIVIATPGRLIDVLENRYLVLNQCTYIVMDEADRMIDMGFEPDVQKILEYMPVSN 580

  Fly   458 IRPD--------------------RQTIMTSATWPPGVRRLAQSYMKNPIQVCVGSLDLAATHSV 502
            ::||                    |||:|.:||.||.|.|||::|::.|..|.:||:. ..|...
Mosquito   581 LKPDTEEAEDASKLMENFNTKKKYRQTVMFTATMPPAVERLARTYLRRPATVYIGSIG-KPTERT 644

  Fly   503 KQIIKLMEDDMDKFNTITSFVKNMSSTDKIIIFCGRKVRADDLSSELTLDGFMTQCIHGNRDQMD 567
            :|||.:|.:: ||...:.. :.:.......|||..:|..||.|:..|...|:....:||.:.|..
Mosquito   645 EQIIHIMGEN-DKRKKLME-ILSRGVEPPCIIFVNQKKGADVLAKGLEKLGYNACTLHGGKGQEQ 707

  Fly   568 REQAIADIKSGVVRILVATDVASRGLDIEDITHVINYDFPHNIEEYVHRVGRTGRAGRQGTSISF 632
            ||.|:|.:|:|...||||||||.||:||:|::.|||||...:||:|.||:|||||||:.|.:|||
Mosquito   708 REYALASLKNGSKDILVATDVAGRGIDIKDVSLVINYDMAKSIEDYTHRIGRTGRAGKTGCAISF 772

  Fly   633 FTREDWAMAKELIEILQEAEQEV-PDELHN 661
            .|::|..:..:|.::|..:...| |.||.|
Mosquito   773 CTKDDSHLFYDLKQMLMSSPVSVCPPELMN 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7878	NP_649767.1	KH_1	92..152	CDD:459630	12/61 (20%)
		DEAD-like_helicase_N	174..663	CDD:475120	203/570 (36%)
LOC1278134	XP_061516579.1	None